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Sean H Wiedemann

from Burlington, MA
Age ~45
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Also known as:
Sean H Wiedeman
Phone and address:
11 Cutting Ln, Burlington, MA 01803
Related to:
Robert A Wiedemann, 71Carol E Wiedemann, 72
Connected to:
Carol L Wiedeman, 86Carrie A Wiedemann, 68Christopher J Wiedeman, 44Cory L Wiedeman, 32Craig D Wiedeman, 56Donna Wiedeman, 76Erin Wiedeman, 41Frank J Wiedeman, 63Gabrielle Wiedeman, 51George H Wiedeman, 81

Sean Wiedemann Phones & Addresses

  • 11 Cutting Ln, Burlington, MA 01803
  • Cambridge, MA
  • Plainsboro, NJ
  • Princeton, NJ
  • Hopewell, NJ
  • Berkeley, CA
  • Ithaca, NY

Publications

Us Patents

Processes Of Making And Crystalline Forms Of A Mdm2 Inhibitor

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US Patent:
20200281912, Sep 10, 2020
Filed:
Oct 25, 2019
Appl. No.:
16/664103
Inventors:
- Thousand Oaks CA, US
Sebastien CAILLE - Moorpark CA, US
Brian COCHRAN - Thousand Oaks CA, US
Yuanqing FANG - Belmont MA, US
Brian M. FOX - Brisbane CA, US
Brian S. LUCAS - Arlington MA, US
Lawrence R. MCGEE - Pacifica CA, US
Sean H. WIEDEMANN - Cambridge MA, US
Sarah WORTMAN - Menlo Park CA, US
Assignee:
AMGEN IINC. - Thousand Oaks CA
International Classification:
A61K 31/451
C07D 211/94
C07D 491/048
C07C 309/25
C07C 309/04
C07C 313/02
C07C 309/35
C07D 498/04
C07D 211/76
Abstract:
The present invention provides processes for making 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid as well as intermediates and processes for making the intermediates. Also provided are crystalline forms of the compound and the intermediates.

Processes Of Making And Crystalline Forms Of A Mdm2 Inhibitor

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US Patent:
20180092898, Apr 5, 2018
Filed:
Nov 22, 2017
Appl. No.:
15/820830
Inventors:
- Thousand Oaks CA, US
Sebastien CAILLE - Moorpark CA, US
Brian COCHRAN - Thousand Oaks CA, US
Yuanqing FANG - Belmont MA, US
Brian M. FOX - Brisbane CA, US
Brian S. LUCAS - Arlington MA, US
Lawrence R. MCGEE - Pacifica CA, US
Filisaty VOUNATSOS - Thousand Oaks CA, US
Sean H. WIEDEMANN - Cambridge MA, US
Sarah WORTMAN - Menlo Park CA, US
Assignee:
AMGEN INC. - Thousand Oaks CA
International Classification:
A61K 31/451
C07C 309/35
C07C 309/25
C07C 309/04
C07C 313/02
C07D 211/76
C07D 211/94
C07D 491/048
C07D 498/04
Abstract:
The present invention provides processes for making 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid as well as intermediates and processes for making the intermediates. Also provided are crystalline forms of the compound and the intermediates.

Method For The Preparation Of [1,2,4]-Triazolo[4,3-A]Pyridines

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US Patent:
20160347769, Dec 1, 2016
Filed:
Jun 24, 2014
Appl. No.:
14/900976
Inventors:
- Thousand Oaks CA, US
Eric FANG - Somerville MA, US
Jacqueline E. MILNE - Simi Valley CA, US
Sean WIEDEMANN - Cambridge MA, US
International Classification:
C07D 519/00
C07D 471/04
Abstract:
Disclosed herein are methods for preparing [1,2,4]triazolo[4,3-a]pyridines, particularly (R)-6-(1-(8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one, and precursors thereof, such as a method comprising reacting (R)—N-(3-fluoro-5-(1methyl-1H-pyrazol-4-yl) pyridin-2-yl)-2-(3-(2-methoxyethoxy)-5-oxo-1,6-naphthyridin-6(5H)yl) propanehydrazide (“HYDZ”): (HYDZ) under conditions sufficient to form (R)-6-(1-(8-fluoro-6-(1-methyl-IH-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one (“A”): (A)

Processes Of Making And Crystalline Forms Of A Mdm2 Inhibitor

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US Patent:
20160289190, Oct 6, 2016
Filed:
Jun 7, 2016
Appl. No.:
15/175824
Inventors:
- Thousand Oaks CA, US
Sebastien CAILLE - Moorpark CA, US
Brian COCHRAN - Thousand Oaks CA, US
Yuanqing FANG - Belmont MA, US
Brian M. FOX - Brisbane CA, US
Brian S. LUCAS - Arlington MA, US
Lawrence R. McGEE - Pacifica CA, US
Filisaty VOUNATSOS - Thousand Oaks CA, US
Sean H. WIEDEMANN - Cambridge MA, US
Sarah WORTMAN - Menlo Park CA, US
Assignee:
AMGEN INC. - Thousand Oaks CA
International Classification:
C07D 211/76
Abstract:
The present invention provides processes for making 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid as well as intermediates and processes for making the intermediates. Also provided are crystalline forms of the compound and the intermediates.

Processes Of Making And Crystalline Forms Of A Mdm2 Inhibitor

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US Patent:
20160289243, Oct 6, 2016
Filed:
Jun 7, 2016
Appl. No.:
15/175805
Inventors:
- Thousand Oaks CA, US
Sebastien CAILLE - Moorpark CA, US
Yuanqing FANG - Belmont MA, US
Brian M. FOX - Brisbane CA, US
Brian S. LUCAS - Arlington MA, US
Lawrence R. McGEE - Pacifica CA, US
Sean H. WIEDEMANN - Cambridge MA, US
Assignee:
AMGEN INC. - Thousand Oaks CA
International Classification:
C07D 498/04
C07C 309/35
Abstract:
The present invention provides processes for making 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid as well as intermediates and processes for making the intermediates. Also provided are crystalline forms of the compound and the intermediates.

Processes Of Making And Crystalline Forms Of A Mdm2 Inhibitor

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US Patent:
20140364455, Dec 11, 2014
Filed:
Jun 10, 2014
Appl. No.:
14/301087
Inventors:
- Thousand Oaks CA, US
Sebastien CAILLE - Moorpark CA, US
Brian COCHRAN - Thousand Oaks CA, US
Yuanqing FANG - Belmont MA, US
Brian M. FOX - Brisbane CA, US
Brian S. LUCAS - San Francisco CA, US
Lawrence R. McGEE - Pacifica CA, US
Filisaty VOUNATSOS - Thousand Oaks CA, US
Sean WIEDEMANN - Cambridge MA, US
Sarah WORTMAN - San Mateo CA, US
International Classification:
C07D 211/94
C07C 309/25
C07C 309/04
C07D 491/048
US Classification:
514327, 546221, 546115
Abstract:
The present invention provides processes for making 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid as well as intermediates and processes for making the intermediates. Also provided are crystalline forms of the compound and the intermediates.
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Sean H Wiedemann from Burlington, MA, age ~45 Get Report