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Thomas F Serwold

from Cambridge, MA
Age ~55

Thomas Serwold Phones & Addresses

  • 30 Banks St, Cambridge, MA 02138
  • Brookline, MA
  • Redwood City, CA
  • 1831 Arlington Blvd, El Cerrito, CA 94530
  • Berkeley, CA
  • Edmonds, WA

Work

Position: Personal Care and Service Occupations

Education

Degree: High school graduate or higher

Publications

Us Patents

Eraap Modulators Regulate Immune Responses

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US Patent:
7232570, Jun 19, 2007
Filed:
Dec 13, 2005
Appl. No.:
11/300169
Inventors:
Nilabh Shastri - Richmond CA, US
Thomas Serwold - El Cerrito CA, US
Assignee:
Regents of the University of California - Oakland CA
International Classification:
A61K 38/08
A61K 38/04
US Classification:
4241851, 530330
Abstract:
An immune response is modulated by selectively inhibiting ERAAP (an acronym for ER aminopeptidase associated with antigen processing) and confirming a resultant immune response modulation. More particularly, the method comprises contacting a patient determined to be in need of immune response modulation with a physiologically acceptable dosage composition comprising an effective amount of an inhibitor of ERAAP activity; confirming a resultant inhibition of said ERAAP activity and confirming a resultant immune response modulation in the patient. A variety of selective inhibitors are shown to be effective, including amino thiols, such as leucine thiol, ERAAP-specific antibody complementarity-determining region, and an ERAAP-specific siRNA.

Eraap Modulators Regulate Immune Responses

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US Patent:
20030228314, Dec 11, 2003
Filed:
Jun 6, 2002
Appl. No.:
10/164012
Inventors:
Nilabh Shastri - Richmond CA, US
Thomas Serwold - El Cerrito CA, US
Assignee:
The Regents of the University of California
International Classification:
A61K039/395
A61K048/00
US Classification:
424/146100, 514/044000
Abstract:
An immune response is modulated by selectively inhibiting ERAAP (an acronym for ER aminopeptidase associated with antigen processing) and confirming a resultant immune response modulation. More particularly, the method comprises contacting a patient determined to be in need of immune response modulation with a physiologically acceptable dosage composition comprising an effective amount of an inhibitor of ERAAP activity; confirming a resultant inhibition of said ERAAP activity and confirming a resultant immune response modulation in the patient. A variety of selective inhibitors are shown to be effective, including amino thiols, such as leucine thiol, ERAAP-specific antibody complementarity-determining region, and an ERAAP-specific siRNA.
Thomas F Serwold from Cambridge, MA, age ~55 Get Report