Inventors:
David G. Simpson - Mechanicsville VA, US
Gary L. Bowlin - Mechanicsville VA, US
Gary E. Wnek - Midlothian VA, US
Peter J. Stevens - N. Richland Hills TX, US
Marcus E. Carr - Midlothian TX, US
Jamil A. Matthews - Glen Allen VA, US
Saravanamoorthy Rajendran - East Haven CT, US
Assignee:
Virginia Commonwealth University Intellectual Property Foundation - Richmond VA
International Classification:
C07K 1/00
C12N 5/00
C12N 5/02
A61K 38/17
A61F 2/06
US Classification:
435273, 435398, 435399, 530356, 623 147
Abstract:
The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.