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Steven Govek Phones & Addresses

  • 13216 Via Santillana, San Diego, CA 92129 (858) 538-0902
  • Del Mar, CA
  • Irvine, CA
  • Asheville, NC
  • Stillwater, OK
  • Rochester, NY

Work

Company: Aragon pharmaceuticals, inc. Jul 2009 Position: Principal scientist

Education

Degree: Ph.D. School / High School: University of California, Irvine 1996 to 2002 Specialities: Organic Chemistry

Industries

Pharmaceuticals

Resumes

Resumes

Steven Govek Photo 1

Scientific Director, Chemistry

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Location:
San Diego, CA
Industry:
Pharmaceuticals
Work:
Aragon Pharmaceuticals, Inc. since Jul 2009
Principal Scientist

Kalypsys Jun 2005 - May 2009
Principal Scientist

Merck Research Laboratories Jun 2002 - May 2005
Senior Research Chemist
Education:
University of California, Irvine 1996 - 2002
Ph.D., Organic Chemistry

Publications

Us Patents

Benzoxazinyl-Amidocyclopentyl-Heterocyclic Modulators Of Chemokine Receptors

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US Patent:
7700591, Apr 20, 2010
Filed:
May 13, 2005
Appl. No.:
11/129512
Inventors:
Stephen D. Goble - Edison NJ, US
Sander G. Mills - Scotch Plains NJ, US
Lihu Yang - Edison NJ, US
Alexander Pasternak - Princeton NJ, US
Celine Bonnefous - San Diego CA, US
Theodore M Kamenecka - Palm Beach Gardens FL, US
Jean-Michel Vernier - Laguna Niguel CA, US
John H. Hutchinson - LaJolla CA, US
Essa Hu - Camarillo CA, US
Steven Govek - San Diego CA, US
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61K 31/535
C07D 265/12
C07D 498/00
US Classification:
5142295, 544 90
Abstract:
Cyclopentyl compounds linked to a benzoxazinyl group through an amido moiety utilizing the ring nitrogen of the benzoxazine, and further substituted with a heterocyclic moiety, such compounds represented by formula I:.

Bicyclic Heteroaryl Inhibitors Of Pde4

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US Patent:
7745646, Jun 29, 2010
Filed:
Jul 6, 2007
Appl. No.:
11/774058
Inventors:
Steven Govek - San Diego CA, US
Andrew K. Shiau - San Diego CA, US
Stewart A. Noble - San Diego CA, US
David J. Thomas - San Diego CA, US
Assignee:
Kalypsys, Inc. - San Diego CA
International Classification:
C07D 313/06
C07D 313/04
C07D 265/12
US Classification:
549268, 544 93, 549269, 549270, 549271
Abstract:
The present invention relates to compounds and methods which may be useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators.

Sulfonyl-Substituted Bicyclic Compounds As Modulators Of Ppar

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US Patent:
7834004, Nov 16, 2010
Filed:
Sep 4, 2008
Appl. No.:
12/204489
Inventors:
Stewart A. Noble - San Diego CA, US
Guy Oshiro - San Diego CA, US
James W. Malecha - San Diego CA, US
Cunxiang Zhao - San Diego CA, US
Carmen Robinson - San Diego CA, US
Sergio G. Duron - San Diego CA, US
Michael Sertic - Del Mar CA, US
Andrew K. Lindstrom - Encinitas CA, US
Andrew K. Shiau - San Diego CA, US
Christopher D Bayne - Honolulu HI, US
Mehmet Kahraman - San Diego CA, US
Boliang Lou - Louisville KY, US
Steven P. Govek - San Diego CA, US
Assignee:
Kalypsys, Inc - San Diego CA
International Classification:
A61K 31/496
A61K 31/343
A61K 31/404
A61K 31/551
A61K 31/495
C07D 333/52
C07D 403/02
C07D 209/04
C07D 405/02
C07D 307/78
US Classification:
514218, 51425213, 514414, 514415, 514443, 514469, 51425502, 51425301, 51425409, 544359, 544373, 544360, 548465, 548469, 549 49, 549462
Abstract:
Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.

Benzazole Potentiators Of Metabotropic Glutamate Receptors

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US Patent:
7960417, Jun 14, 2011
Filed:
Feb 17, 2006
Appl. No.:
11/884391
Inventors:
Steven P. Govek - San Diego CA, US
Jean-Michel Vernier - Laguna Niguel CA, US
Theodore Kamenecka - Palm Beach Gardens NJ, US
John H. Hutchinson - La Jolla CA, US
Richard Pracitto - North Wales PA, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
A61K 31/41
A61K 31/4192
C07D 403/12
C07D 249/20
C07D 249/18
US Classification:
514359, 514381, 548252, 548260
Abstract:
The present invention is directed to benzazole compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.

Bicyclic Heteroaryl Inhibitors Of Pde4

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US Patent:
8080563, Dec 20, 2011
Filed:
Jul 6, 2007
Appl. No.:
12/307730
Inventors:
Steven P. Govek - San Diego CA, US
Andrew K. Shiau - San Diego CA, US
Stewart A. Noble - San Diego CA, US
David J. Thomas - San Diego CA, US
Assignee:
Kalypsys - Del Mar CA
International Classification:
A61K 31/47
C07D 401/12
US Classification:
514312, 546157
Abstract:
The present invention relates to compounds and methods which may be useful as inhibitors of phosphodiesterase 4 (PD E4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators.

Heteroarylalkoxy-Substituted Quinolone Inhibitors Of Pde4

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US Patent:
8138205, Mar 20, 2012
Filed:
Aug 19, 2009
Appl. No.:
12/544185
Inventors:
Steven P. Govek - San Diego CA, US
Clay Beauregard - Fort Worth TX, US
Daniel A. Gamache - Arlington TX, US
Mark R. Hellberg - Arlington TX, US
Stewart A. Noble - San Diego CA, US
Andrew K. Shiau - San Diego CA, US
David J. Thomas - San Diego CA, US
John M. Yanni - Burleson TX, US
Assignee:
Kalypsys, Inc. - Del Mar CA
International Classification:
A61K 31/47
C07D 401/12
US Classification:
514312, 546157
Abstract:
The present invention relates to compounds and methods which may be useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators.

Bicyclic Heteroaryl Inhibitors Of Pde4

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US Patent:
8258154, Sep 4, 2012
Filed:
Jul 6, 2007
Appl. No.:
11/774053
Inventors:
Steven Govek - San Diego CA, US
Andrew K. Shiau - San Diego CA, US
Stewart A. Noble - San Diego CA, US
David J. Thomas - San Diego CA, US
Assignee:
Kalypsys Inc. - Solana CA
International Classification:
A61K 31/47
C07D 401/12
US Classification:
514312, 546157
Abstract:
The present invention relates to compounds and methods which may be useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators.

Estrogen Receptor Modulators And Uses Thereof

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US Patent:
8299112, Oct 30, 2012
Filed:
Sep 15, 2011
Appl. No.:
13/234035
Inventors:
Nicholas D. Smith - San Diego CA, US
Mehmet Kahraman - La Jolla CA, US
Steven P. Govek - San Diego CA, US
Johnny Y. Nagasawa - San Diego CA, US
Andiliy G. Lai - San Diego CA, US
Jackaline D. Julien - Del Mar CA, US
Celine Bonnefous - San Diego CA, US
Assignee:
Aragon Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 31/416
C07D 231/56
US Classification:
514406, 5483611
Abstract:
Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
Steven P Govek from San Diego, CA, age ~51 Get Report