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Sharon D Real

from Kamuela, HI
Age ~61

Sharon Real Phones & Addresses

  • Kamuela, HI
  • Baltimore, MD
  • San Diego, CA
  • 5539 Ladybird Ln, La Jolla, CA 92037 (858) 456-0100 (858) 456-0175 (858) 729-0094
  • Pennington, NJ
  • Trenton, NJ
  • Los Angeles, CA
  • 5539 Ladybird Ln, La Jolla, CA 92037 (858) 456-0100

Education

Degree: Associate degree or higher

Business Records

Name / Title
Company / Classification
Phones & Addresses
Sharon Real
VP Product Development
TRACON PHARMACEUTICALS, INC
Mfg Pharmaceutical Preparations · Pharmaceutical Preparations
8910 University Ctr Ln, San Diego, CA 92122
4510 Executive Dr, San Diego, CA 92121
787 7 Ave, New York, NY 10019
(858) 550-0780

Publications

Us Patents

Process For Preparing Intermediates For Thrombin Inhibitors

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US Patent:
56103085, Mar 11, 1997
Filed:
May 18, 1995
Appl. No.:
8/443960
Inventors:
Sharon D. Real - San Diego CA
David R. Kronenthal - Yardley PA
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D21160
US Classification:
546208
Abstract:
A process is provided for preparing intermediates of the structure ##STR1## wherein Rpg is preferably. dbd. CHC. sub. 6 H. sub. 5 ; and P. G. is a protecting group CBZ or BOC, wherein a protected guanylpyrazole is reacted with an azacycloalkyl, azacycloalkenyl or azaheteroalkyl derivative (such as a piperidine derivative) in the presence of a DBU catalyst. The resulting intermediate may be used as a starting material for preparing thrombin inhibitors.

Method For Preparing A Benzaldehyde Intermediate

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US Patent:
53328400, Jul 26, 1994
Filed:
May 27, 1993
Appl. No.:
8/067885
Inventors:
Sharon D. Real - Pennington NJ
David R. Kronenthal - Yardley PA
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D49308
US Classification:
549300
Abstract:
A method is provided for preparing a chiral benzaldehyde of the structure ##STR1## by acylating an anhydride of the structure ##STR2## with a chiral oxazolidine of the structure ##STR3## where Q is MgHal or Li, and X, Y and Z are as described herein, to form a keto acid which is reduced and cyclized. The resulting benzaldehyde may be used in making the final anti-thrombotic - anti-vasospastic compounds. Novel intermediates are also provided.

Benzaldehyde Intermediates Useful In The Preparation Of 7-Oxabicycloheptane Carboxylic Acid Prostaglandin Analog Anti-Thrombotic And Anti-Vasospastic Compounds And Method For Preparing Same

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US Patent:
54363470, Jul 25, 1995
Filed:
May 20, 1994
Appl. No.:
8/247825
Inventors:
Sharon D. Real - Pennington NJ
David R. Kronenthal - Yardley PA
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D49308
US Classification:
548215
Abstract:
A method is provided for preparing a chiral benzaldehyde of the structure ##STR1## by acylating an anhydride of the structure ##STR2## with a chiral oxazolidine of the structure ##STR3## where Q is MgHal or Li, and X, Y and Z are as described herein, to form a keto acid which is reduced and cyclized. The resulting benzaldehyde may be used in making the final anti-thrombotic--anti-vasospastic compounds. Novel intermediates are also provided.

Antibody Formulations And Uses Thereof

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US Patent:
20180311359, Nov 1, 2018
Filed:
Jul 13, 2018
Appl. No.:
16/034658
Inventors:
- San Diego CA, US
Mark Cornell Manning - Johnstown CO, US
Brian M. Murphy - Fort Collins CO, US
Sharon Real - San Diego CA, US
Charles Theuer - San Diego CA, US
International Classification:
A61K 47/22
A61K 9/00
C07K 16/28
A61K 47/12
C07K 16/30
A61K 47/26
A61K 9/08
A61K 47/18
A61K 39/00
Abstract:
The present application relates to formulations of anti-CD105 antibodies, antigen-binding fragments thereof, and uses thereof. Another aspect relates to pre-filled syringes of the formulations of anti-CD105 antibodies or antigen-binding fragments thereof. Another aspect relates to the use of the formulations to reduce one or more signs or symptoms of an angiogenesis-related disorder such as cancers and ophthalmologic diseases.

Antibody Formulations And Uses Thereof

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US Patent:
20150209430, Jul 30, 2015
Filed:
Sep 5, 2013
Appl. No.:
14/421108
Inventors:
- San Diego CA, US
Mark Cornell Manning - Johnstown CO, US
Brian M. Murphy - Fort Collins CO, US
Sharon Real - San Diego CA, US
Charles Theuer - San Diego CA, US
Assignee:
Tracon Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 47/22
A61K 9/00
A61K 47/12
A61K 47/26
C07K 16/28
C07K 16/30
Abstract:
The present application relates to formulations of anti-CD105 antibodies, antigen-binding fragments thereof, and uses thereof. Another aspect relates to pre-filled syringes of the formulations of anti-CD105 antibodies or antigen-binding fragments thereof. Another aspect relates to the use of the formulations to reduce one or more signs or symptoms of an angiogenesis-related disorder such as cancers and ophthalmologic diseases.
Sharon D Real from Kamuela, HI, age ~61 Get Report