Inventors:
Jingfang Q. Cutrone - Wallingford CT, US
Lyndon M. Foster - Oceanside CA, US
Kimberly D. Krampitz - Southington CT, US
Stephen W. Mamber - Pawtucket RI, US
Grace A. McClure - Northford CT, US
Todd C. Peterson - Coronado CA, US
Lisa C. Rupar - Woodbury CT, US
Katie A. Thompson - Milford IA, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C12P 7/62
A61K 35/66
A61K 35/74
US Classification:
435135, 424115, 424116, 560130, 4352535, 435108, 435170, 435 41
Abstract:
A novel tyrosyl diester antibiotic is obtained from fermentation of a recombinant strain of designated WD 15684 (ATCC-202143). The new antibiotic, designated tyrissamycin, exhibits antibacterial activity, particularly against gram-positive bacteria.