Inventors:
Neil Desai - Santa Monica CA, US
Andrew Yang - Rosemead CA, US
Tapas De - Los Angeles CA, US
Sherry Ci - San Marino CA, US
Patrick Soon-Shiong - Los Angeles CA, US
Vuong Trieu - Calabasas CA, US
Oiang Yao - Culver City CA, US
Bridget Grim - Torrance CA, US
Assignee:
American BioScience, Inc. - Santa Monica CA
International Classification:
A61K038/13
A61K038/17
A61K031/704
A61K031/337
A61K031/56
A61K031/4745
US Classification:
514002000, 514012000, 514011000, 514291000, 514170000, 514171000, 514449000, 514034000, 514553000, 514567000, 514731000
Abstract:
The present invention relates to a pharmaceutical composition comprising a pharmaceutical agent and a pharmaceutically acceptable carrier, which carrier comprises a protein, for example, human serum albumin and/or deferoxamine. The human serum albumin is present in an amount effective to reduce one or more side effects associated with administration of the pharmaceutical composition. The invention also provides methods for reducing one or more side effects of administration of the pharmaceutical composition, methods for inhibiting microbial growth and oxidation in the pharmaceutical composition, and methods for enhancing transport and binding of a pharmaceutical agent to a cell.