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Srinivasan Ramanathan

from San Jose, CA
Age ~52

Srinivasan Ramanathan Phones & Addresses

  • San Jose, CA
  • Potsdam, NY
  • Penn Yan, NY

Publications

Us Patents

Enhanced Oral And Transcompartmental Delivery Of Therapeutic Or Diagnostic Agents

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US Patent:
20030091640, May 15, 2003
Filed:
Feb 8, 2002
Appl. No.:
10/072657
Inventors:
Srinivasan Ramanathan - Mountain View CA, US
Stanley Stein - East Brunswick NJ, US
Michael Leibowitz - Manalapan NJ, US
Patrick Sinko - Lebanon NJ, US
Tamara Minko - Edison NJ, US
Gregory Williams - Warren NJ, US
Xiaoping Zhang - Piscataway NJ, US
Shahrair Pooyan - Monnt Kisco NY, US
Seong Park - Piscataway NJ, US
Bo Qiu - East Brunswick NJ, US
Pankaj Paranjpe - Piscataway NJ, US
International Classification:
A61K009/14
US Classification:
424/486000
Abstract:
The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.

Enhanced Oral And Transcompartmental Delivery Of Therapeutic Or Diagnostic Agents

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US Patent:
20060029667, Feb 9, 2006
Filed:
Jun 29, 2005
Appl. No.:
11/170652
Inventors:
Srinivasan Ramanathan - Mountain View CA, US
Stanley Stein - East Brunswick NJ, US
Michael Leibowitz - Manalapan NJ, US
Patrick Sinko - Lebanon NJ, US
Tamara Minko - Edison NJ, US
Gregory Williams - Warren NJ, US
Xiaoping Zhang - Piscataway NJ, US
Shahrair Pooyan - Monnt Kisco NY, US
Seong Park - Piscataway NJ, US
Bo Qiu - East Brunswick NJ, US
Pankaj Paranjpe - Piscataway NJ, US
International Classification:
A61K 9/20
US Classification:
424465000
Abstract:
The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.

Therapeutic Compositions And The Use Thereof

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US Patent:
20100331331, Dec 30, 2010
Filed:
Jun 26, 2008
Appl. No.:
12/666991
Inventors:
Brian P. Kearney - Foster City CA, US
Anita A. Mathias - Foster City CA, US
Srinivasan Ramanathan - Foster City CA, US
Assignee:
ThERAPEUTIC COMPOSITONS AND USE THEREOF - FORSTER CITY
International Classification:
A61K 31/5377
A61K 31/47
A61P 31/12
US Classification:
5142368, 514312
Abstract:
The invention includes methods, compositions, and kits useful for treating a viral infection by administering 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof, with atazanavir or a pharmaceutically acceptable salt thereof, and optionally with a compound that inhibits cytochrome P-450, or a pharmaceutically acceptable salt thereof.

Enhanced Oral Transcompartmental Delivery Of Therapeutic Or Diagnostic Agents

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US Patent:
20110087004, Apr 14, 2011
Filed:
Jun 18, 2010
Appl. No.:
12/818955
Inventors:
Srinivasan Ramanathan - Mountain View CA, US
Stanley Stein - East Brunswick NJ, US
Michael Leibowitz - Manalapan NJ, US
Patrick J. Sinko - Lebanon NJ, US
Tamara Minko - Edison NJ, US
Gregory C. Williams - Warren NJ, US
Xiaoping Zhang - Piscataway NJ, US
Shahrair Pooyan - Mount Kisco NJ, US
Seong Hee Park - Piscataway NJ, US
Bo Qiu - East Brunswick NJ, US
Pankaj Paranjpe - Piscataway NJ, US
International Classification:
C07K 7/06
US Classification:
530327
Abstract:
The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.

Enhanced Oral Transcompartmental Delivery Of Therapeutic Or Diaganostic Agents

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US Patent:
20130072447, Mar 21, 2013
Filed:
May 14, 2012
Appl. No.:
13/471083
Inventors:
Srinivasan Ramanathan - Mountain View CA, US
Stanley Stein - East Brunswick NJ, US
Michael Leibowitz - Manalapan NJ, US
Patrick J. Sinko - Annandale NJ, US
Tamara Minko - Edison NJ, US
Gregory C. Williams - Warren NJ, US
Xiaoping Zhang - Piscataway NJ, US
Shahrair Pooyan - Mount Kisco NY, US
Seong Hee Park - Piscataway NJ, US
Bo Qiu - Clinton NJ, US
Pankaj Paranjpe - Piscataway NJ, US
Assignee:
Rutgers, The State University of New Jersey - New Brunswick NJ
International Classification:
A61K 47/48
A61K 38/08
A61K 47/34
US Classification:
514 215, 514 219
Abstract:
The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.

Combination Therapies For Treating B-Cell Malignancies

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US Patent:
20180353512, Dec 13, 2018
Filed:
Jun 22, 2016
Appl. No.:
15/739049
Inventors:
- Foster City CA, US
- Osaka, JP
Kathy Keegan - Foster City CA, US
Ryohei Kozaki - Osaka, JP
Sarah Meadows - Foster City CA, US
Cara Nelson - Foster City CA, US
Christophe Queva - Braine L'alleud, BE
Srinivasan Ramanathan - Foster City CA, US
Stacey Tannheimer - Foster City CA, US
Daniel Tumas - Foster City CA, US
Tomoko Yasuhiro - Osaka, JP
Toshio Yoshizawa - Osaka, JP
International Classification:
A61K 31/522
A61K 31/52
A61P 35/00
Abstract:
Provided herein are methods that relate to a therapeutic strategy for treatment of a B-cell malignancy. In particular, the methods include administration of a PI3K inhibitor and a BTK inhibitor.

Method Of Treating A Viral Infection Using Elvitegravir Combinations

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US Patent:
20170136001, May 18, 2017
Filed:
Oct 19, 2016
Appl. No.:
15/298084
Inventors:
- Foster City CA, US
Anita A. MATHIAS - Sunnyvale CA, US
Srinivasan RAMANATHAN - San Carlos CA, US
International Classification:
A61K 31/47
A61K 31/5377
A61K 31/4402
A61K 31/426
Abstract:
The invention includes methods, compositions, and kits useful for treating a viral infection by administering 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof, with atazanavir or a pharmaceutically acceptable salt thereof, and optionally with a compound that inhibits cytochrome P-450, or a pharmaceutically acceptable salt thereof.

Combination Therapy Comprising Tenofovir Alafenamide Hemifumarate And Cobicistat For Use In The Treatment Of Viral Infections

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US Patent:
20170056423, Mar 2, 2017
Filed:
Oct 3, 2016
Appl. No.:
15/284105
Inventors:
- Foster City CA, US
Srinivasan RAMANATHAN - San Carlos CA, US
International Classification:
A61K 31/675
A61K 31/513
A61K 31/47
A61K 31/5377
Abstract:
The use of the hemifumarate form of {9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycarbonyl)ethyl]amino]phenoxyphosphinyl]methoxy]propyl]adenine} (tenofovir alafenamide hemifumarate) in combination with cobicistat is disclosed. In addition, the combination of tenofovir alafenamide hemifumarate, cobicistat, emtricitabine, and elvitegravir, and the combination of tenofovir alafenamide hemifumarate, cobicistat, emtricitabine, and darunavir, are disclosed.
Srinivasan Ramanathan from San Jose, CA, age ~52 Get Report