Inventors:
Phillip Tarr - Seattle WA, US
Sima Bilge - Bellevue WA, US
Thomas Besser - Moscow ID, US
James Vary - Seattle WA, US
International Classification:
A61K039/00
A61K039/38
Abstract:
Polypeptides encoded by a continuous segment of chromosomal DNA from O157:H7, isolated on plasmid pSC(overlap)(ATCC No. 69648), that encodes an adhesin (SEQ ID NO:5) that mediates bacterial colonization of bovine intestines, vaccines derived therefrom, and antibodies directed against the adhesin are disclosed.