US Patent:
20190382800, Dec 19, 2019
Inventors:
- Cambridge MA, US
- New Brunswick NJ, US
- Moscow, RU
- Bethesda MD, US
Kira S. Makarova - Bethesda MD, US
Eugene Koonin - Bethesda MD, US
Silvana Konermann - Cambridge MA, US
Julia Joung - Cambridge MA, US
Jonathan S. Gootenberg - Cambridge MA, US
Omar O. Abudayyeh - Cambridge MA, US
Eric S. Lander - Cambridge MA, US
International Classification:
C12N 15/90
C12N 15/113
C12N 15/85
C12N 15/82
C12N 15/11
C12N 9/22
C12N 15/10
Abstract:
The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.