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Sai Reddy Phones & Addresses

  • Northlake, IL
  • Boulder, CO
  • Austin, TX
  • Lovell, ME

Professional Records

Medicine Doctors

Sai Reddy Photo 1

Sai S. Reddy

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Specialties:
Nephrology
Work:
Strong Renal Group
601 Elmwood Ave, Rochester, NY 14642
(585) 275-4517 (phone), (585) 442-9201 (fax)
Education:
Medical School
Temple University School of Medicine
Graduated: 1993
Procedures:
Dialysis Procedures
Conditions:
Acute Renal Failure
Anemia
Chronic Renal Disease
Hypertension (HTN)
Atherosclerosis
Languages:
English
Spanish
Description:
Dr. Reddy graduated from the Temple University School of Medicine in 1993. She works in Rochester, NY and specializes in Nephrology. Dr. Reddy is affiliated with Strong Memorial Hospital.

Publications

Us Patents

Rapid Isolation Of Monoclonal Antibodies From Animals

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US Patent:
20110312505, Dec 22, 2011
Filed:
May 17, 2011
Appl. No.:
13/109467
Inventors:
Sai Reddy - Berkeley IL, US
Xin Ge - Riverside CA, US
Jason Lavinder - Round Rock TX, US
Daniel Boutz - Austin TX, US
Andrew D. Ellington - Austin TX, US
Edward M. Marcotte - Austin TX, US
George Georgiou - Austin TX, US
International Classification:
C40B 20/00
C12Q 1/68
C07K 16/00
G01N 33/68
C12Q 1/34
G01N 33/53
US Classification:
506 2, 435 18, 435 792, 5303871, 436 89, 435 61
Abstract:
Methods and compositions for identification of candidate antigen-specific variable regions as well as generation of antibodies or antigen-binding fragments that could have desired antigen specificity are provided. For example, in certain aspects methods for determining amino acid sequences of serum antibody CDR and abundancy level are described. In some aspects, methods for determining nucleic acid sequences of antibody variable region sequences and frequency are provided. Furthermore, the invention provides methods for identification and generation of antibody or antigen-binding fragments that comprise highly-represented CDR.

Immunoglobulin Fc Polypeptides

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US Patent:
20100330076, Dec 30, 2010
Filed:
Jun 30, 2010
Appl. No.:
12/827386
Inventors:
George Georgiou - Austin TX, US
Sang Taek Jung - Austin TX, US
Sai Reddy - Austin TX, US
International Classification:
A61K 39/395
C07K 16/42
C07H 21/04
C12N 5/10
C12P 21/00
C12N 5/071
G01N 33/53
A61P 37/04
US Classification:
4241311, 5303872, 536 2353, 435325, 435 696, 435375, 435 732
Abstract:
Methods and compositions involving polypeptides having an aglycosylated antibody Fc domain. In certain embodiments, polypeptides have an aglycosylated Fc domain that contains one or more substitutions compared to a native Fc domain. Additionally, some embodiments involve an Fc domain that is binds some Fc receptors but not others. For example, polypeptides are provided with an aglycosylated Fe domain that selectively binds FcγRI at a level within 2-fold of a glycosylated Fc domain, but that is significantly reduced for binding to other Fc receptors. Furthermore, methods and compositions are provided for promoting antibody-dependent cell-mediated toxicity (ADCC) using a polypeptide having a modified aglycosylated Fc domain and a second non-Fc binding domain, which can be an antigen binding region of an antibody or a non-antigen binding region. Some embodiments concern antibodies with such polypeptides, which may have the same or different non-Fc binding domain.

Service Retry Collision Prevention Using Prime Numbers

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US Patent:
20210157688, May 27, 2021
Filed:
Nov 26, 2019
Appl. No.:
16/695243
Inventors:
- Armonk NY, US
Xinyun Zhao - Cedar Park TX, US
Sihang Bob Fang - Culver City CA, US
Manali Jairam Chanchlani - Redmond WA, US
Rahul P. Akolkar - Lexington KY, US
Sai Karthik Reddy Ginni - New York NY, US
Kristi Farinelli - Albrightsville PA, US
International Classification:
G06F 11/14
H04L 12/24
Abstract:
Technology for determining an amount of time to wait to retry requests to a representational state transfer (REST) server system for a REST resource, where the time to wait is always chosen to be a prime number of time units (for example, slots, milliseconds). While currently conventional systems will sometimes use a prime number of time units to wait for a retry request, various embodiments of the present invention will always, and invariably, use a prime number of time units. The REST resource may be, for example, a REST application programming interface (API) that is requested by and delivered to a client system using hypertext transfer protocol (HTTP).

Immunoglobulin Fc Polypeptides

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US Patent:
20140235482, Aug 21, 2014
Filed:
Feb 14, 2014
Appl. No.:
14/181594
Inventors:
- Carson City NV, US
Sang Taek JUNG - Seoul, KR
Sai REDDY - Austin TX, US
Assignee:
RESEARCH DEVELOPMENT FOUNDATION - Carson City NV
International Classification:
G01N 33/569
US Classification:
506 9
Abstract:
Methods and compositions involving polypeptides having an aglycosylated antibody Fc domain. In certain embodiments, polypeptides have an aglycosylated Fc domain that contains one or more substitutions compared to a native Fc domain. Additionally, some embodiments involve an Fc domain that is binds some Fc receptors but not others. For example, polypeptides are provided with an aglycosylated Fc domain that selectively binds FcγRI at a level within 2-fold of a glycosylated Fc domain, but that is significantly reduced for binding to other Fc receptors. Furthermore, methods and compositions are provided for promoting antibody-dependent cell-mediated toxicity (ADCC) using a polypeptide having a modified aglycosylated Fc domain and a second non-Fc binding domain, which can be an antigen binding region of an antibody or a non-antigen binding region. Some embodiments concern antibodies with such polypeptides, which may have the same or different non-Fc binding domain.
Sai T Reddy from Northlake, IL, age ~44 Get Report