Inventors:
Stephen T. Wrobleski - Flemington NJ, US
Jagabandhu Das - Mercerville NJ, US
Lidia M. Doweyko - Vero Beach FL, US
Junqing Guo - Princeton NJ, US
John Hynes - Washington Crossing PA, US
Bin Jiang - Norristown PA, US
James Kempson - Princeton NJ, US
Shuqun Lin - Newtown PA, US
Steven H. Spergel - Warrington PA, US
John S. Tokarski - Princeton NJ, US
Hong Wu - New Hope PA, US
Bingwei Vera Yang - Belle Mead NJ, US
International Classification:
C07D 487/04
C07F 9/6561
US Classification:
514 80, 5142308, 544119, 514248, 544235, 540200, 51421002, 5142285, 544 582, 5142332, 544232
Abstract:
Disclosed are compounds of formula (I) and pharmaceutically acceptable salts thereof. The compounds of formula (I) inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.