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Shizhong Chen

from San Diego, CA
Age ~63
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Also known as:
Zhong Chen, Zhong Chen Shi, Shizong Cheng, Chen Shizhong
Phone and address:
12018 Medoc Ln, San Diego, CA 92131
Related to:
Jie Chen, 69Shuibing Chen, 46Geoffrey A Chang, 54Zhongzhong Chen, 55Qiang ChenQiang Chen, 69Zhongguo Chen, 81Chuan Chen Liangjing, 62Fengcheng Cheng Xia, 64Chen Gang, 47Dawei W Chen, 55Chea QuigeLu Chen, 38Wen ChenKunsheng Chen, 41
Connected to:
Abre G Chen, 65Adele Chen, 52Adeline K Chen, 39Ai M Chen, 60Ai C Chen, 79Aiping Chen, 63Alen Y Chen, 68Alma Chen, 29Amanda Chen, 44Amanda T Chen, 63

Shizhong Chen Phones & Addresses

  • 12018 Medoc Ln, San Diego, CA 92131
  • 11921 Carmel Creek Rd, San Diego, CA 92130
  • 10485 Spruce Grove Ave, San Diego, CA 92131
  • Escondido, CA

Work

Company: Genestitute 2008 Position: President

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Uc San Diego 1983 to 1991 Specialities: Molecular Biology

Skills

Molecular Biology • Protein Engineering • Bioinformatics • Biotechnology • Mutagenesis • Lifesciences • Biochemistry • Assay Development • Immunology • Drug Discovery • Biomarkers • Biopharmaceuticals

Industries

Biotechnology

Resumes

Resumes

Shizhong Chen Photo 1

President

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Location:
San Diego, CA
Industry:
Biotechnology
Work:
Genestitute
President
Johnson & Johnson 2005 - 2007
Director of Molecular Biology and Bioinformatics
Egea Biosciences 2002 - 2006
Director of Molecular Biology
Independent Federation of Chinese Students and Scholars 2000 - 2001
Vice President
Gene Therapy Systems 1999 - 2001
Consultant
Education:
Uc San Diego 1983 - 1991
Doctorates, Doctor of Philosophy, Molecular Biology University of Science and Technology of China 1978 - 1981
Bachelors, Bachelor of Science, Biology
Skills:
Molecular Biology
Protein Engineering
Bioinformatics
Biotechnology
Mutagenesis
Lifesciences
Biochemistry
Assay Development
Immunology
Drug Discovery
Biomarkers
Biopharmaceuticals

Business Records

Name / Title
Company / Classification
Phones & Addresses
Shizhong Chen
President
THE CONSCIENCE FOUNDATION
Services-Misc
3186 Adams Ave SUITE 202, San Diego, CA 92116
(619) 280-5177

Publications

Us Patents

Diagnostic And Therapeutic Methods Related To Regulating Energy Mobilization With Ob Protein And Ob Antibodies

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US Patent:
7067472, Jun 27, 2006
Filed:
Jun 4, 1997
Appl. No.:
09/194889
Inventors:
Lili Feng - San Diego CA, US
Shizhong Chen - San Diego CA, US
Yiyang Xia - San Diego CA, US
Assignee:
The Scripps Research Institute - La Jolla CA
International Classification:
A01N 38/00
A61K 39/00
C07K 14/00
US Classification:
514 2, 4241981, 530351
Abstract:
Compositions comprising OB-R agonists and methods of treatment for conditions such as systemic inflammatory response syndrome are provided. One suitable OB-R agonist ligand is recombinant human OB protein, also known as leptin. Also provided are methods and compositions for the treatment of obesity and OB resistance. Assay methods and kits relating to these conditions are also included.

Methods For Use In Human-Adapting Monoclonal Antibodies

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US Patent:
8093068, Jan 10, 2012
Filed:
Oct 25, 2007
Appl. No.:
11/924094
Inventors:
Shizhong Chen - San Diego CA, US
Shanrong Zhao - San Diego CA, US
Assignee:
Centocor, Inc. - Malvern PA
International Classification:
G01N 33/536
G01N 33/531
C07K 16/00
US Classification:
436536, 436543, 5303871
Abstract:
Methods useful for human adapting non-human monoclonal antibodies are disclosed. The methods select candidate human antibody framework sequences from a human germline framework database.

Toll Like Receptor 3 Antagonists, Methods And Uses

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US Patent:
8153583, Apr 10, 2012
Filed:
Nov 30, 2005
Appl. No.:
11/291140
Inventors:
Jill M. Carton - Malvern PA, US
Shizhong Chen - San Diego CA, US
Mark Cunningham - Kennett Square PA, US
Anuk Das - Wayne PA, US
Karen Duffy - Trappe PA, US
Theresa J. Goletz - King of Prussia PA, US
David M. Knight - Berwyn PA, US
Roberta Lamb - Wynnewood PA, US
Mouhamadou L. Mbow - King of Prussia PA, US
Kristen Picha - Malvern PA, US
Gopalan Raghunathan - San Diego CA, US
Lani San Mateo - Devon PA, US
Robert T. Sarisky - Lansdale PA, US
Nicole Stowell - Havertown PA, US
Raymond Sweet - Bryn Mawr PA, US
Shanrong Zhao - San Diego CA, US
International Classification:
A61K 38/00
C07K 16/00
US Classification:
514 14, 514 69, 514 122, 5303871, 5303873, 5303881, 53038815
Abstract:
Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists, and methods of making and using the foregoing are disclosed.

Fast And Enzymeless Cloning Of Nucleic Acid Fragments

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US Patent:
20020165175, Nov 7, 2002
Filed:
Apr 17, 2001
Appl. No.:
09/836436
Inventors:
Xiaowu Liang - La Jolla CA, US
Andy Teng - Fullerton CA, US
Shizhong Chen - San Diego CA, US
Dongyuan Xia - Powell OH, US
Philip Felgner - Rancho Santa Fe CA, US
International Classification:
C12Q001/68
A61K048/00
C12P019/34
C12N015/86
US Classification:
514/044000, 435/455000, 435/456000, 435/091200, 435/006000
Abstract:
A method for cloning a nucleic acid fragment into a vector by flanking the fragment with first and second adapter sequences, and contacting the fragment with the vector having sequences homologous to the first and second adapter sequences under conditions such that the nucleic acid fragment is incorporated into the vector by homologous recombination in vivo in a host cell. Additionally, a method for selecting for a successful transformation of a vector by a nucleic acid insert. Also, systems for cloning a nucleic acid fragment into a vector without restriction enzyme, ligase, gyrase, single stranded DNA binding protein, or other DNA modifying enzymes. Further, a kit for cloning a nucleic acid fragment into a vector.

Rapid And Enzymeless Cloning Of Nucleic Acid Fragments

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US Patent:
20030044820, Mar 6, 2003
Filed:
Apr 16, 2002
Appl. No.:
10/125789
Inventors:
Xiaowu Liang - La Jolla CA, US
Andy Teng - Fullerton CA, US
Shizhong Chen - San Diego CA, US
Dongyuan Xia - Powell OH, US
Philip Felgner - Rancho Santa Fe CA, US
International Classification:
C12Q001/68
C12P021/02
C12P019/34
C12N005/06
US Classification:
435/006000, 435/069100, 435/091200, 435/320100, 435/455000, 435/069400, 435/069500, 435/325000
Abstract:
A method for cloning a nucleic acid fragment into a vector by flanking the fragment with first and second adapter sequences, and contacting the fragment with the vector having sequences homologous to the first and second adapter sequences under conditions such that the nucleic acid fragment is incorporated into the vector by homologous recombination in vivo in a host cell. Additionally, a method for selecting for a successful transformation of a vector by a nucleic acid insert. Also, systems for cloning a nucleic acid fragment into a vector without at least one of a restriction enzyme, a ligase, a gyrase, a single stranded DNA binding protein, or other DNA modifying enzymes. Further, a kit for cloning a nucleic acid fragment into a vector.

Rapid And Enzymeless Cloning Of Nucleic Acid Fragments

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US Patent:
20050233422, Oct 20, 2005
Filed:
Jan 28, 2005
Appl. No.:
11/045686
Inventors:
Xiaowu Liang - La Jolla CA, US
Andy Teng - Fullerton CA, US
Shizhong Chen - San Diego CA, US
Dongyuan Xia - Powell OH, US
Philip Felgner - Rancho Santa Fe CA, US
International Classification:
C12P019/34
C12N015/85
US Classification:
435091200, 435455000
Abstract:
A method for cloning a nucleic acid fragment into a vector by flanking the fragment with first and second adapter sequences, and contacting the fragment with the vector having sequences homologous to the first and second adapter sequences under conditions such that the nucleic acid fragment is incorporated into the vector by homologous recombination in vivo in a host cell. Additionally, a method for selecting for a successful transformation of a vector by a nucleic acid insert. Also, systems for cloning a nucleic acid fragment into a vector without at least one of a restriction enzyme, a ligase, a gyrase, a single stranded DNA binding protein, or other DNA modifying enzymes. Further, a kit for cloning a nucleic acid fragment into a vector.

Methods Of Purifying Plasmid Dna

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US Patent:
20090227011, Sep 10, 2009
Filed:
Feb 27, 2009
Appl. No.:
12/394397
Inventors:
Shizhong Chen - San Diego CA, US
International Classification:
C12N 15/00
US Classification:
4353201
Abstract:
Described herein are novel methods to purify plasmid DNA from host cells. After a standard lysis procedure that releases plasmid DNA from the host cells, two sequential precipitation procedures separate plasmid DNA from essentially all impurities of the host cells. An optional third precipitation procedure further polishes the plasmid DNA for its most demanding applications, such as for gene therapy or pharmaceutical uses.

Toll Like Receptor 3 Antagonists, Methods And Uses

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US Patent:
20120189643, Jul 26, 2012
Filed:
Mar 5, 2012
Appl. No.:
13/412259
Inventors:
Jill M. Carton - Malvern PA, US
Shizhong Chen - San Diego CA, US
Mark Cunningham - Kennett Square PA, US
Anuk Das - Wayne PA, US
Karen Duffy - Trappe PA, US
Theresa J. Goletz - King of Prussia PA, US
David M. Knight - Berwyn PA, US
Roberta Lamb - Wynnewood PA, US
Mouhamadou L. Mbow - King of Prussia PA, US
Kristen Picha - Malvern PA, US
Gopalan Raghunathan - San Diego CA, US
Lani San Mateo - Devon PA, US
Robert T. Sarisky - Lansdale PA, US
Nicole Stowell - Havertown PA, US
Raymond Sweet - Bryn Mawr PA, US
Shanrong Zhao - San Diego CA, US
International Classification:
A61K 39/395
C12N 15/13
C12N 15/63
C12N 1/21
A61P 3/10
C12P 21/00
C12N 5/16
A61P 29/00
A61P 1/00
A61P 11/00
C07K 16/28
C12N 5/10
US Classification:
4241721, 5303891, 5303873, 5303911, 536 2353, 4353201, 4352523, 435419, 435325, 435348, 435349, 435366, 435358, 435 696, 435334, 435375
Abstract:
Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
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Shizhong Chen from San Diego, CA, age ~63 Get Report