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Rudrajit Mal

from Hillsborough, NJ
Age ~42
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Also known as:
Mal Rudrajit
Connected to:
Marc J Mal, 48Michael A Mal, 36Ravi Mal, 81Tony Mal, 66Elizabeth R Mala, 57Eva Mala, 46Phyllis Malaba, 32Marion T Malabad, 86Andrey J Malabanan, 41Arnel O Malabanan, 57

Rudrajit Mal Phones & Addresses

  • Hillsborough, NJ
  • Edison, NJ
  • Piscataway, NJ

Work

Company: Merck Oct 2009 Position: Chemist

Education

Degree: Masters School / High School: Rutgers University Jan 1, 2006 to 2009 Specialities: Chemistry

Skills

Uv/Vis • Hplc • Organic Synthesis • Nmr • Chemistry • Drug Discovery • Organic Chemistry • Protein Chemistry • Drug Delivery • Purification • Mass Spectrometry • Analytical Chemistry • Lc Ms • Spectroscopy • Assay Development • Ir • Chromatography

Ranks

Certificate: Certified Associate In Project Management (Capm)

Industries

Pharmaceuticals

Resumes

Resumes

Rudrajit Mal Photo 1

Chemist

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Location:
Kenilworth, NJ
Industry:
Pharmaceuticals
Work:
Merck
Chemist
Education:
Rutgers University Jan 1, 2006 - 2009
Masters, Chemistry Indian Institute of Technology, Guwahati Jan 1, 2004 - 2006
Master of Science, Masters, Chemistry
Skills:
Uv/Vis
Hplc
Organic Synthesis
Nmr
Chemistry
Drug Discovery
Organic Chemistry
Protein Chemistry
Drug Delivery
Purification
Mass Spectrometry
Analytical Chemistry
Lc Ms
Spectroscopy
Assay Development
Ir
Chromatography
Certifications:
Certified Associate In Project Management (Capm)

Publications

Us Patents

Mineralocorticoid Receptor Antagonists

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US Patent:
20130331419, Dec 12, 2013
Filed:
Jan 19, 2012
Appl. No.:
13/979875
Inventors:
Alejandro Crespo - Edison NJ, US
Ping Lan - Dayton NJ, US
Rudrajit Mal - Edison NJ, US
Anthony Ogawa - Mountainside NJ, US
Hong Shen - West Windsor NJ, US
Peter J. Sinclair - Scotch Plains NJ, US
Zhongxiang Sun - Edison NJ, US
Ellen K. Vande Bunte - Colts Neck NJ, US
Zhicai Wu - Montvale NJ, US
Kun Liu - Shanghai, CN
Robert J. DeVita - Westfield NJ, US
Min Shu - Greenbrook NJ, US
John Qiang Tan - Westfield NJ, US
Changhe Qi - Shanghai, CN
Yuguang Wang - Shanghai, CN
Richard Beresis - Shanghai, CN
International Classification:
C07D 209/08
A61K 45/06
C07D 231/56
A61K 31/416
A61K 31/422
C07D 413/06
A61K 31/4245
C07D 403/06
A61K 31/4196
A61K 31/405
A61K 31/404
US Classification:
514364, 548510, 514415, 5483625, 514406, 548509, 548131, 5482664, 514383, 548143, 548235, 514374, 548252, 514381
Abstract:
Disclosed are the compounds of the Formula (I) as well as pharmaceutically acceptable salts thereof, which are useful for treating aldosterone-mediated diseases. The processes for preparing compounds of the Formula (I), the use for the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and the pharmaceutical compositions which comprise compounds of the formula (I) are disclosed too.

Biaryl Monobactam Compounds And Methods Of Use Thereof For The Treatment Of Bacterial Infections

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US Patent:
20200361928, Nov 19, 2020
Filed:
Jun 25, 2020
Appl. No.:
16/912146
Inventors:
- Rahway NJ, US
Weiguo Liu - Princeton Junction NJ, US
Wanying Sun - Edison NJ, US
Yi Zang - Princeton NJ, US
Weidong Pan - Hillsborough NJ, US
Anthony Ogawa - Mateo CA, US
Linda Brockunier - Orange NJ, US
Xianhai Huang - Warren NJ, US
Hongwu Wang - Westfield NJ, US
Rudrajit Mal - Edison NJ, US
Tesfaye Biftu - Freehold NJ, US
Min Park - Morristown NJ, US
Yan Guo - Westfield NJ, US
Jinlong Jiang - Scotch Plains NJ, US
Helen Y. Chen - Marlboro NJ, US
Christopher W. Plummer - Cranford NJ, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
C07D 417/14
C07D 471/04
C07C 53/18
C07F 9/6558
A61K 31/433
A61K 31/444
A61K 31/4439
A61K 45/06
A61P 31/04
A61K 31/427
Abstract:
The present invention relates to biaryl monobactam compounds of Formula Iand pharmaceutically acceptable salts thereof, wherein X, Y, Z, A, Q, A, M, W, Rand Rare as defined herein. The present invention also relates to compositions which comprise a biaryl monobactam compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. The invention further relates to methods for treating a bacterial infection comprising administering to the patient a therapeutically effective amount of a compound of the invention, either alone or in combination with a therapeutically effective amount of a second beta-lactam antibiotic.

Biaryl Monobactam Compounds And Methods Of Use Thereof For The Treatment Of Bacterial Infections

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US Patent:
20180339983, Nov 29, 2018
Filed:
Dec 12, 2016
Appl. No.:
15/775487
Inventors:
- Rahway NJ, US
Weiguo Liu - Princeton NJ, US
Wanying Sun - Edison NJ, US
Yi Zang - Princeton NJ, US
Weidong Pan - Hillsborough NJ, US
Anthony Ogawa - South San Francisco CA, US
Linda Brockunier - Orange NJ, US
Xianhai Huang - Warren NJ, US
Hongwu Wang - Westfield NJ, US
Rudrajit Mal - Piscataway NJ, US
Tesfaye Biftu - Freehold NJ, US
Min Park - Whippany NJ, US
Yan Guo - Westfield NJ, US
Jinlong Jiang - Scotch Plains NJ, US
Helen Y. Chen - Marlboro NJ, US
Christopher W. Plummer - Hoboken NJ, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
C07D 417/14
A61K 31/427
A61P 31/04
Abstract:
The present invention relates to biaryl monobactam compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein X, Y, Z, A, Q, M, W, Rand Rare as defined herein. The present invention also relates to compositions which comprise a biaryl monobactam compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. The invention further relates to methods for treating a bacterial infection comprising administering to the patient a therapeutically effective amount of a compound of the invention, either alone or in combination with a therapeutically effective amount of a second beta-lactam antibiotic.

Factor Xia Inhibitors

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US Patent:
20180079743, Mar 22, 2018
Filed:
Apr 11, 2016
Appl. No.:
15/565748
Inventors:
- Rahway NJ, US
Scott D. Edmondson - Concord MA, US
Wanying Sun - Edison NJ, US
Weiguo Liu - Princeton NJ, US
Santhosh F. Neelamkavil - Edison NJ, US
Alan Hruza - Hackettstown NJ, US
Yi Zang - Princeton Junction NJ, US
Amjad Ali - Freehold NJ, US
Rudrajit Mal - Piscataway NJ, US
Jiafang He - South Brunswick NJ, US
Rongze Kuang - Green Brook NJ, US
Heping Wu - Edison NJ, US
Anthony K. Ogawa - New Providence NJ, US
Andrew F. Nolting - Trenton NJ, US
Assignee:
MERCK SHARP & DOHME CORP. - Rahway NJ
International Classification:
C07D 401/14
C07D 409/14
C07D 413/14
Abstract:
The present invention provides a compound of Formula (I); and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein.

Factor Xia Inhibitors

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US Patent:
20160347757, Dec 1, 2016
Filed:
Feb 6, 2015
Appl. No.:
15/116659
Inventors:
Santhosh F. NEELAMKAVIL - Kenilworth NJ, US
Scott D. EDMONDSON - Kenilworth NJ, US
Zhuyan GUO - Kenilworth NJ, US
Alan W. HRUZA - Kenilworth NJ, US
Zahid HUSSAIN - Kenilworth NJ, US
Charles A. LESBURG - Boston MA, US
Remond MONINGKA - Kenilworth NJ, US
Anthony K. OGAWA - Kenilworth NJ, US
Rudrajit MAL - Kenilworth NJ, US
- Rahway NJ, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
C07D 487/08
C07D 471/08
Abstract:
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein.

Mineralocorticoid Receptor Antagonists

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US Patent:
20150284376, Oct 8, 2015
Filed:
Dec 2, 2014
Appl. No.:
14/557980
Inventors:
- Rahway NJ, US
Ping Lan - Dayton NJ, US
Rudrajit Mal - Edison NJ, US
Anthony Ogawa - Mountainside NJ, US
Hong Shen - Shanghai, CN
Peter J. Sinclair - Doylestown PA, US
Zhongxiang Sun - Edison NJ, US
Ellen K. Vande Bunte - Hawthorne NJ, US
Zhicai Wu - Montvale NJ, US
Kun Liu - Boston MA, US
Robert J. DeVita - Westfield NJ, US
Min Shu - Greenbrook NJ, US
John Qiang Tan - Westfield NJ, US
Changhe Qi - Shanghai, CN
Yuguang Wang - Shanghai, CN
Richard Beresis - Shanghai, CN
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
C07D 413/06
A61K 31/405
C07D 231/56
A61K 31/416
A61K 31/4045
A61K 45/06
C07D 403/06
A61K 31/4196
A61K 31/422
C07D 403/04
A61K 31/404
C07D 405/06
C07D 209/08
A61K 31/4245
Abstract:
The present invention is directed to compounds of the Formula Ias well as pharmaceutically acceptable salts thereof, that are useful for treating aldosterone-mediated diseases. The invention furthermore relates to processes for preparing compounds of the Formula I, to their use for the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical compositions which comprise compounds of the Formula I.
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Rudrajit Mal from Hillsborough, NJ, age ~42 Get Report