Steven W Hansen

7496174, Feb 24, 2009

Jul 18, 2007

11/879901

Michael Gertner - Menlo Park CA, US
Steven D. Hansen - Concord CA, US
Erik Chell - Oakland CA, US

Oraya Therapeutics, Inc. - Newark CA

A61N 5/10

378 65, 378 68

A portable orthovoltage radiotherapy system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, the ocular structures are placed in a global coordinate system based on ocular imaging. In some embodiments, the ocular structures inside the global coordinate system lead to direction of an automated positioning system that is directed based on the ocular structures within the coordinate system.

7620147, Nov 17, 2009

Dec 13, 2007

11/956295

Michael Gertner - Menlo Park CA, US
Steven D. Hansen - Concord CA, US
Erik Chell - Oakland CA, US

Oraya Therapeutics, Inc. - Newark CA

A61N 5/10
G21K 1/02

378 65, 378145, 378147, 378205, 378206

A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, other disorders or tissues of a body are treated with the dose of radiation. In some embodiments, the target tissues are placed in a global coordinate system based on ocular imaging. In some embodiments, the target tissues inside the global coordinate system lead to direction of an automated positioning system that is directed based on the target tissues within the coordinate system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial marker is used to identify the location of the target tissues. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.

7680244, Mar 16, 2010

Oct 16, 2007

11/873386

Michael Gertner - Menlo Park CA, US
Erik Chell - Concord CA, US
Steven D. Hansen - Concord CA, US
Mark Arnoldussen - San Carlos CA, US
Matt Herron - Palo Alto CA, US
Kuang-Hung Pan - Mountain View CA, US

Oraya Therapeutics, Inc. - Newark CA

A61N 5/10

378 65

A radiosurgery system is described that delivers a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, ocular structures are placed in a global coordinate system, based on ocular imaging, which leads to direction of an automated positioning system. In some embodiments, the position of an ocular structure is tracked and related to a radiosurgery system. In some embodiments, a treatment plan is utilized for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial aids in positioning the system. In some embodiments, a reflection off the eye is used to aid in positioning. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.

7693260, Apr 6, 2010

Apr 9, 2008

12/100398

Michael Gertner - Menlo Park CA, US
Steven D. Hansen - Concord CA, US

Oraya Therapeutics, Inc. - Newark CA

A61N 5/10

378 65

A radiosurgery system is described that delivers a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, ocular structures are placed in a global coordinate system, based on ocular imaging, which leads to direction of an automated positioning system. In some embodiments, the position of an ocular structure is tracked and related to a radiosurgery system. In some embodiments, a treatment plan is utilized for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial aids in positioning the system. In some embodiments, a reflection off the eye is used to aid in positioning. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.

7792249, Sep 7, 2010

Dec 18, 2008

12/338634

Michael Gertner - Menlo Park CA, US
Mark Arnoldussen - San Carlos CA, US
Erik Chell - Oakland CA, US
Steven D. Hansen - Concord CA, US
Matt Herron - Redwood City CA, US
Igor Koruga - Pacifica CA, US
Junzhong Liang - Fremont CA, US

Oraya Therapeutics, Inc. - Newark CA

A61N 5/10

378 65, 606 4

Embodiments provide method and systems for determining alignment of a patient's body part, such as an eye, in an external coordinate system of a treatment or diagnostic device, such as a radiotherapy device, so as to define a reference axis for guiding device operation. Additional embodiments provide image-based methods and systems for aligning, tracking and monitoring motion of a body part and a treatment target in relation to a radiation beam axis. Particular ophthalmic embodiments provide method and systems including an eye-contact guide device and imaging system for aligning and tracking motion of an eye and ocular treatment target in relation to an orthovoltage X-ray beam axis, so as to monitor application of radiation to a lesion, such as a macular lesion of the retina. Particular methods for controlling radiation in response to motion of the target during treatment are described, such as algorithms for gating or interrupting radiation emission, both to ensure treatment goals and to avoid exposure to sensitive structures.

7801271, Sep 21, 2010

Oct 30, 2008

12/262031

Michael Gertner - Menlo Park CA, US
Mark Arnoldussen - San Carlos CA, US
Erik Chell - Oakland CA, US
Steven D. Hansen - Concord CA, US
Junzhong Liang - Fremont CA, US

Oraya Therapeutics, Inc. - Newark CA

A61N 5/10

378 65, 606 4

A method, code and system for planning the treatment a lesion on or adjacent to the retina of an eye of a patient are disclosed. There is first established at least two beam paths along which x-radiation is to be directed at the retinal lesion. Based on the known spectral and intensity characteristics of the beam, a total treatment time for irradiation along each beam paths is determined. From the coordinates of the optic nerve in the aligned eye position, there is determined the extent and duration of eye movement away from the aligned patient-eye position in a direction that moves the patient's optic nerve toward the irradiation beam that will be allowed during treatment, while still maintaining the radiation dose at the patient optic nerve below a predetermined dose level.

7912179, Mar 22, 2011

Jun 19, 2008

12/142718

Michael Gertner - Menlo Park CA, US
Steven D. Hansen - Concord CA, US
Erik Chell - Oakland CA, US
Matt Herron - Palo Alto CA, US

Oraya Therapeutics, Inc. - Newark CA

A61N 5/10

378 65

A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, other disorders or tissues of a body are treated with the dose of radiation. In some embodiments, the target tissues are placed in a global coordinate system based on ocular imaging. In some embodiments, the target tissues inside the global coordinate system lead to direction of an automated positioning system that is directed based on the target tissues within the coordinate system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial marker is used to identify the location of the target tissues. In some embodiments, an eye is held with force and in alignment with the system.

7953203, May 31, 2011

May 16, 2008

12/122640

Michael Gertner - Menlo Park CA, US
Steven D. Hansen - Concord CA, US
Erik Chell - Oakland CA, US

Oraya Therapeutics, Inc. - Newark CA

A61N 5/10

378 65

A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, other disorders or tissues of a body are treated with the dose of radiation. In some embodiments, the target tissues are placed in a global coordinate system based on ocular imaging. In some embodiments, the target tissues inside the global coordinate system lead to direction of an automated positioning system that is directed based on the target tissues within the coordinate system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial marker is used to identify the location of the target tissues. In some embodiments, an eye is held with force and in alignment with the system.