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Thomas Paul Jarvie

from Branford, CT
Age ~61
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Also known as:
Thomas P Jarvie, Thomas Dr Jarvie, Thomas A Jarvie, Tom P Jarvie, Thos P Jarvie
Phone and address:
13 Old Smugglers Rd, Branford, CT 06405
(203) 448-7946
Related to:
Sherry A Reese, 74
Connected to:
Allison R Jarvie, 47Andrea L Jarvie, 36Elizabeth J Jarvie, 53Greg A Jarvie, 64Kevin Jarvie, 67Lisa N Jarvie, 55Matthew D Jarvie, 43William R Jarvie, 39James H Jarvies, 72John C Jarvies, 47

Thomas Jarvie Phones & Addresses

  • 13 Old Smugglers Rd, Branford, CT 06405 (203) 448-7946 (203) 488-7946
  • Montrose, PA
  • Middletown, CT
  • Springfield, VA
  • Seattle, WA
  • State College, PA
  • 13 Old Smugglers Rd, Branford, CT 06405

Resumes

Resumes

Thomas Jarvie Photo 1

Chief Executive Officer And Co-Founder

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Location:
13 Old Smugglers Rd, Branford, CT 06405
Industry:
Biotechnology
Work:
Shoreline Biome
Chief Executive Officer and Co-Founder
454 Life Sciences 2012 - 2015
Technical Product Manager
454 Life Sciences 2009 - 2012
International Product Manager
454 Life Sciences 2005 - 2009
Technical Application Manager
454 Life Sciences 2003 - 2005
Group Leader, Operations
Education:
William & Mary
Bachelors, Bachelor of Science, Chemistry University of California, Berkeley
Doctorates, Doctor of Philosophy, Philosophy, Chemistry
Skills:
Genomics
Molecular Biology
Dna Sequencing
Sequencing
Biotechnology
Laboratory Automation
Life Sciences
Drug Discovery
Pcr
Bioinformatics
Assay Development
Genetics
Dna
Lifesciences
Commercialization
Chemistry
Medical Devices
Protein Chemistry
Microbiology
Cancer
R&D
Technology Transfer
Research and Development
Validation
Pharmaceutical Industry
Hardware Diagnostics
Sequence Analysis
Science
Hplc
Biomarker Discovery
Medical Diagnostics
Dna Extraction
Glp
Polymerase Chain Reaction
Good Laboratory Practice
Thomas Jarvie Photo 2

Thomas Jarvie

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Business Records

Name / Title
Company / Classification
Phones & Addresses
Thomas Jarvie
Co-Founder
SHORELINE BIOME, LLC
Business Services at Non-Commercial Site
56 Country Way, Wallingford, CT 06492
13 Old Smugglers Rd, Branford, CT 06405
Thomas S Jarvie
THE BAYPORT GROUP, LTD
Thomas Jarvie
TSJ MANAGEMENT LLC
Thomas Jarvie
SOUTHLAND POINTE, LLC
Thomas Jarvie
DRIFTWOOD MANOR LLC

Publications

Us Patents

Method For Identifying A Biomolecule

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US Patent:
20040029155, Feb 12, 2004
Filed:
Apr 29, 2003
Appl. No.:
10/426179
Inventors:
Jonathan Rothberg - Guilford CT, US
Michael McKenna - New Haven CT, US
Paul Predki - Branford CT, US
Andreas Windemuth - Woodbridge CT, US
Richard Shimkets - West Haven CT, US
Maithreyan Srinivasan - Hamden CT, US
Thomas Jarvie - Branford CT, US
Pascale Pochart - New Haven CT, US
Assignee:
CuraGen Corporation
International Classification:
C12Q001/68
C12P019/34
US Classification:
435/006000, 435/091200
Abstract:
Disclosed are methods for identifying nucleic acids in a sample of nucleic acids in which nucleic acids are initially unequal amounts. The methods include partitioning the starting population of nucleic acids to form one or more subpopulations, and then identifying nucleic acids that are present in different amounts in the partitioned nucleic acid sample as compared to the starting population. Also disclosed are methods of generating databases based on sizes of DNA fragments and size-based sequencing of those fragments.

Screening Method For Ligand-Protein Interactions

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US Patent:
20050037375, Feb 17, 2005
Filed:
Dec 29, 2003
Appl. No.:
10/748805
Inventors:
Vimal Mehta - Guilford CT, US
Thomas Jarvie - Branford CT, US
Jonathan Rothberg - Guilford CT, US
International Classification:
C12Q001/68
G01N033/53
G01N033/567
US Classification:
435006000, 435007200
Abstract:
A rapid method and kit is provided for identifying the targets of biologically active small molecules to identify new drugs that are capable of specific therapeutic effects as well as to identify novel small molecules including agonists and antagonists that may bind selected targets.

Method For Distance Measurements With Solid-State Nmr

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US Patent:
60279419, Feb 22, 2000
Filed:
May 15, 1996
Appl. No.:
8/648609
Inventors:
Thomas P. Jarvie - Middletown CT
Joel S. Bader - Branford CT
Gregory T. Went - Madison CT
Assignee:
CuraGen Corporation - New Haven CT
International Classification:
G01N 2400
G01V 300
US Classification:
436173
Abstract:
This invention includes methods for analyzing data generated by various solid-state NMR experiments, including rotational echo double resonance (REDOR), transferred echo double resonance (TEDOR), dipolar recoupling at the magic angle (DRAMA), dipolar recoupling with a windowless sequence (DRAWS), and melding of spin-locking and DRAMA (MELODRAMA). The methods are based alternately on a new analytical transform or the maximum entropy method and their multi-dimensional extensions. They permit simultaneous, multiple distance measurements of high accuracy and precision, even from nuclei with identical chemical shifts. By providing high quality easily obtained distance measurement from disordered solid state materials, this invention also improves drug discovery and design through fast determination of structures of pharmaceutical lead compounds, drug molecules, or their targets.

High Throughput Method For Identification And Sequencing Of Unknown Microbial And Eukaryotic Genomes From Complex Mixtures

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US Patent:
20210130914, May 6, 2021
Filed:
Jan 11, 2021
Appl. No.:
17/146427
Inventors:
- Farmington CT, US
Thomas Jarvie - Branford CT, US
Assignee:
Shoreline Biome, LLC - Farmington CT
International Classification:
C12Q 1/6888
C12Q 1/689
C12Q 1/6816
Abstract:
Disclosed are methods for screening biological samples for the presence unknown microbes, such as bacteria and archaea or unknown eukaryotes using rRNA gene sequences or other highly conserved genetic regions, across multiple biological samples using a unique sequence tag (barcode) corresponding to the sample. The screening process tracks the unknown microbe or eukaryote in a diluted sample where the DNA has been prepared using whole genome amplification. The whole genome of the unknown microbe or eukaryote is then sequenced and assembled.

Combined Lysis Protocol For Comprehensive Cell Lysis

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US Patent:
20210032618, Feb 4, 2021
Filed:
Aug 19, 2020
Appl. No.:
16/996996
Inventors:
- Farmington CT, US
Thomas Jarvie - Branford CT, US
Assignee:
Shoreline Biome, LLC - Farmington CT
International Classification:
C12N 15/10
C12Q 1/6874
G01N 33/569
C12N 1/06
C12Q 1/6806
Abstract:
Disclosed are methods for lysis of cells, such as bacteria present in microbiomes, that combine three lysis steps—(1) heat, (2) detergent and (3) base—into a single step and that can be completed in a short period of time, e.g., a few minutes. The methods combine a normally incompatible detergent and base lysis, allows for simplified removal of detergent after lysis, and importantly, yields improved quantities of genomic DNA (gDNA) from difficult to lyse bacteria.

Multiple Specific/Nonspecific Primers For Pcr Of A Complex Gene Pool

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US Patent:
20190352712, Nov 21, 2019
Filed:
May 1, 2019
Appl. No.:
16/400250
Inventors:
- Farmington CT, US
Thomas Jarvie - Branford CT, US
Ryan Beach - Simsbury CT, US
Christina Clark - Farmington CT, US
Dawn Gratalo - Farmington CT, US
Assignee:
Shoreline Biome, LLC - Farmington CT
International Classification:
C12Q 1/6876
Abstract:
Disclosed are compositions and methods for single-step PCR of a sample containing a complex target gene pool that can simultaneously amplify a wide variety of variant target gene sequences common to the sample while maintaining the original ratios of gene variants. The compositions and methods described herein utilize (1) a gene-specific primer pool that contains multiple variants that occur in a sample containing a complex mixture of target sequences that are both required for amplification of variants in the mixture which may introduce amplification bias, with () a non-specific PCR primer that is designed to target multiple gene-specific primer variants and eliminate amplification bias.

Semi-Dry Bead Beating Method For Microbial Lysis And Device For Performing Same

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US Patent:
20190024076, Jan 24, 2019
Filed:
Jul 16, 2018
Appl. No.:
16/036006
Inventors:
- Farmington CT, US
Thomas Jarvie - Branford CT, US
Ryan Beach - Simsbury CT, US
Jeff Whynall - Killingworth CT, US
International Classification:
C12N 15/10
C12N 1/06
C12M 1/02
Abstract:
Disclosed are methods and devices for lysing cells to release extract genomic DNA (gDNA). The methods use a mixture of microscopic glass beads and cells (for example, spores) that form a semi-dry cake that clings to a larger metal ball and the sides of the tube during bead beating lysis, greatly improving the efficiency of the bead beating process. The devices produce a chaotic motion which ensures that sufficient force is generated to open the cells, and that the metal ball impacts are distributed across the interior surface of the container so that all of the cell mixture is subjected to sufficient impacts to break the cells. As a result, spores and other difficult-to-lyse microbes, can be opened in seconds. The method reduces the number of steps and hands-on time by rapidly opening difficult to lyse cells, while preserving the integrity of the DNA.

Combined Lysis Protocol For Comprehensive Cell Lysis

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US Patent:
20180187181, Jul 5, 2018
Filed:
Dec 26, 2017
Appl. No.:
15/854157
Inventors:
- Farmington CT, US
Thomas Jarvie - Branford CT, US
Assignee:
Shoreline Biome, LLC - Farmington CT
International Classification:
C12N 15/10
C12Q 1/6874
C12Q 1/6806
C12N 1/06
G01N 33/569
Abstract:
Disclosed are methods for lysis of cells, such as bacteria present in microbiomes, that combine three lysis steps—(1) heat, (2) detergent and (3) base—into a single step and that can be completed in a short period of time, e.g., a few minutes. The methods combine a normally incompatible detergent and base lysis, allows for simplified removal of detergent after lysis, and importantly, yields improved quantities of genomic DNA (gDNA) from difficult to lyse bacteria.
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Thomas Paul Jarvie from Branford, CT, age ~61 Get Report