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Shuan Dong Dong

from Chappaqua, NY
Age ~59

Shuan Dong Phones & Addresses

  • 364 N Greeley Ave, Chappaqua, NY 10514
  • 14202 Crystal Ridge Dr, Watchung, NJ 07069 (908) 822-8712
  • 14302 Crystal Ridge Dr, Watchung, NJ 07069 (908) 822-8712
  • Union, NJ

Publications

Us Patents

Preparation Of 3-Amino-3-(Cyclobutylmethyl)-2-(Hydroxy)-Propionamide Hydrochloride

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US Patent:
20100113821, May 6, 2010
Filed:
Dec 17, 2007
Appl. No.:
12/519486
Inventors:
Jeonghan Park - Whippany NJ, US
Eugene J. Vater - Lyndhurst NJ, US
Shuan Dong - Watchung NJ, US
Tetsuo Iwama - Scotch Plains NJ, US
Ramani R. Raghavan - Lexington MA, US
Hong-Chang Lee - Livingston NJ, US
George S.k. Wong - Summit NJ, US
Assignee:
Schering-Plough Corporation - Kenilworth NJ
International Classification:
C07C 69/74
C07C 229/02
C07C 237/14
C07C 205/15
C07C 205/02
US Classification:
560123, 562505, 564191, 568704, 568924
Abstract:
Disclosed is a process for preparing 3-(amino)-3-cyclobutylmethyl-2-hydroxy-propionamide hydrochloride, an intermediate useful in the preparation of the HCV protease inhibitor (1R,5S)—N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide.

Process For The Synthesis Of 3- Amino-3-Cyclobuthylmethyl-2-Hydroxypropionamide Or Salts Thereof

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US Patent:
20110034705, Feb 10, 2011
Filed:
Dec 17, 2008
Appl. No.:
12/809775
Inventors:
Shuan Dong - Watchung NJ, US
Jeonghan Park - Whippany NJ, US
Eugene John Vater - Lyndhurst NJ, US
Assignee:
Schering-Plough Corporation - Kenilworth NJ
International Classification:
C07D 209/52
C07C 231/06
US Classification:
548515, 564130
Abstract:
A process for preparing 3-amino-3-cyclobutylmethyl-2-hydroxypropionamide of the Formula I:or a salt thereof involves providing a compound of the Formula VI described herein in a solution comprising predominately dimethylsulfoxide (DMSO) and converting this compound directly to the compound of the Formula VIII described herein without working up or isolating the intermediate compound of the Formula VII described herein.
Shuan Dong Dong from Chappaqua, NY, age ~59 Get Report