Smita Abbi Phones & Addresses
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19 Ridge Rd, Dunellen, NJ 08812
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Green Brook, NJ
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South Plainfield, NJ
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Mechanicsburg, PA
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Jersey City, NJ
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Ithaca, NY
Publications
Us Patents
Methods Of Regulating Focal Adhesion Kinase And Its Associated Cellular Functions By Fak Family-Interacting Protein
View pageUS Patent:
20050037963, Feb 17, 2005
Filed:
Jul 8, 2004
Appl. No.:
10/886744
Inventors:
Smita Abbi - South Plainfield NJ, US
International Classification:
A61K038/17
US Classification:
514012000
Abstract:
The present invention is directed to treating a subject suffering from a disorder mediated by cell proliferation, such as cancer, by administering a fragment of focal adhesion kinase family kinase-interacting proteins. This method can involve regulating tumor formation or tumor growth in the subject. In addition, the present invention relates to the use of these proteins for regulating G1 to S phase progression of a cell, regulating the expression of p21 in a cell, regulating the phosphorylation of retinoblastoma protein in a cell, regulating retinoblastoma protein/E2F transcription factor 1 complex formation in a cell, regulating detachment-induced apoptosis of a cell, and regulating anchorage-independent growth of a cell.