Inventors:
Judith Luborsky - Riverside IL, US
Seby Edassery - Skokie IL, US
Assignee:
RUSH UNIVERSITY MEDICAL CENTER - Chicago IL
International Classification:
G01N 33/566
C07K 16/40
G01N 33/577
C07K 14/47
C07K 16/18
US Classification:
435 79, 436501, 530350, 5303898, 5303882, 53038826
Abstract:
Methods and compositions, and a kit for diagnosing ovarian disorders including autoimmunity and ovarian cancer. Ovarian autoimmunity is associated with unexplained infertility or idiopathic premature ovarian failure that occurs in the absence of polyglandular disease. Methods and composition described herein are used to detect ovarian autoimmunity before the onset of ovarian dysfunction. Thus, those individuals are identified who would benefit from therapy to maintain, as well as restore, ovarian function.