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Seungkirl Ahn Phones & Addresses

  • 100 Windhover Dr, Chapel Hill, NC 27514 (919) 967-2257
  • 322 Ivy Meadow Ln, Durham, NC 27707
  • 825 Ivy Meadow Ln, Durham, NC 27707
  • 825 Ivy Meadow Ln APT 2H, Durham, NC 27707

Work

Position: Production Occupations

Education

Degree: Graduate or professional degree

Public records

Vehicle Records

Seungkirl Ahn

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Address:
100 Windhover Dr, Chapel Hill, NC 27514
VIN:
4T1BF3EK4AU033947
Make:
TOYOTA
Model:
CAMRY
Year:
2010

Resumes

Resumes

Seungkirl Ahn Photo 1

Assistant Professor

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Location:
Chapel Hill, NC
Industry:
Hospital & Health Care
Work:
Duke University Medical Center
Assistant Professor
Education:
Duke University 1996 - 2002
Doctorates, Doctor of Philosophy, Biochemistry, Biology, Philosophy
Seoul National University 1991 - 1993
Master of Science, Masters, Molecular Biology
Skills:
Molecular Biology
Cell Biology
Biochemistry
Cell Culture
Western Blotting
Life Sciences
Cell
Drug Discovery
Languages:
Korean
Seungkirl Ahn Photo 2

Seungkirl Ahn

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Publications

Us Patents

System And Method For Homogenous Gpcr Phosphorylation And Identification Of Beta-2 Adrenergic Receptor Positive Allosteric Modulators

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US Patent:
20190241642, Aug 8, 2019
Filed:
Feb 7, 2019
Appl. No.:
16/269877
Inventors:
- Durham NC, US
Seungkirl Ahn - Durham NC, US
Biswaranjan Pani - Durham NC, US
Alem W. Kahsai - Durham NC, US
Laura Wingler - Durham NC, US
Dean Staus - Durham NC, US
International Classification:
C07K 14/705
C07K 14/47
G01N 33/68
Abstract:
The disclosure is directed to a G-protein coupled receptor complex. The complex includes (i) a chimeric G protein-coupled receptor (GPCR) comprising a non-native amino acid sequence located within the C-terminus of the GPCR and a synthetic phosphopeptide ligated to the non-native amino acid sequence; and (ii) a β-arrestin (βarr) protein bound to the C-terminus of the GPCR. The disclosure also provides an in vitro method for producing the aforementioned complex, as well as methods for identifying compounds or ligands which bind to and modulate the activity of the complex. Positive allosteric modulators of the β2 adrenergic receptor identified by screening a DNA-encoded library potentiate the activity of β2 agonists and have application in the treatment of obstructive airway disease, bronchospasm, or pre-term labor.
Seungkirl Ahn from Chapel Hill, NC, age ~57 Get Report