Scott S Sibbett

7316320, Jan 8, 2008

Sep 18, 2003

10/666116

Scott Sibbett - Corrales NM, US
Gabriel P. Lopez - Albuquerque NM, US

Intel Corporation - Santa Clara CA
STC.UNM - Albuquerque NM

B03C 9/00
B01D 59/38

209 122, 209129, 204450

Charged particles may undergo two different separations within a single device, without manual intervention to effect the transfer of the particles between separations. In some embodiments, the device may be a Micro-Electro-Mechanical System.

7402229, Jul 22, 2008

Mar 31, 2004

10/815346

Scott Sibbett - Corrales NM, US
Dimiter Petsev - Albuquerque NM, US

Intel Corporation - Santa Clara CA
University of New Mexico - Albuquerque NM

G01N 27/453
B01L 11/00

204601, 204606, 204605, 422101

A microfluidic device and method is disclosed having one or more membranes for the control of electrolysis. In one embodiment, a microfluidic device is disclosed that includes body with first channel and second channels separated by a gel layer. A first electrode positioned in the first channel and a second electrode positioned in the second channel wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the gel layer. In another embodiment, a microfluidic device includes a body having a surface with a channel separating two first reservoirs. One or more membranes are positioned on the surface covering a portion of the channel and a blank is positioned covering the channel and the one or more membranes. A second reservoir through the blank is in contact with the membrane, each second reservoir in communication with the channel via the membrane. A first electrode is positioned in the first reservoir and a second electrode is positioned in the second reservoir wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the membranes.

7537679, May 26, 2009

Jun 14, 2004

10/868702

Scott S. Sibbett - Corrales NM, US

Intel Corporation - Santa Clara CA

G01N 27/447
G01N 27/453

204450, 204605, 204455, 204601, 204451

The present invention relates to a method of classifying charged molecules such as proteins for quantitative analysis. An analyte solution of the molecules is subjected to separational forces may be fluid drag and electrophoretic force in opposition. The analyte solution may be subjected to a two-phase process. The two-phase process may add both electrophoretic force based upon molecule charge, and differential mobility resistance based upon molecule mass and/or size.

7906026, Mar 15, 2011

Dec 1, 2008

12/315219

Scott Sibbett - Corrales NM, US

Intel Corporation - Santa Clara CA

B01D 15/34
B01D 63/08

210659, 21032184, 21050026, 21050022, 422101, 422103, 977701, 977720, 977723

Disclosed herein are an apparatus and a method for separating molecules on the basis of size and or structure, and to a method of making the apparatus. Generally, the separation method includes passing a fluid comprising particles having different effective molecular diameters through a plurality of open, nanoscale channels disposed in surfaces of substrates. The method also includes obtaining a plurality of fractions of the passed fluid such that each of the fractions includes a major portion containing particles having similar size and shape and substantially free of particles having larger size and shape. The apparatus includes first and second substrates each of which has a surface containing a plurality of open, nanoscale channels disposed therein. The surfaces are bonded together such that each of the channels of the first substrate is in fluid communication with at least two of the channels of the second substrate and is misaligned relative to the channels of the second substrate. Interferometric lithography and anodic bonding or flip-chip bonding techniques can be used to make the apparatus.

7976691, Jul 12, 2011

Feb 28, 2007

11/711819

Scott Sibbett - Corrales NM, US
Dimiter Petsev - Albuquerque NM, US

Intel Corporation - Santa Clara CA

G01N 27/453

204605, 204601

A microfluidic device and method is disclosed having one or more membranes for the control of electrolysis. In one embodiment, a microfluidic device is disclosed that includes body with first channel and second channels separated by a gel layer. A first electrode positioned in the first channel and a second electrode positioned in the second channel wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the gel layer. In another embodiment, a microfluidic device includes a body having a surface with a channel separating two first reservoirs. One or more membranes are positioned on the surface covering a portion of the channel and a blank is positioned covering the channel and the one or more membranes. A second reservoir through the blank is in contact with the membrane, each second reservoir in communication with the channel via the membrane. A first electrode is positioned in the first reservoir and a second electrode is positioned in the second reservoir wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the membranes.

8088282, Jan 3, 2012

Feb 9, 2011

13/023807

Scott Sibbett - Corrales NM, US

Intel Corporation - Santa Clara CA

B01D 15/34
B01D 15/08

210659, 210498, 21032184, 21050026, 21050022, 422502, 422503, 422504, 977701, 977720, 977723

Disclosed herein are an apparatus and a method for separating molecules on the basis of size and or structure, and to a method of making the apparatus. Generally, the separation method includes passing a fluid comprising particles having different effective molecular diameters through a plurality of open, nanoscale channels disposed in surfaces of substrates. The method also includes obtaining a plurality of fractions of the passed fluid such that each of the fractions includes a major portion containing particles having similar size and shape and substantially free of particles having larger size and shape. The apparatus includes first and second substrates each of which has a surface containing a plurality of open, nanoscale channels disposed therein. The surfaces are bonded together such that each of the channels of the first substrate is in fluid communication with at least two of the channels of the second substrate and is misaligned relative to the channels of the second substrate. Interferometric lithography and anodic bonding or flip-chip bonding techniques can be used to make the apparatus.

20030127368, Jul 10, 2003

Dec 17, 2001

10/024674

Scott Sibbett - Corrales NM, US

Intel Corporation

B03C007/00

209/129000, 209/131000

The present invention relates to a method of classifying charged molecules such as proteins for quantitative analysis. An aliquot of a body serum is subjected to separation forces may be fluid drag and electrophoretic force in opposition.

20050133437, Jun 23, 2005

Dec 17, 2003

10/738465

Scott Sibbett - Corrales NM, US

INTEL CORPORATION - Santa Clara CA

B01D063/00

210321840, 210500260, 210650000, 210500220

Disclosed herein are an apparatus and a method for separating molecules on the basis of size and or structure, and to a method of making the apparatus. Generally, the separation method includes passing a fluid comprising particles having different effective molecular diameters through a plurality of open, nanoscale channels disposed in surfaces of substrates. The method also includes obtaining a plurality of fractions of the passed fluid such that each of the fractions includes a major portion containing particles having similar size and shape and substantially free of particles having larger size and shape. The apparatus includes first and second substrates each of which has a surface containing a plurality of open, nanoscale channels disposed therein. The surfaces are bonded together such that each of the channels of the first substrate is in fluid communication with at least two of the channels of the second substrate and is misaligned relative to the channels of the second substrate. Interferometric lithography and anodic bonding or flip-chip bonding techniques can be used to make the apparatus.