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Torsten Richard Wiemann

from Encinitas, CA
Age ~64

Torsten Wiemann Phones & Addresses

  • 1964 Circle Park Ln, Encinitas, CA 92024 (760) 632-9460 (760) 753-4920
  • 158 Florita St, Encinitas, CA 92024 (760) 753-4920
  • 1355 Rubenstein Ave, Cardiff by the Sea, CA 92007 (760) 753-4920
  • 1905 Alga Rd, Carlsbad, CA 92009 (760) 929-0217
  • 1905 Alga Rd #A, Carlsbad, CA 92009 (760) 929-0217
  • 7560 Charmant Dr #1537, San Diego, CA 92122 (858) 929-0217

Work

Company: National university san diego - San Diego, CA

Education

School / High School: Medicinal Chemistry Institute Jan 2001

Skills

Medicinal Chemistry

Industries

Pharmaceuticals

Resumes

Resumes

Torsten Wiemann Photo 1

Principal Scientist

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Location:
1964 Circle Park Ln, Encinitas, CA 92024
Industry:
Pharmaceuticals
Work:
Aspyrian Therapeutics, Inc
Principal Scientist

Aspyrian Therapeutics, Inc
Principal Scientist, Chemistry

Platt College 2010 - 2012
Instructor

Califia Bio Inc. Feb 2009 - Jul 2010
Group Leader

Galapagos Feb 2007 - Feb 2009
Principal Scientist
Education:
University of Hamburg 1989 - 1993
Doctorates, Doctor of Philosophy, Organic Chemistry
Skills:
Medicinal Chemistry
Torsten Wiemann Photo 2

Torsten Wiemann Encinitas, CA

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Work:
National University San Diego
San Diego, CA
Sep 2010 to Jun 2012

Califia Bio

Feb 2009 to Jul 2010
Group Leader

Biofocus DPI

Feb 2007 to Feb 2009
Principal Scientist

Vertex Pharmaceuticals

May 2005 to Oct 2006
Temporary Scientist

Senomyx, Inc

Nov 2003 to Aug 2004
Principal Scientist

Incyte San Diego
San Diego, CA
May 1999 to Nov 2003
Senior Chemist

Cypros Pharmaceutical Corporation

Sep 1995 to May 1999
Medicinal Chemist

Scripps Research Institute

Jun 1993 to Aug 1995
Postdoctoral fellow

University of Orlans

Nov 1992 to Dec 1992
Professor Patrick Rollin

University of Hamburg, Germany
Hamburg
Oct 1989 to Oct 1992
Teaching Assistant and Research Assistant

Rehovot, Israel

Aug 1989 to Sep 1989
Research in the laboratory of Professor Uri Zehavi

Publications

Us Patents

N-Substituted Heterocycles For The Treatment Of Hypercholesteremia, Dyslipidemia And Other Metabolic Disorders; Cancer, And Other Diseases

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US Patent:
7071218, Jul 4, 2006
Filed:
Nov 15, 2002
Appl. No.:
10/298024
Inventors:
Magnus Pfahl - Solana Beach CA, US
Catherine Tachdjian - San Diego CA, US
Lyle W. Spruce - Chula Vista CA, US
Hussien A. Al-Shamma - Encinitas CA, US
Mohamed Boudjelal - San Diego CA, US
Andrea N. Fanjul - San Diego CA, US
Torsten R. Wiemann - Encinitas CA, US
David P. M. Pleynet - San Diego CA, US
Assignee:
Incyte San Diego Incorporated - San Diego CA
Ortho McNeil Pharmaceutical Inc. - Rariton NJ
International Classification:
A61K 31/426
C07D 277/36
C07D 401/02
US Classification:
514342, 514369, 548183, 548226, 5483171
Abstract:
The present invention relates to certain compounds of Formula (I) which can be useful in the treatment of diseases, such as, cancer, metabolic disorders, Type 2 Diabetes, dyslipidemia and/or hyperchloesterolemia:.

Heterocyclic Derivatives For The Treatment Of Cancer And Other Proliferative Diseases

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US Patent:
7153875, Dec 26, 2006
Filed:
Mar 7, 2002
Appl. No.:
10/094142
Inventors:
Magnus Pfahl - Solana Beach CA, US
Catherine Tachdjian - San Diego CA, US
Hussien A. Al-Shamma - Encinitas CA, US
Andrea Fanjul - San Diego CA, US
David P.M. Pleynet - San Diego CA, US
Lyle W. Spruce - Chula Vista CA, US
Torsten R. Wiemann - Cardiff by the Sea CA, US
Jason B. Ibarra - Imperial Beach CA, US
Assignee:
Incyte San Diego - Wilmington DE
International Classification:
C07D 401/06
A61K 31/44
US Classification:
514342, 5462697
Abstract:
The invention relates to certain heterocyclic compounds useful for the treatment of cancer and other diseases, having the Formula (I):.

2-Substituted Thiazolidinone And Oxazolidinone Derivatives For The Inhibition Of Phosphatases And The Treatment Of Cancer

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US Patent:
20040097566, May 20, 2004
Filed:
Dec 6, 2002
Appl. No.:
10/313341
Inventors:
Magnus Pfahl - Solana Beach CA, US
Hussien Al-Shamma - Encinitas CA, US
Andrea Giachino - San Diego CA, US
David Pleynet - San Diego CA, US
Haifeng Bao - San Diego CA, US
Lyle Spruce - Chula Vista CA, US
Christopher Cow - San Diego CA, US
Catherine Tachdjian - San Diego CA, US
James Zapf - San Diego CA, US
Torsten Wiemann - Encinitas CA, US
International Classification:
A61K031/426
A61K031/421
C07D277/32
C07D263/18
C07D413/02
C07D417/02
US Classification:
514/369000, 514/376000, 548/182000, 548/225000
Abstract:
The present invention relates to certain substituted heterocycles, including 2-substituted thiazolidinone and 2-substituted oxazolidinone compounds. These compounds are useful in the treatment of diseases related to uncontrolled cellular proliferation, such as cancer or precancerous conditions. The compounds are also useful for modulating lipid and/or carbohydrate metabolism, and treating Type II diabetes, hyperglycemia or obesity, and for treating inflammatory diseases such as arthritis. Some disclosed embodiments of the invention relate to compounds having the structures indicated below, or a pharmaceutically acceptable salt thereof.

Benzoxazole, Benzothiazole, And Benzimidazole Derivatives For The Treatment Of Cancer And Other Diseases

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US Patent:
20050014767, Jan 20, 2005
Filed:
Jan 29, 2004
Appl. No.:
10/769725
Inventors:
Magnus Pfahl - Solana Beach CA, US
Catherine Tachdjian - San Diego CA, US
Torsten Wiemann - Encinitas CA, US
Christopher Cow - San Diego CA, US
Lyle Spruce - Chula Vista CA, US
Andrea Giachino - San Diego CA, US
Allan Kaspar - San Diego CA, US
James Zapf - San Diego CA, US
International Classification:
A61K031/497
A61K031/4439
A61K031/423
A61K031/4184
US Classification:
514255050, 514337000, 514338000, 514375000, 514394000, 544405000, 546272700, 548215000, 548304700
Abstract:
The invention relates to certain compounds whose structures are shown below, and their pharmaceutically acceptable salts and prodrugs, and pharmaceutical compositions thereof, which are useful for treating treating diseases of uncontrolled cellular proliferation, including cancer. wherein:

N-Substituted Heterocycles For The Treatment Of Hypercholesteremia, Dyslipidemia And Other Metabolic Disorders; Cancer, And Other Diseases

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US Patent:
20060160796, Jul 20, 2006
Filed:
Mar 20, 2006
Appl. No.:
11/385204
Inventors:
Magnus Pfahl - Solana Beach CA, US
Catherine Tachdjian - San Diego CA, US
Lyle Spruce - Chula Vista CA, US
Hussien Al-Shamma - Encinitas CA, US
Mohamed Boudjelal - San Diego CA, US
Andrea Fanjul - San Diego CA, US
Torsten Wiemann - Encinitas CA, US
David Pleynet - San Diego CA, US
International Classification:
A61K 31/538
A61K 31/517
A61K 31/498
A61K 31/4709
A61K 31/427
A61K 31/423
A61K 31/422
C07D 413/02
C07D 417/02
US Classification:
514230500, 514266200, 514249000, 514369000, 514375000, 514376000, 544284000, 544354000, 544092000, 548181000, 548217000, 548227000, 514312000, 546158000
Abstract:
The present invention relates to certain compounds of Formula (I) which can be useful in the treatment of diseases, such as, cancer, metabolic disorders, Type 2 Diabetes, dyslipidemia and/or hyperchloesterolemia:

Mlk Inhibitors And Methods Of Use

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US Patent:
20120053175, Mar 1, 2012
Filed:
Nov 25, 2009
Appl. No.:
13/131193
Inventors:
Harris A. Gelbard - Pittsford NY, US
Stephen Dewhurst - Rochester NY, US
Val S. Goodfellow - Encinitas CA, US
Colin J. Loweth - San Marcos CA, US
Torsten Wiemann - Encinitas CA, US
Assignee:
UNIVERSITY OF ROCHESTER - Rochester NY
International Classification:
A61K 31/5377
C07D 487/04
A61K 31/437
A61K 31/496
A61P 25/24
A61K 31/4985
A61P 25/28
A61P 25/16
A61P 25/00
A61P 27/16
C07D 471/04
A61K 31/506
US Classification:
5142342, 546113, 544362, 544331, 544296, 544350, 544117, 544118, 514300, 51425304, 514275, 514249
Abstract:
Provided are compounds having an inhibitory effect on Mixed Lineage Kinases. Also provided are pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by Mixed Lineage Kinase inhibition. Also provided are methods of treatment of neuropsychiatric disorders which comprise the inhibition of Mixed Lineage Kinases.

Bicyclic Heteroaryl Kinase Inhibitors And Methods Of Use

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US Patent:
20130203755, Aug 8, 2013
Filed:
May 24, 2011
Appl. No.:
13/698829
Inventors:
Harris A. Gelbard - Pittsford NY, US
Stephen Dewhurst - Rochester NY, US
Val S. Goodfellow - Encinitas CA, US
Torsten Wiemann - Encinitas CA, US
Satheesh Babu Ravula - San Diego CA, US
Colin J. Loweth - San Marcos CA, US
Assignee:
UNIVERSITY OF ROCHESTER - Rochester NY
International Classification:
A61K 31/437
A61K 31/444
A61K 31/496
A61K 45/06
C07D 487/04
A61K 31/4985
A61K 31/5377
C07D 471/04
A61K 31/506
US Classification:
5142342, 546113, 514300, 544362, 51425304, 544331, 514275, 544296, 544350, 514249, 544117, 544118, 435184
Abstract:
Provided are compounds having an inhibitory effect on kinases including Mixed Lineage Kinases. Also provided are pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions that are affected by Mixed Lineage Kinase inhibition. Also provided are methods of treatment of neuropsychiatric disorders that comprise the inhibition of Mixed Lineage Kinases.

Neuroprotective Poly-Guanidino Compounds Which Block Presynaptic N And P/Q Calcium Channels

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US Patent:
60638192, May 16, 2000
Filed:
Feb 18, 1998
Appl. No.:
9/026415
Inventors:
Paul J. Marangos - La Costa CA
Brian W. Sullivan - Escondido CA
Torsten Wiemann - La Costa CA
Anne M. Danks - Solana Beach CA
Marina Sragovicz - San Diego CA
Lewis R. Makings - Encinitas CA
Assignee:
Cypros Pharmaceutical Corp. - Carlsbad CA
International Classification:
A61K 3155
C07C23305
US Classification:
514634
Abstract:
Neuroprotective drugs are disclosed with at least 3 branches extending outwardly from a center atom or group, each branch having a guanidino group at its terminus. All branches preferably should be identical, and distributed around the center atom or group in a radial manner. Three branches can be bonded to a nitrogen atom, or four branches can be coupled to a carbon atom; other center groups include stable aromatic, cycloalkyl, heterocyclic, or bicyclic structures. Starting reagents are disclosed with a center atom or group, and with reactive groups (such as primary amines or hydroxyl groups) at the ends of short "spacer chains" bonded to the center atom or group. Reagents derived from arginine (an amino acid having a terminal guanidino group) can be bonded to these center components, using protective groups on the arginyl reagents to ensure desired final products with accessible guanidino groups at the ends of spacer chains. Alternately, guanylating agents can be used to directly convert primary amine groups at the ends of spacer chains, on starting reagents, into guanidino groups. These drugs can be injected intravenously into patients suffering from ischemic or hypoxic crises (stroke, cardiac arrest, loss of blood, suffocation, etc.
Torsten Richard Wiemann from Encinitas, CA, age ~64 Get Report