Resumes
Resumes
Te King Phones & Addresses
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Little Ferry, NJ
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Flushing, NY
Work
Company:
The rockefeller university
Address:
1230 York Ave, New York, NY 10065
Phones:
(212) 327-7511
Position:
Professional em
Industries:
Noncommercial Research Organizations
Business Records
Name / Title
Company / Classification
Phones & Addresses
Professional Em
The Rockefeller University
Noncommercial Research Organizations
Noncommercial Research Organizations
1230 York Ave, New York, NY 10065
Professional Emeritus
The Rockefeller University
Noncommercial Research Organizations
Noncommercial Research Organizations
1230 York Ave, New York, NY 10065
Professional Em, Professional Emeritus
Rockefeller University
Research · Noncommercial Medical Research Hospital · Noncommercial Research Organization College/University · Noncommercial Research Organization · College/University · Colleges, Universities, and Pr
Research · Noncommercial Medical Research Hospital · Noncommercial Research Organization College/University · Noncommercial Research Organization · College/University · Colleges, Universities, and Pr
1230 York Ave, New York, NY 10065
123 York Ave, New York, NY 10021
(212) 327-7511, (212) 327-8078, (212) 327-8666, (212) 327-8000
123 York Ave, New York, NY 10021
(212) 327-7511, (212) 327-8078, (212) 327-8666, (212) 327-8000
Professional Em
The Rockefeller University
Noncommercial Research Organizations
Noncommercial Research Organizations
1230 York Ave, New York, NY 10065
Professional Emeritus
The Rockefeller University
Noncommercial Research Organizations
Noncommercial Research Organizations
1230 York Ave, New York, NY 10065
Publications
Us Patents
Cloning And Recombinant Production Of Vespid Venom Enzymes, Such As Phospholipase And Hyaluronidase, And Immunological Therapies Based Thereon
View pageUS Patent:
6372471, Apr 16, 2002
Filed:
Oct 1, 1998
Appl. No.:
09/166205
Inventors:
Te Piao King - New York NY
Assignee:
The Rockefeller University - New York NY
International Classification:
C12N 920
US Classification:
435198, 4352523, 4353201, 536 232, 530350, 424 941
Abstract:
The present invention is directed to nucleic acids encoding vespid venom enzymes, or fragments thereof, recombinant vectors comprising such nucleic acids, and host cells containing the recombinant vectors. The invention is further directed to expression of such nucleic acids to produce recombinant vespid venom enzymes, or recombinant fragments, derivatives or analogs thereof. Such recombinant products are useful for diagnosis of allergy and for therapeutic treatment of allergy. In specific embodiments, the present invention provides nucleic acids encoding, and complete nucleotide and amino acids sequences for, vespid venom phospholipase, for example, phospholipase A , and vespid venom hyaluronidase, for example, hyaluronidase. Moreover, agents and pharmaceutical compositions are disclosed which modulate the immune systems ability to attack an immunogen, along with methods of using such agents and pharmaceutical compositions to modulate immune response, or to treat immune system related diseases or disorders, or symptoms related thereto.
Cloning And Recombinant Production Of Polistinae Venom Enzymes, Such As Phospholipase And Hyaluronidase, And Immunological Therapies Based Thereon
View pageUS Patent:
6652851, Nov 25, 2003
Filed:
May 24, 2001
Appl. No.:
09/806658
Inventors:
Te Piao King - New York NY
Assignee:
The Rockefeller University - New York NY
International Classification:
A61K 3846
US Classification:
424 9462, 435 691, 435201, 4352523, 43525233, 435325, 43525411, 4353201, 536 232, 536 235, 536 231, 530350
Abstract:
A unique clone of a Polistinae venom enzyme, recombinantly produced Polistinae venom enzymes, and methods of using the recombinant enzymes are provided. In a specific example, both phospholipase and hyaluronidase cDNA from contain apparent âintronicâ sequences. In still a further embodiment, genetic engineering permits the construction of the âintronicâ sequences to yield a useful coding sequence for expression of mature Polistinae venom enzyme proteins.
Cloning And Recombinant Production Of Polistinae Venom Enzymes, Such As Phospholipase And Hyaluronidase, And Immunological Therapies Based Thereon
View pageUS Patent:
7060265, Jun 13, 2006
Filed:
Oct 17, 2003
Appl. No.:
10/688011
Inventors:
Te Piao King - New York NY, US
Assignee:
The Rockefeller University - New York NY
International Classification:
A61K 38/46
C12N 9/16
C12N 9/16
US Classification:
424 946, 435196, 435198, 536 232
Abstract:
A unique clone of a Polistinae venom enzyme, recombinantly produced Polistinae venom enzymes, and methods of using the recombinant enzymes are provided. In a specific example, both phospholipase and hyaluronidase cDNA from contain apparent “intronic” sequences. In still a further enbodiment, genetic engineering permits the construction of the “intronic” sequences to yield a useful coding sequence for expression of mature Polistinae venom enzyme proteins.
Recombinant Hybrid Allergen Constructs With Reduced Allergenicity That Retain Immunogenicity Of The Natural Allergen
View pageUS Patent:
20030039660, Feb 27, 2003
Filed:
Mar 4, 2002
Appl. No.:
10/091135
Inventors:
Te King - New York NY, US
Michael Spangfort - Viken, SE
Michael Spangfort - Viken, SE
Assignee:
The Rockefeller University
International Classification:
A61K039/00
C12N009/00
C12N009/00
US Classification:
424/185100, 424/275100, 435/183000
Abstract:
Disclosed are recombinant hybrid proteins having at least one antigenic peptide sequence introduced into a scaffold protein that retain a native conformation. Also disclosed are recombinant nucleic acids and vectors encoding the hybrid proteins. The hybrid proteins retain immunogenicity but exhibit reduced allergenicity. The hybrid proteins are therefore particularly useful for therapeutic treatment of allergy.
Immunomodulatory Peptides Of Vespid Antigen 5
View pageUS Patent:
61068446, Aug 22, 2000
Filed:
Aug 6, 1998
Appl. No.:
9/130287
Inventors:
Te Piao King - New York NY
Assignee:
The Rockfeller University - New York NY
International Classification:
A61K 3935
A61K 3900
A61K 3936
A61K 3900
A61K 3936
US Classification:
4242751
Abstract:
The present invention is directed to immunogenic peptides from vespid antigen 5. These immunogenic peptides can be used in immunotherapy for vespid venom allergic individuals. The present invention is thus directed to T cell epitopes of vespid antigen 5 that can anergize T cell responses in sensitive individuals.
Immunomodulatory Peptides Of Vespid Antigen 5
View pageUS Patent:
58042016, Sep 8, 1998
Filed:
Mar 11, 1996
Appl. No.:
8/614935
Inventors:
Te Piao King - New York NY
Assignee:
The Rockefeller University - New York NY
International Classification:
A61K 3935
A61K 3804
A61K 3804
US Classification:
4242751
Abstract:
The present invention is directed to immunogenic peptides from vespid antigen 5. These immunogenic peptides can be used in immunotherapy for vespid venom allergic individuals. The present invention is thus directed to T cell epitopes of vespid antigen 5 that can anergize T cell responses in sensitive individuals.
Cloning And Recombinant Production Of Vespid Venom Phospholipases, And Immunological Therapies Based Thereon
View pageUS Patent:
56122098, Mar 18, 1997
Filed:
Feb 8, 1995
Appl. No.:
8/385745
Inventors:
Te P. King - New York NY
Assignee:
The Rockefeller University - New York NY
International Classification:
C12N 920
C12N 1500
A61K 3800
C07H 2104
C12N 1500
A61K 3800
C07H 2104
US Classification:
435198
Abstract:
The present invention is directed to nucleic acids encoding vespid venom phospholipases, or fragments thereof, recombinant vectors comprising such nucleic acids, and host cells containing the recombinant vectors. The invention is further directed to expression of such nucleic acids to produce recombinant vespid venom phospholipases, or recombinant fragments, derivatives or analogs thereof. Such recombinant products are useful for diagnosis of allergy and for therapeutic treatment of allergy. In specific embodiments, the present invention provides nucleic acids encoding, and complete nucleotide and amino acids sequences for, vespid venom phospholipase A1, for example, Dolichovespula maculata phospholipase A. sub. 1 and Vespula vulgaris phospholipase A1.
Nucleic Acid And Recombinant Production Of Vespid Venom Hyaluronidase
View pageUS Patent:
55938779, Jan 14, 1997
Filed:
Jan 11, 1994
Appl. No.:
8/180209
Inventors:
Te P. King - New York NY
Assignee:
The Rockefeller University - New York NY
International Classification:
C12N 1555
C12N 1570
C12N 1570
US Classification:
435197
Abstract:
The present invention is directed to nucleic acids encoding vespid venom enzymes, or fragments thereof, recombinant vectors comprising such nucleic acids, and host cells containing the recombinant vectors. The invention is further directed to expression of such nucleic acids to produce recombinant vespid venom enzymes, or recombinant fragments, derivatives or analogs thereof. Such recombinant products are useful for diagnosis of allergy and for therapeutic treatment of allergy. In specific embodiments, the present invention provides nucleic acids encoding, and complete nucleotide and amino acids sequences for, vespid venom phospholipase, for example, Dolichovespula maculata phospholipase and Vespula vulgaris phospholipase, and vespid venom hyaluronidase, for example, Dolichovespula maculata hyaluronidase.