Inventors:
Darryl J. Bornhop - Nashville TN, US
H. Charles Manning - Nashville TN, US
Mingfeng Bai - St. Louis MO, US
Shelby K. Wyatt - Nashville TN, US
Assignee:
Vanderbilt University - Nashville TN
International Classification:
C07D 209/56
A61K 31/47
US Classification:
514307, 514172, 51425206, 514411, 514616, 540501, 544234, 546144, 548427, 564192
Abstract:
Compounds and methods related to NIR molecular imaging, in-vitro and in-vivo functional imaging, therapy/efficacy monitoring, and cancer and metastatic activity imaging. Compounds and methods demonstrated pertain to the field of peripheral benzodiazepine receptor imaging, metabolic imaging, cellular respiration imaging, cellular proliferation imaging as targeted agents that incorporate signaling agents.