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Sara Sabine Hadida Ruah

from La Jolla, CA
Age ~58

Sara Ruah Phones & Addresses

  • 2356 Torrey Pines Rd #16, La Jolla, CA 92037
  • San Diego, CA
  • Pittsburgh, PA

Publications

Us Patents

Modulators Of Atp-Binding Cassette Transporters

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US Patent:
8101767, Jan 24, 2012
Filed:
Jan 9, 2009
Appl. No.:
12/351401
Inventors:
Sara Hadida Ruah - La Jolla CA, US
Anna Hazlewood - San Diego CA, US
Peter D. J. Grootenhuis - San Diego CA, US
Fredrick Van Goor - San Diego CA, US
Ashvani Singh - San Diego CA, US
Jinglan Zhou - San Diego CA, US
Jason McCartney - Cardiff-by-the-Sea CA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
C07D 215/38
US Classification:
546159, 546153
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

Modulators Of Atp-Binding Cassette Transporters

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US Patent:
8242149, Aug 14, 2012
Filed:
Mar 13, 2006
Appl. No.:
11/374334
Inventors:
Sara Hadida Ruah - La Jolla CA, US
Anna Hazlewood - San Diego CA, US
Peter Grootenhuis - San Diego CA, US
Jinglan Zhou - San Diego CA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A01N 43/64
A01N 43/36
A01N 43/38
A61K 31/41
A61K 31/40
US Classification:
514359, 514408, 514410, 514412
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

Heteroaryl Derivatives As Cftr Modulators

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US Patent:
8299099, Oct 30, 2012
Filed:
Feb 25, 2009
Appl. No.:
12/392298
Inventors:
Sara Hadida Ruah - La Jolla CA, US
Mark Miller - San Diego CA, US
Jinglan Zhou - San Diego CA, US
Brian Bear - Oceanside CA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
C07D 213/75
A61K 31/435
US Classification:
514338, 5462841
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

Modulators Of Atp-Binding Cassette Transporters

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US Patent:
8314256, Nov 20, 2012
Filed:
Oct 6, 2006
Appl. No.:
11/544785
Inventors:
Sara Hadida Ruah - La Jolla CA, US
Anna Hazlewood - San Diego CA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
C07D 209/12
A61K 31/405
US Classification:
548493, 514419
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

Modulators Of Atp-Binding Cassette Transporters

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US Patent:
8324242, Dec 4, 2012
Filed:
Jan 9, 2009
Appl. No.:
12/351447
Inventors:
Sara Hadida Ruah - La Jolla CA, US
Anna Hazlewood - San Diego CA, US
Peter D. J. Grootenhuis - San Diego CA, US
Fredrick Van Goor - San Diego CA, US
Ashvani Singh - San Diego CA, US
Jinglan Zhou - San Diego CA, US
Jason McCartney - Cardiff-by-the-Sea CA, US
Assignee:
Vertex Pharmaceutical Incorporated - Cambridge MA
International Classification:
A61K 31/4709
A61P 3/06
A61P 43/00
A61P 3/10
A61P 35/00
A61P 25/28
A61P 25/16
US Classification:
514312
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

Pyridyl Derivatives As Cftr Modulators

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US Patent:
8524910, Sep 3, 2013
Filed:
Jun 26, 2012
Appl. No.:
13/533326
Inventors:
Sara Hadida Ruah - La Jolla CA, US
Mark Miller - San Diego CA, US
Jinglan Zhou - San Diego CA, US
Brian Bear - Oceanside CA, US
Peter Grootenhuis - San Diego CA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 31/44
C07D 405/00
US Classification:
5462837, 514338
Abstract:
The present invention relates to modulators of Formula I and the accompanying definitions herein of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases such as cystic fibrosis using such modulators.

Azaindole Derivatives As Cftr Modulators

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US Patent:
8563573, Oct 22, 2013
Filed:
Apr 13, 2009
Appl. No.:
12/422496
Inventors:
Sara Hadida Ruah - La Jolla CA, US
Jinglan Zhou - San Diego CA, US
Mark Miller - San Diego CA, US
Brian Bear - Oceanside CA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 31/44
C07D 471/02
US Classification:
514300, 546113
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

Modulators Of Atp-Binding Cassette Transporters

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US Patent:
8609703, Dec 17, 2013
Filed:
Jul 9, 2012
Appl. No.:
13/544312
Inventors:
Sara Hadida Ruah - La Jolla CA, US
Anna Hazelwood - San Diego CA, US
Peter Grootenhuis - San Diego CA, US
Jinglan Zhou - San Diego CA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A01N 43/64
A01N 43/36
A01N 43/38
A61K 31/41
A61K 31/40
US Classification:
514359, 514408, 514410, 514412
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Sara Sabine Hadida Ruah from La Jolla, CA, age ~58 Get Report