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Silviu M Itescu

from New York, NY
Age ~67
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Also known as:
Itescu S Dr, U U
Phone and address:
279 44Th St, New York, NY 10017
(212) 986-4266
Related to:
David Itescu
Connected to:
Audrey F Itf, 81Ramazan K Itf, 53Heng Ith, 60Trent R Ith, 56Albert J Ithen, 53Angela M Ithier, 41Luke W Ithomitis, 40Daniel P Ithurburn, 38Ricky P Itibus, 39Janel C Itin, 65

Silviu Itescu Phones & Addresses

  • 279 44Th St, New York, NY 10017 (212) 986-4266
  • Fair Lawn, NJ

Work

Address: 177 Fort Washington Ave, New York, NY 10032 Specialities: Internist

Education

School / High School: University of Melbourne / Faculty of Medicine

Languages

English

Awards

Healthgrades Honor Roll

Ranks

Certificate: Internal Medicine, 1986

Specialities

Rheumatology

Professional Records

Medicine Doctors

Silviu Itescu Photo 1

Dr. Silviu Itescu, New York NY - MD (Doctor of Medicine)

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Specialties:
Rheumatology
Address:
177 Fort Washington Ave Suite 7-435, New York, NY 10032
(201) 346-7052 (Phone), (201) 346-7049 (Fax)
Certifications:
Internal Medicine, 1986
Rheumatology, 1990
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
University of Melbourne / Faculty of Medicine
Medical School
Alfred Hosp
Medical School
Bellevue Hospital Center
Medical School
Metropolitan Hospital Center
Silviu Itescu Photo 2

Silviu Itescu, New York NY

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Specialties:
Internist
Address:
177 Fort Washington Ave, New York, NY 10032
275 Madison Ave, New York, NY 10016
Education:
University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences - Doctor of Medicine
Bellevue Hospital Center - Residency - Internal Medicine
Metropolitan Hospital Center - Residency - Internal Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine

Resumes

Resumes

Silviu Itescu Photo 3

Associate Professor

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Location:
New York, NY
Industry:
Biotechnology
Work:
Columbia University In the City of New York
Associate Professor
Silviu Itescu Photo 4

Director

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Location:
New York, NY
Industry:
Biotechnology
Work:
Mesoblast Limited
Founder
Mesoblast Limited
Director
Silviu Itescu Photo 5

Founder At Mesoblast

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Position:
founder at mesoblast
Location:
Greater New York City Area
Industry:
Alternative Medicine
Work:
mesoblast
founder

Business Records

Name / Title
Company / Classification
Phones & Addresses
Silviu Itescu
Scientific Founder Chairman Of Scientific Advisory Board Chief Scientist And Director
Angioblast Systems, Inc.
275 Madison Ave FL 4, New York, NY 10016
(212) 880-2060
Silviu Itescu
Silviu Itescu MD
Allergist · Internist
177 Ft Washington Ave, New York, NY 10032
(201) 447-8717
Silviu Itescu
MESOBLAST, INC
505 5 Ave FL 3, New York, NY 10017
505 5 Ave Level 3, New York, NY 10017

Publications

Us Patents

Use Of Sdf-1 Or G-Csf To Improve Myocardial Function After Ischemic Injury

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US Patent:
7662392, Feb 16, 2010
Filed:
Sep 22, 2005
Appl. No.:
11/234879
Inventors:
Silviu Itescu - New York NY, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
A61K 38/18
A61K 38/16
C07K 14/475
US Classification:
4241981, 4241841, 514 2, 514 12, 530399
Abstract:
This invention provides methods of improving myocardial function in a subject after ischemic injury comprising administering G-CSF or SDF-1 to the subject.

Dna Enzyme To Inhibit Plasminogen Activator Inhibitor-1

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US Patent:
7662794, Feb 16, 2010
Filed:
Apr 23, 2003
Appl. No.:
10/512496
Inventors:
Silviu Itescu - New York NY, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
C07H 21/04
A01N 43/04
A61K 31/70
US Classification:
514 44, 536 231, 536 243, 536 2433, 536 245
Abstract:
The present invention provides DNAzymes and ribozymes that specifically cleave PAI-1-encoding mRNA. The present invention also provides antisense oligonucleotides that specifically inhibit translation of PAI-1-encoding mRNA. The invention also provides various methods of inhibiting the expression of PAI-1, and methods of treating diseases by such. Finally the invention provides pharmaceutical compositions containing the instant DNAzymes, ribozymes, antisense oligonucleotides, or other inhibitors of PAI-1 expression as active ingredients.

Method Of Inhibiting Collagen Formation By Vdup1 Inhibition

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US Patent:
7887796, Feb 15, 2011
Filed:
Apr 23, 2003
Appl. No.:
10/512518
Inventors:
Silviu Itescu - New York NY, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
A61K 38/16
A61K 31/7084
A61K 31/7088
A61K 39/395
C07K 14/435
C07K 16/00
C07H 21/02
C07H 21/04
US Classification:
4241301, 530350, 5303871, 536 231, 514 2, 514 12, 514 44
Abstract:
This invention provides a method of treating a disorder of a subject's heart involving loss of cardiomyocytes which comprises administering to the subject an amount of an agent effective to cause cardiomyocyte proliferation within the subject's heart so as to thereby treat the disorder. This invention further provides the instant method wherein the agent is human endothelial progenitor cells, G-CSF, GM-CSF, SDF-1, and IL-8. This invention also provides methods of determining the susceptibility of a cardiomyocyte in a subject to apoptosis.

Method Of Increasing Trafficking Of Endothelial Progenitor Cells To Ischemia-Damaged Tissue

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US Patent:
8153113, Apr 10, 2012
Filed:
Aug 20, 2007
Appl. No.:
11/894581
Inventors:
Silviu Itescu - New York NY, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
A61K 38/20
C07K 14/54
US Classification:
424 852, 530351
Abstract:
This invention provides a method of increasing trafficking of endothelial progenitor cells to ischemia-damaged tissue in a subject comprising administering to the subject an amount of interleukin-8 effective to attract endothelial progenitor cells to the ischemia-damaged tissue.

Treatment Of Tumor With Dnazyme Directed To Peroxiredoxin

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US Patent:
8242091, Aug 14, 2012
Filed:
Dec 29, 2006
Appl. No.:
11/648769
Inventors:
Silviu Itescu - New York NY, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
C07H 21/04
A01N 43/04
A61K 31/70
US Classification:
514 44, 536 231, 536 243, 536 245
Abstract:
This invention provides a method of treating a disorder of a subject's heart involving loss of cardiomyocytes which comprises administering to the subject an amount of an agent effective to cause cardiomyocyte proliferation within the subject's heart so as to thereby treat the disorder. This invention further provides the instant method wherein the agent is human endothelial progenitor cells, G-CSF, GM-CSF, SDF-1, and IL-8. This invention also provides methods of determining the susceptibility of a cardiomyocyte in a subject to apoptosis.

Use Of Sdf-1 To Improve Ischemic Myocardial Function

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US Patent:
8486416, Jul 16, 2013
Filed:
Jan 15, 2010
Appl. No.:
12/657264
Inventors:
Silviu Itescu - New York NY, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
A61K 38/16
A61K 38/18
C07K 14/475
US Classification:
4241981, 514 164, 514 213, 530300, 530399
Abstract:
A method is provided for increasing trafficking of endothelial progenitor cells to an ischemic myocardium in a subject's heart comprising administering to the subject's heart an amount of Stromal-Derived Factor-1 (SDF-1).

Dna Enzyme To Inhibit Plasminogen Activator Inhibitor-1

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US Patent:
20030199463, Oct 23, 2003
Filed:
Apr 23, 2002
Appl. No.:
10/128706
Inventors:
Silviu Itescu - New York NY, US
International Classification:
A61K048/00
C07H021/02
US Classification:
514/044000, 536/023100
Abstract:
The present invention provides DNAzymes and ribozymes that specifically cleave PAI-1-encoding mRNA. The present invention also provides antisense oligonucleotides that specifically inhibit translation of PAI-1-encoding mRNA. The invention also provides various methods of inhibiting the expression of PAI-1. Finally the invention provides pharmaceutical compositions containing the instant DNAzymes, ribozymes and antisense oligonucleotides as active ingredients.

Regeneration Of Endogenous Myocardial Tissue By Induction Of Neovascularization

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US Patent:
20030199464, Oct 23, 2003
Filed:
Apr 23, 2002
Appl. No.:
10/128738
Inventors:
Silviu Itescu - New York NY, US
International Classification:
A61K048/00
US Classification:
514/044000
Abstract:
This invention provides a method of treating a disorder of a subject's heart involving loss of cardiomyocytes which comprises administering to the subject an amount of an agent effective to cause cardiomyocyte proliferation within the subject's heart so as to thereby treat the disorder. This invention further provides the instant method wherein the agent is human endothelial progenitor cells. This invention also provides methods of determining the susceptibility of a cardiomyocyte in a subject to apoptosis.
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Silviu M Itescu from New York, NY, age ~67 Get Report