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Stephen G Haralampu

from Belmont, MA
Age ~69

Stephen Haralampu Phones & Addresses

  • 51 Washington St, Belmont, MA 02478 (617) 484-6121
  • Lampasas, TX
  • Plymouth, MA
  • Cambridge, MA
  • 51 Washington St, Belmont, MA 02478

Work

Company: Beta innovations llc Sep 2012 Position: Principal

Education

Degree: Doctorates, Doctor of Science School / High School: Massachusetts Institute of Technology 1979 to 1983 Specialities: Biology

Skills

R&D • Biotechnology • Commercialization • Technology Transfer • Lifesciences • Start Ups • Protein Chemistry • Product Development • Medical Devices • Biomarkers • Laboratory • Life Sciences • Drug Discovery • Pharmaceutical Industry • Hardware Diagnostics • Fda • Biochemistry • Process Simulation • Genomics • Assay Development • Manufacturing • Patents • Validation • Molecular Biology • Proteomics • Drug Development • Research and Development

Interests

Cooking • Exercise • Electronics • Aviation • Gardening • Home Improvement • Reading • Music • Sports • Movies • Home Decoration

Industries

Biotechnology

Resumes

Resumes

Stephen Haralampu Photo 1

Principal

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Location:
51 Washington St, Belmont, MA 02478
Industry:
Biotechnology
Work:
Beta Innovations Llc
Principal

Life Sciences Group Jun 2010 - Sep 2012
Co-Founder and Partner

Protein Forest, Inc. 2003 - 2010
Director, Rd and E

Haralampu Consulting 2001 - 2003
Principal

Opta Food Ingredients 1991 - 2000
Director, R and D
Education:
Massachusetts Institute of Technology 1979 - 1983
Doctorates, Doctor of Science, Biology
Massachusetts Institute of Technology 1977 - 1977
Massachusetts Institute of Technology 1973 - 1977
Skills:
R&D
Biotechnology
Commercialization
Technology Transfer
Lifesciences
Start Ups
Protein Chemistry
Product Development
Medical Devices
Biomarkers
Laboratory
Life Sciences
Drug Discovery
Pharmaceutical Industry
Hardware Diagnostics
Fda
Biochemistry
Process Simulation
Genomics
Assay Development
Manufacturing
Patents
Validation
Molecular Biology
Proteomics
Drug Development
Research and Development
Interests:
Cooking
Exercise
Electronics
Aviation
Gardening
Home Improvement
Reading
Music
Sports
Movies
Home Decoration

Business Records

Name / Title
Company / Classification
Phones & Addresses
Stephen G. Haralampu
Soc signatory
Beta Innovations LLC
Biotechnology
51 Washington St, Belmont, MA 02478
Stephen Haralampu
Treasurer
Life Sciences Group, Inc.
Biotechnology · Business Consulting Services · Nonclassifiable Establishments
51 Washington St, Belmont, MA 02478

Publications

Us Patents

Apparatus For Monitoring Tire Pressure

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US Patent:
7882732, Feb 8, 2011
Filed:
Apr 30, 2004
Appl. No.:
10/836321
Inventors:
Stephen George Haralampu - Belmont MA, US
Christopher Hume Reynolds - Wayland MA, US
David Vogel - Westwood MA, US
Jerrold Zindler - Brookline MA, US
International Classification:
B60C 23/02
US Classification:
731465
Abstract:
An apparatus for monitoring tire pressurization state in a tire has a magneto-mechanical pressure sensor in or on the tire and an electromagnetic excitation system. The electromagnetic excitation system is for interrogating the magneto-mechanical pressure sensor. The apparatus also has a receiver. The receiver is for receiving information from the electromagnetic excitation system. The apparatus also has a data interpretation system for translating the received information into the tire pressurization state. The data interpretation system is connected to a display. The display communicates the tire pressurization state to an operator.

Two-Dimensional Transfer Device

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US Patent:
20070209939, Sep 13, 2007
Filed:
Mar 10, 2006
Appl. No.:
11/372718
Inventors:
Stephen Haralampu - Belmont MA, US
William Skea - Saco ME, US
Mark Chlenov - Brighton MA, US
Edward Thompson - Hudson NH, US
International Classification:
C07K 1/26
G01N 27/00
US Classification:
204456000, 204606000
Abstract:
A system including apparatus and method of use that insures uniform contact and transfer of analytes from a first dimensional electrophoretic analytical gel to a second dimension, such as an electrophoretic analytical gel, has been developed. The device provides a means for transfer of analytes from a first dimension isoelectric focusing gel to a second dimension electrophoretic analytical gel. In a preferred embodiment, the device facilitates the transfer of protein analytes from a digital proteome chip to a second dimension electrophoretic analytical gel. The second dimension electrophoretic analytical gel can be for use with any technique known in the art, such as, but not limited to SDS-PAGE molecular weight analysis, secondary isoelectric focusing, and capillary electrophoresis. The main features of the system are a mechanical device that locates the first dimension analysis at a fixed and known position in space, and a low density medium that assures uniform electrical contact between the first and second dimension analyses. The advantage of an apparatus that places the first dimension in a known position is that the final data analysis is greatly facilitated by precisely knowing the locations of the first dimension pH features. The medium that assures electrical contact also has the advantage of simplifying the final data analysis by assuring a uniform frame of reference on how the second dimension analysis was run.

System And Method For Proteomics

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US Patent:
20080272002, Nov 6, 2008
Filed:
May 3, 2007
Appl. No.:
11/744060
Inventors:
Jack Johansen - Concord MA, US
Russell K. Garlick - Needham MA, US
William Skea - Saco ME, US
Stephen Haralampu - Belmont MA, US
Oren Kagan - Chestnut Hill MA, US
International Classification:
G01F 1/64
US Classification:
204456
Abstract:
Significantly higher yield and better resolution in pI gels are obtained by creating traps having two or more layers of gel containing closely stepped immobilized pH buffers. Proteins move from a pH at which they are negatively charged towards an anode at which they are positively charged. Discrete regions containing immobilized pH buffers trap the proteins when the immobilized buffer pH and the protein pI are approximately the same. The protein is trapped within the second layer and not on the surface of or interface of the second layer. Significantly higher yields with better resolution can be obtained through the use of layered sample application gels prior to isoelectric focusing. Layered plugs are prepared with a range of immobilized pH buffers ranging, for example, over 2 pH units, with steps of 0.05 or 0.1 pH units. An array of multilayered plugs wherein each plug has different pH increments is also provided. The array can be used to isolate and trap a variety of proteins having different isoelectric pHs during a single run. Another embodiment provides plugs having at least three layers; a gate layer, a trap layer, and an exit layer. Another embodiment includes adding a carrier ampholytes to running buffers and or adding thiol containing reducing agents to reduce current and improve resolution and collection efficiency.

Stopped-Flow, Micro-Fluidic Device And Method For The Charge-Based Separation Of Complex Analyte Mixtures

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US Patent:
20130153422, Jun 20, 2013
Filed:
Nov 20, 2012
Appl. No.:
13/682430
Inventors:
Stephen G. Haralampu - Belmont MA, US
International Classification:
G01N 27/447
B81B 1/00
US Classification:
204548, 204644
Abstract:
The present inventions relate to micro-fluidic devices and related methods of fractionating samples of analytes, such as peptides or proteins, according to their isoelectric points. The disclosed micro-fluidic devices and related methods provide a fractionation sufficient to enhance the performance of immunochemistry and/or tandem liquid chromatography-mass spectrometry workflows. Such methods and devices are capable of fractionating complex samples in a short time, using a small amount of sample, do not require high voltages and are further characterized by their high degree of reproducibility and ease of use.

Granular Resistant Starch And Method Of Making

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US Patent:
58490906, Dec 15, 1998
Filed:
Mar 27, 1996
Appl. No.:
8/622844
Inventors:
Stephen G. Haralampu - Plymouth MA
Akiva Gross - Newton MA
Assignee:
Opta Food Ingredients, Inc. - Bedford MA
International Classification:
C08B 3000
C08B 3012
A23L 105
US Classification:
127 65
Abstract:
A method of producing a granular resistant starch comprising the steps of heating a granular native starch to swell but not rupture the starch granules, debranching the starch, treating the starch to retrograde the amylose therein, optionally annealing the starch and optionally drying the product to a powder is described. Granular resistant starch produced by this method and food formulations containing the granular resistant starch are also described.

Method Of Coating Foods With An Edible Oil Barrier Film And Product Thereof

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US Patent:
51261529, Jun 30, 1992
Filed:
Mar 1, 1991
Appl. No.:
7/663411
Inventors:
Robert D. Feeney - Scituate MA
Stephen G. Haralampu - Plymouth MA
Akiva Gross - Newton MA
Assignee:
Opta Food Ingredients, Inc. - Cambridge MA
International Classification:
A23L 1217
US Classification:
426102
Abstract:
A method is described for reducing the amount of oil absorbed into a food during hot oil frying. The method involves coating the food, prior to deep fat frying with a protein latex which forms a layer of hydrophobic protein having excellent barrier properties to hot oil.

Microcrystalline Starch-Based Product And Use In Foods

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US Patent:
59620471, Oct 5, 1999
Filed:
Jun 14, 1996
Appl. No.:
8/665082
Inventors:
Akiva Gross - Newton MA
Stephen G. Haralampu - Plymouth MA
Assignee:
Opta Food Ingredients, Inc. - Bedford MA
International Classification:
A23L 1076
US Classification:
426 48
Abstract:
A microcrystalline starch-based product comprising microcrystalline starch, glucose and short chain glucooligosaccharides and having an average particle size of less than about 10. mu. , and a process for making the microcrystalline starch-based product consisting of optionally debranching, retrograding and hydrolyzing a starch are disclosed. Also disclosed are food formulations comprising the microcrystalline resistant starch-based product.

Process For Producing Compacted, Dehydrated, Uncooked Cabbage And Cabbage Product Thereof

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US Patent:
41090268, Aug 22, 1978
Filed:
Jul 25, 1977
Appl. No.:
5/818701
Inventors:
Abdul R. Rahman - Natick MA
Stephen G. Haralampu - Belmont MA
Assignee:
The United States of America as represented by the Secretary of the Army - Washington DC
International Classification:
A23B 702
A23B 706
A23B 714
US Classification:
426640
Abstract:
A process for producing compacted, dehydrated, uncooked cabbage of increa density comprising subdividing fresh cabbage, treating the subdivided cabbage with aqueous sodium metabisulfite solution, removing the excess sodium metabisulfite solution, hot air blanching the cabbage, partially dehydrating the cabbage with heated air until its moisture content is reduced to about 5-8 percent by weight, partially rehydrating the cabbage to a moisture content of about 10 to 20 percent by weight with an aqueous solution of a food grade surface-active agent, equilibrating the solution of surface-active agent throughout the cabbage, compressing the partially rehydrated cabbage at a pressure of about 50 to 200 psi to obtain a compression ratio of about 7:1 to 15:1, redrying the compressed cabbage with heated air at about 55. degree. to 65. degree. C. until the moisture content thereof is reduced to no greater than 5% by weight, and packaging the compressed, dehydrated, uncooked cabbage in a hermetically sealed, moisture-proof container. Also, the compacted, dehydrated, uncooked cabbage obtained by the process described.
Stephen G Haralampu from Belmont, MA, age ~69 Get Report