US Patent:
20060019914, Jan 26, 2006
Inventors:
Tayebeh Pourmotabbed - Cordova TN, US
Hisashi Hasegawa - Niigata, JP
Chad Batson - Memphis TN, US
International Classification:
A61K 48/00
Abstract:
The presently disclosed subject matter provides DNA molecules designed to down regulate the expression of MMP genes in a cell. Also provided are compositions comprising the DNA molecules. The presently disclosed subject matter further provides methods of using the DNA molecules to inhibit metastasis of a cancer cell. The presently disclosed subject matter also provides methods of using the DNA molecules to modulate tumor growth in a subject.