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Russell G Dushin

from Old Lyme, CT
Age ~65

Russell Dushin Phones & Addresses

  • 15 Jericho Dr, Old Lyme, CT 06371 (845) 300-2863
  • 2 Johnny Cake Hill Rd, Old Lyme, CT 06371 (860) 598-9363
  • 188 Mountain Pass, Garrison, NY 10524 (845) 788-0020
  • 667 Route 9D, Garrison, NY 10524
  • Philipstown, NY
  • Mohegan Lake, NY
  • Peekskill, NY
  • 15 Jericho Dr, Old Lyme, CT 06371

Work

Company: Pfizer Jan 2010 to May 2018 Position: Associate research fellow

Education

School / High School: Yale University 1989 to 1991 Specialities: Chemistry

Skills

Drug Discovery • Medicinal Chemistry • Drug Development • Drug Design • Organic Synthesis • Organic Chemistry • Hplc • Lc Ms • Pharmaceutical Industry • Lead Change • Chromatography • Biotechnology • Technology Transfer • Oncology • Adme • Parallel Synthesis • Chemistry • Pharmacology

Industries

Pharmaceuticals

Resumes

Resumes

Russell Dushin Photo 1

Founding Manager

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Location:
15 Jericho Dr, Old Lyme, CT 06371
Industry:
Pharmaceuticals
Work:
Pfizer Jan 2010 - May 2018
Associate Research Fellow

Rgd Solutions Jan 2010 - May 2018
Founding Manager

Pfizer 1995 - Jan 2010
Senior Scientist I Through Principal Research Scientist Iii

American Cyanamid 1991 - 1994
Senior Research Chemist and Senior Research Chemist I
Education:
Yale University 1989 - 1991
Cornell University 1984 - 1989
Master of Science, Doctorates, Masters, Doctor of Philosophy, Biochemistry, Organic Chemistry
University of Iowa 1983 - 1984
Master of Science, Masters, Chemistry
State University of New York College of Environmental Sciences and Forestry 1978 - 1982
Bachelors, Bachelor of Science, Chemistry
Skills:
Drug Discovery
Medicinal Chemistry
Drug Development
Drug Design
Organic Synthesis
Organic Chemistry
Hplc
Lc Ms
Pharmaceutical Industry
Lead Change
Chromatography
Biotechnology
Technology Transfer
Oncology
Adme
Parallel Synthesis
Chemistry
Pharmacology

Publications

Us Patents

Acetamide And Substituted Acetamide-Containing Thiourea Inhibitors Of Herpes Viruses

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US Patent:
6335350, Jan 1, 2002
Filed:
Nov 22, 1999
Appl. No.:
09/447005
Inventors:
Jonathan Bloom - Nyack NY
Martin DiGrandi - Piermont NY
Russell Dushin - Garrison NY
Stanley Lang - Carlsbad CA
Bryan OHara - Norwood NJ
Assignee:
American Home Products Corporation - Madison NJ
International Classification:
C07D21126
US Classification:
514331, 514378, 514408, 514587, 546229, 548247, 548568, 564 17
Abstract:
Compounds of the formula: are useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and -7, and Kaposi herpesvirus.

Aminopyridine-Containing Thiourea Inhibitors Of Herpes Viruses

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US Patent:
6380243, Apr 30, 2002
Filed:
Mar 12, 2001
Appl. No.:
09/804510
Inventors:
Jonathan Bloom - Nyack NY
Martin DiGrandi - Piermont NY
Russell Dushin - Garrison NY
Stanley Lang - Carlsbad CA
Bryan OHara - Norwood NJ
Assignee:
American Home Products Corporation - Madison NJ
International Classification:
C07D30702
US Classification:
514438, 514461, 514361, 549 77, 549493, 548125
Abstract:
Compounds of the formula wherein A is heteroaryl; R -R are independently hydrogen, alkyl of 1 to 4 carbon atoms, perhaloalkyl of 1 to 4 carbon atoms, halogen, alkoxy of 1 to 4 carbon atoms, or cyano, or R and R or R and R may be taken together to form aryl of 5 to 7 carbon atoms; W is O, NR , or is absent; G is aryl or heteroaryl; and X is a bond X is a bond, âNH, alkyl of 1 to 6 carbon atoms, alkenyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, thioalkyl of 1 to 6 carbon atoms, alkylamino of 1 to 6 carbon atoms, or (CH)J; and J is alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, phenyl or benzyl; and n is an integer from 1 to 6; or a pharmaceutical salt thereof, useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and -7, and Kaposi herpesvirus.

Diaminopyridine-Containing Thiourea Inhibitors Of Herpes Viruses

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US Patent:
6403617, Jun 11, 2002
Filed:
Sep 26, 2000
Appl. No.:
09/669535
Inventors:
Jonathan Bloom - Nyack NY
Martin DiGrandi - Piermont NY
Russell Dushin - Garrison NY
Stanley Lang - Carlsbad CA
Bryan OHara - Norwood NJ
Assignee:
American Home Products Corp. - Madison NJ
International Classification:
A61K 3144
US Classification:
514352, 514353, 546305, 546306, 546307
Abstract:
Compounds of the formula Useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, humanherpesviruses-6 and -7, and Kaposi herpesvirus.

Diaminopyridine-Containing Thiourea Inhibitors Of Herpes Viruses

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US Patent:
6407123, Jun 18, 2002
Filed:
Sep 26, 2000
Appl. No.:
09/670180
Inventors:
Jonathan Bloom - Nyack NY
Martin DiGrandi - Piermont NY
Russell Dushin - Garrison NY
Stanley Lang - Carlsbad CA
Bryan OHara - Norwood NJ
Assignee:
American Home Products Corporation - Madison NJ
International Classification:
A61K 31443
US Classification:
514336, 514340, 5462687, 5462797, 546208, 546212
Abstract:
Compounds of the formula wherein R -R are independently selected from hydrogen, alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms, alkynyl of 2 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, heterocycloalkyl of 3 to 10 carbon members, aryl, heteroaryl, halogen, âCN, âNO , âCO R , âCOR , âOR , âSR , âSOR , âSO R , âCONR R , âNR N(R R ), âN(R R ) or WâYâ(CH ) âZ ; or R and R or R and R , taken together form a 3 to 7 membered heterocycloalkyl or 3 to 7 membered heteroaryl; R and R are independently hydrogen, alkyl of 1 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, or aryl; R is hydrogen, alkyl of 1 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, heterocycloalkyl of 3 to 10 members, aryl or heteroaryl, or R and R , taken together may form a 3 to 7 membered heterocycloalkyl; A is heteroaryl.

Heterocyclic Carboxamide-Containing Thiourea Inhibitors Of Herpes Viruses Containing A Substituted Phenylenediamine Group

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US Patent:
6407249, Jun 18, 2002
Filed:
Dec 29, 2000
Appl. No.:
09/684011
Inventors:
Jonathan Bloom - Nyack NY
Kevin Curran - Nyack NY
Martin DiGrandi - Congers NY
Russell Dushin - Garrison NY
Thomas Jones - New City NY
Stanley Lang - Blauvent NY
Adma Ross - Suffern NY
Eugene A. Terefenko - Quakertown PA
Bryan OHara - Norwood NJ
Assignee:
American Home Products Corporation - Madison NJ
International Classification:
A61K 31341
US Classification:
546461, 549483, 549487
Abstract:
Compounds of the formula: wherein R -R are independently selected from hydrogen, alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms, alkynyl of 2 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, heterocycloalkyl of 3 to 10 carbon members, aryl, heteroaryl, halogen, âCN, âNO , âCO R , âCOR , âOR , âSR , âSOR , âSO R , âCONR R , âNR N(R R ), âN(R R ) or WâYâ(CH ) âZ provided that at least one of R -R is not hydrogen; or R and R or R and R , taken together form a 3 to 7 membered heterocycloalkyl or 3 to 7 membered heteroaryl; R and R are independently hydrogen, alkyl of 1 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, or aryl; R is hydrogen, alkyl of 1 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, heterocycloalkyl of 3 to 10 members, aryl or heteroaryl, or R and R , taken together may form a 3 to 7 membered heterocycloalkyl; R -R are independently hydrogen, alkyl of 1 to 4 carbon atoms, perhaloalkyl of 1 to 4 carbon atoms, halogen, alkoxy of 1 to 4 carbon atoms, or cyano, or R and R or R and R may be taken together to form aryl of 5 to 7 carbon atoms; provided that at least one of R is not hydrogen; W is O, NR , or is absent; Y is â(CO)â or â(CO )â, or is absent; Z is alkyl of 1 to 4 carbon atoms, âCN, âCO R , COR , âCONR R , âOCOR , âNR COR , âOCONR , âOR , âSR , âSOR , âSO R , SR6N(R7R8), âN(R R R) or phenyl; G is a monocyclic heteroaryl; X is a bond, âNH, alkyl of 1 to 6 carbon atoms, alkenyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, or thioalkyl of 1 to 6 carbon atoms, alkylamino of 1 to 6 carbon atoms, or (CH)J; J is alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, phenyl or benzyl; and n is an integer from 1 to 6 useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and -7, and Kaposi herpesvirus.

Heterocyclic Carboxamide-Containing Thiourea Inhibitors Of Herpes Viruses Containing A Substituted Phenylenediamine Group

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US Patent:
6410571, Jun 25, 2002
Filed:
Dec 29, 2000
Appl. No.:
09/684773
Inventors:
Jonathan Bloom - Nyack NY
Kevin Curran - Nyack NY
Martin DiGrandi - Congers NY
Russell Dushin - Garrison NY
Thomas Jones - New City NY
Stanley Lang - Blauvent NY
Adma Ross - Suffern NY
Eugene A. Terefenko - Quakertown PA
Bryan OHara - Norwood NJ
Assignee:
American Home Products Corporation - Madison NJ
International Classification:
A61K 3144
US Classification:
514354, 514357, 546314, 546323, 546331
Abstract:
Compounds of the formula: wherein the substituents are defined herein which are useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and -7, and Kaposi herpesvirus.

Heterocyclic Carboxamide-Containing Thiourea Inhibitors Of Herpes Viruses Containing Phenylenediamine Group

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US Patent:
6426355, Jul 30, 2002
Filed:
Sep 27, 2000
Appl. No.:
09/671486
Inventors:
Jonathan Bloom - Nyack NY
Kevin Curran - Nyack NY
Martin DiGrandi - Piermont NY
Russell Dushin - Garrison NY
Thomas Jones - New City NY
Stanley Lang - Carlsbad CA
Adma Ross - Suffern NY
Eugene A. Terefenko - Quakertown PA
Bryan OHara - Norwood NJ
Assignee:
American Home Products - Madison NJ
International Classification:
A61K 31433
US Classification:
514361, 548127, 548235, 5483335, 5483741, 548561, 549 72, 549487, 514374, 514400, 514406, 514423, 514448, 514461, 435 5
Abstract:
Compounds having the formula: wherein R -R , X and G are described herein and which are useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and -7, and Kaposi herpesvirus.

Alpha-Methylbenzyl-Containing Thiourea Inhibitors Of Herpes Viruses Containing A Phenylenediamine Group

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US Patent:
6462055, Oct 8, 2002
Filed:
Apr 30, 2001
Appl. No.:
09/845428
Inventors:
Jonathan Bloom - Nyack NY
Kevin Curran - Nyack NY
Martin DiGrandi - Piermont NY
Russell Dushin - Garrison NY
Stanley Lang - Carlsbad CA
Emily Norton - Nyack NY
Adma Ross - Rockland NY
Bryan OHara - Norwood NJ
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 3147
US Classification:
514307, 514309, 514310, 514311, 514312, 514313, 514469, 514470, 546141, 546143, 546156, 546162, 549466, 549467, 549468
Abstract:
Compounds having the formula: wherein R -R are independently selected from hydrogen, alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms, alkynyl of 2 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, heterocycloalkyl of 3 to 10 carbon members, aryl, heteroaryl, halogen, âCN, âNO , âCO R , âCOR , âOR , âSR , âSOR , âSO R , âCONR R , âNR N(R R ), âN(R R ) or W-Y-(CH ) -Z provided that at least one of R -R is not hydrogen; or R and R or R and R , taken together form a 3 to 7 membered heterocycloalkyl or 3 to 7 membered heteroaryl; R and R are independently hydrogen, alkyl of 1 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, or aryl; R is hydrogen, alkyl of 1 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, heterocycloalkyl of 3 to 10 members, aryl or heteroaryl, or R and R , taken together may form a 3 to 7 membered heterocycloalkyl; W is O, NR , or is absent; Y is â(CO)â or â(CO )â, or is absent; Z is alkyl of 1 to 4 carbon atoms, âCN, âCO R , COR , âCONR R , âOCOR , âNR COR , âOCONR , âOR , âSR , âSOR , âSO R , SR6N(R7R8), âN(R R ) or phenyl; G is aryl or fused bicyclic heteroaryl; X is a bond, âNH, alkyl of 1 to 6 carbon atoms, alkenyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, thioalkyl of 1 to 6 carbon atoms, alkylamino of 1 to 6 carbon atoms, or (CH)J; J is alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, phenyl or benzyl; and n is an integer from 1 to 6; useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and -7, and Kaposi herpesvirus.
Russell G Dushin from Old Lyme, CT, age ~65 Get Report