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Steven Lockton

from San Diego, CA
Age ~46
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Related to:
Bonnie E Cohn, 67Carlos E Vazquez, 72Joshua C Backer, 32Richard Leopold, 53Margaret N Mahedy, 89Marie C Lockton, 45Loretta MahedyOlivia S Mahedy, 49Carol A Mahedy, 81Michael J Mahedy, 48William P Mahedy
Connected to:
Bryan J Lockwald, 57Clemente Lockward, 53Mary H Lockwich, 77Abigail L Lockwood, 40Agnieszka Lockwood, 39Alisa I Lockwood, 73Alisia A Lockwood, 61Angelia Lockwood, 36Arnold G Lockwood, 84Avram C Lockwood, 65

Steven Lockton Phones & Addresses

  • 3319 Mount Tami Ln, San Diego, CA 92111 (858) 737-4509
  • 3212 Eichenlaub St, San Diego, CA 92117 (619) 274-0587 (858) 274-0587
  • Albany, CA
  • Irvine, CA
  • 3212 Eichenlaub St, San Diego, CA 92117 (858) 274-0587

Work

Company: Prometheus laboratories, inc Feb 2011 Position: Sr. bioinformatics scientist

Education

School / High School: University of California- Irvine, CA 2008 Specialities: Ph.D. in Biological Sciences

Skills

Statistics: Multivariate regression • survival analysis • hypothesis testing • ROC analysis • modeling • random forest • SVM • logistic regression • clustering • PCA • mixed models • robust statistics Programming: R (10+ ye... • Perl • UNIX shell Science: Functional genomics/... • microarray • RNA-seq • phylogenetics • clinical data analysis • PCR • sequencing • next-gen. sequencing library prep. • cDNA libraries • electrophoresis • TaqMan • population genetics • biomarker discovery • diagnostics Communication: Data visualiz... • scientific writing • presentation • collaboration Bioinformatics: Bioconduct... • BLAST • clustalw • bowtie/tophat/cufflinks • Cytoscape • MySQL & PostegreSQL • Excel • Geneious • MEGA Operating systems: OS X • Linux • Windows

Resumes

Resumes

Steven Lockton Photo 1

Principal Bioinformatician

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Location:
3545 John Hopkins Ct, San Diego, CA 92121
Industry:
Biotechnology
Work:
Regulus Therapeutics Aug 2017 - Apr 2018
Associate Director, Bioinformatics
Progenity, Inc. Aug 2017 - Apr 2018
Principal Bioinformatician
Regulus Therapeutics Feb 2017 - Aug 2017
Principal Scientist, Bioinformatics
Regulus Therapeutics Dec 2014 - Feb 2017
Senior Scientist, Bioinformatics
Biological Dynamics, Inc. Jul 2014 - Dec 2014
Bioinformatics Scientist
Education:
Uc Irvine 2003 - 2008
Doctorates, Doctor of Philosophy Cardiff University / Prifysgol Caerdydd 1996 - 2000
Bachelors, Bachelor of Science, Genetics
Skills:
Bioinformatics
Genetics
Molecular Biology
Biotechnology
Qpcr
R
Sequencing
Pcr
Dna
Life Sciences
Linux
Genomics
Dna Sequencing
Lifesciences
Biomarker Discovery
Statistical Data Analysis
Modeling
Languages:
English
Steven Lockton Photo 2

Senior Bioinformatics Scientist At Prometheus

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Position:
Senior Bioinformatics Scientist at Prometheus
Location:
Greater San Diego Area
Industry:
Biotechnology
Work:
Prometheus - Greater San Diego Area since Aug 2012
Senior Bioinformatics Scientist
Prometheus Labs Feb 2011 - Aug 2012
Bioinformatics Scientist
Sequenom, Inc Jun 2010 - Feb 2011
Scientist
University of California, Berkeley Sep 2008 - May 2010
Postdoctoral Fellow
Torrey Mesa Research Institute of Syngenta Jan 2001 - Jan 2003
Research Associate
Education:
University of California, Irvine 2003 - 2008
Ph.D, Biological Sciences Cardiff University / Prifysgol Caerdydd 1996 - 2000
B.Sc. (Honors), Genetics
Skills:
Statistical data analysis
Modeling
Bioinformatics
Molecular Biology
Linux
DNA
qPCR
Sequencing
Steven Lockton Photo 3

Steven Lockton San Diego, CA

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Work:
Prometheus Laboratories, Inc

Feb 2011 to 2000
Sr. Bioinformatics Scientist
Sequenom, Inc

2010 to 2011
Scientist I
University of California
Berkeley
2008 to 2010
Postdoctoral Fellow
University of California
Irvine
2003 to 2008
Graduate student researcher
Torrey Mesa Research Institute of Syngenta

2001 to 2003
Research Associate
Education:
University of California
Irvine, CA
2008
Ph.D. in Biological Sciences
University of Wales, Cardiff
Cardiff, AL
1996 to 2000
BS in Genetics
Skills:
Statistics: Multivariate regression, survival analysis, hypothesis testing, ROC analysis, modeling, random forest, SVM, logistic regression, clustering, PCA, mixed models, robust statistics Programming: R (10+ years), Perl, UNIX shell Science: Functional genomics/gene expression, microarray, RNA-seq, phylogenetics, clinical data analysis, PCR, sequencing, next-gen. sequencing library prep., cDNA libraries, electrophoresis, TaqMan, population genetics, biomarker discovery, diagnostics Communication: Data visualization, scientific writing, presentation, collaboration Bioinformatics: Bioconductor (incl. limma), BLAST, clustalw, bowtie/tophat/cufflinks, Cytoscape, MySQL & PostegreSQL, Excel, Geneious, MEGA Operating systems: OS X, Linux, Windows

Publications

Us Patents

Methods For Improving Inflammatory Bowel Disease Diagnosis

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US Patent:
20130225439, Aug 29, 2013
Filed:
Mar 15, 2013
Appl. No.:
13/840779
Inventors:
Steven Lockton - San Diego CA, US
Lisa J. Croner - San Diego CA, US
Frederick A. Fletcher - San Diego CA, US
Thomas Stockfisch - Escondido CA, US
Sharat Singh - Rancho Santa Fe CA, US
Assignee:
Nestec S.A. - Vevey
International Classification:
G01N 33/68
C12Q 1/68
US Classification:
506 9
Abstract:
The present invention provides methods and systems to predict and diagnose inflammatory bowel disease (IBD) and subtypes such as ulcerative colitis (UC) and Crohn's disease (CD) by detecting the presence, absence, level, and/or genotype of one or more sero-genetic-inflammation markers. Advantageously, with the present invention, it is possible to provide a diagnosis of IBD versus non-IBD, to rule out IBD that is inconclusive for CD and UC, and to differentiate between CD and UC with increased accuracy.

Methods, Systems, And Compositions For Counting Nucleic Acid Molecules

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US Patent:
20220282315, Sep 8, 2022
Filed:
Oct 13, 2021
Appl. No.:
17/500422
Inventors:
- San Diego CA, US
Jeffrey BUIS - Ann Arbor MI, US
Sharat SINGH - Rancho Santa Fe CA, US
Jeff PERRY - Ann Arbor MI, US
Steven LOCKTON - San Diego CA, US
Chandni JAIN - San Diego CA, US
International Classification:
C12Q 1/6837
C12Q 1/6853
Abstract:
Compositions and methods, systems, and kits for detecting and quantifying variations in numbers of molecules, particularly variations in gene dosage, e.g., due to gene duplication, or to variations from the normal euploid complement of chromosomes, e.g., trisomy of one or more chromosomes that are normally found in diploid pairs, without digital sequencing.

Methods, Systems, And Compositions For Counting Nucleic Acid Molecules

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US Patent:
20210164029, Jun 3, 2021
Filed:
Jan 15, 2021
Appl. No.:
17/150079
Inventors:
- San Diego CA, US
Jeffrey Buis - Ann Arbor MI, US
Sharat Singh - Rancho Santa Fe CA, US
Jeff Perry - Ann Arbor MI, US
Steven Lockton - San Diego CA, US
Chandni Jain - San Diego CA, US
International Classification:
C12Q 1/6837
C12Q 1/6853
Abstract:
Compositions and methods, systems, and kits for detecting and quantifying variations in numbers of molecules, particularly variations in gene dosage, e.g., due to gene duplication, or to variations from the normal euploid complement of chromosomes, e.g., trisomy of one or more chromosomes that are normally found in diploid pairs, without digital sequencing.

Drug Selection For Non-Small Cell Lung Cancer Therapy

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US Patent:
20160032403, Feb 4, 2016
Filed:
Jul 29, 2015
Appl. No.:
14/812979
Inventors:
- Vevey, CH
Phillip Kim - Irvine CA, US
Steven Lockton - San Diego CA, US
Assignee:
NESEC S.A, - Vevey
International Classification:
C12Q 1/68
G01N 33/574
Abstract:
The present invention provides methods for selecting a suitable anticancer drug for the treatment of patient with non-small cell lung cancer (NSCLC). The present invention also provides methods for determining drug resistance in NSCLC patients receiving EGFR inhibitor therapy.

Antibodies To Microbiome, Stress Factors And Mast Cell Markers As Diagnostic Markers For Ibs

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US Patent:
20150346200, Dec 3, 2015
Filed:
Mar 30, 2015
Appl. No.:
14/673660
Inventors:
- Vevey, CH
Nicholas Chi-Kwan Ling - San Diego CA, US
Fred Princen - La Jolla CA, US
Stefan Westin - Carlsbad CA, US
Steven Lockton - San Diego CA, US
Assignee:
NESTEC S.A. - Vevey
International Classification:
G01N 33/569
G01N 33/564
Abstract:
The present invention provides methods for aiding in the diagnosis of irritable bowel syndrome (IBS) in an individual. In particular, the present invention is useful for determining whether a sample from an individual is an IBS sample or a healthy control sample using a statistical algorithm. Thus, the present invention provides an accurate diagnostic prediction of IBS and is useful for guiding treatment decisions.

Methods For Improving Inflammatory Bowel Disease Diagnosis

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US Patent:
20150072879, Mar 12, 2015
Filed:
Mar 28, 2014
Appl. No.:
14/229715
Inventors:
- Vevey, CH
Steven Lockton - San Diego CA, US
Lisa J. Croner - San Diego CA, US
Frederick A. Fletcher - San Diego CA, US
Thomas Stockfisch - Escondido CA, US
Sharat Singh - Rancho Santa Fe CA, US
Assignee:
NESTEC S.A. - Vevey
International Classification:
G06F 19/00
G01N 33/543
C12Q 1/68
US Classification:
506 9, 435 611, 435 795, 435 794, 435 612, 702 19
Abstract:
The present invention provides methods and systems to predict and diagnose inflammatory bowel disease (IBD) and subtypes such as ulcerative colitis (UC) and Crohn's disease (CD) by detecting the presence, absence, level, and/or genotype of one or more sero-genetic-inflammation markers. Advantageously, with the present invention, it is possible to provide a diagnosis of IBD versus non-IBD, to rule out IBD that is inconclusive for CD and UC, and to differentiate between CD and UC with increased accuracy.
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Steven Lockton from San Diego, CA, age ~46 Get Report