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Symon G Erskine

from Haverford, PA
Age ~57

Symon Erskine Phones & Addresses

  • 445 Mulberry Ln, Haverford, PA 19041 (610) 254-8907
  • Wayne, PA
  • Devon, PA

Work

Company: Rhc strategic consultants Oct 2008 Position: Director

Education

Degree: Post Doc School / High School: University of Leicester 1997 to 1999 Specialities: DNA Topoisomerases

Industries

Pharmaceuticals

Resumes

Resumes

Symon Erskine Photo 1

Director Science At Rhc Strategic Consultants

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Position:
Director at RHC Strategic Consultants
Location:
Greater Philadelphia Area
Industry:
Pharmaceuticals
Work:
RHC Strategic Consultants since Oct 2008
Director

GlaxoSmithKline Aug 2005 - Oct 2008
Investigator & Program Leader in Oncology

GlaxoSmithKline Aug 2001 - Aug 2005
Senior Scientist in Onology, Anti-infectives and Diseases of developing world

SmithKline Beecham Feb 1999 - Aug 2001
Scientist in New assay technologies group (UK)
Education:
University of Leicester 1997 - 1999
Post Doc, DNA Topoisomerases
University of Bristol 1992 - 1997
PhD, Enzyme kinetics, DNA-Protein interactions
University of Newcastle-upon-Tyne 1991 - 1992
MSc, Biochemistry, Biophysics

Publications

Us Patents

Compounds And Methods For The Treatment Of Neoplastic Disease

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US Patent:
20030203917, Oct 30, 2003
Filed:
May 20, 2003
Appl. No.:
10/441435
Inventors:
Symon Erskine - Collegeville PA, US
Michael Gwynn - Collegeville PA, US
Neil Pearson - Harlow, GB
Edwina Wilding - Collegeville PA, US
Assignee:
SmithKline Beecham Corporation and SmithKline Beecham p.l.c.
International Classification:
A61K031/496
A61K031/655
A61K031/4709
US Classification:
514/253060, 514/151000, 514/314000
Abstract:
A method of modulating the activity of a aberrant cell topoisomerase enzyme involving contacting the enzyme with a compound that inhibits enzyme-mediated cleavage of a polynucleotide substrate with which the enzyme is in complex. Pharmaceutical compositions containing such compounds may be used to treat neoplasias or to inhibit the growth of certain cancer cells. Screening methods can be employed to identify other compounds for these uses.

Compounds And Methods For The Treatment Of Neoplastic Disease

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US Patent:
6803369, Oct 12, 2004
Filed:
Jul 25, 2001
Appl. No.:
09/912483
Inventors:
Symon G. Erskine - Collegeville PA
Michael Gwynn - Collegeville PA
Neil David Pearson - Harlow, GB
Edwina Imogen Wilding - Collegeville PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
SmithKlineBeecham p.l.c. - Brentford
International Classification:
A61K 31497
US Classification:
51425306, 51425307, 51425308, 514311, 514312, 514313, 514314
Abstract:
A method of modulating the activity of a aberrant cell topoisomerase enzyme involving contacting the enzyme with a compound that inhibits enzyme-mediated cleavage of a polynucleotide substrate with which the enzyme is in complex. Pharmaceutical compositions containing such compounds may be used to treat neoplasias or to inhibit the growth of certain cancer cells. Screening methods can be employed to identify other compounds for these uses.
Symon G Erskine from Haverford, PA, age ~57 Get Report