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Rolf E Kuestner

from Bothell, WA
Age ~66
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Also known as:
Rolf F Kuestner, Susan Kuestner, Vestner K Rolf
Phone and address:
24208 23Rd Ave, Bothell, WA 98021
(425) 486-8599
Related to:
John Phillip Hilbert, 47Susan E Kuestner, 65Alexander Kuestner, 37Bryan D Gaston, 37Holly Kuestner, 35Phyllis L Kuestner, 94Paul G Kuestner
Connected to:
Christopher Kuestner, 39Frank Kuestner, 51Trever D Kuetemeyer, 34Vincent F Kuetemeyer, 83Brad R Kueter, 41Hubert C Kueter, 94Jenelle N Kueter, 51John R Kueter, 77Maricarrol A Kueter, 68Troy A Kueter, 55

Rolf Kuestner Phones & Addresses

  • 24208 23Rd Ave, Bothell, WA 98021 (425) 486-8599 (425) 381-0601
  • Lynnwood, WA
  • Methuen, MA

Work

Company: Lumen bioscience Apr 2017 Position: Senior associate scientist

Education

School / High School: University of Arizona 1984 to 1986 Specialities: Molecular Biology

Skills

Molecular Biology • Biotechnology • Cell Culture • Life Sciences • Drug Discovery • Biochemistry • Lifesciences • Protein Chemistry • Cell Biology • Elisa • Protein Expression • Assay Development • Immunology • Tissue Culture

Industries

Biotechnology

Public records

Vehicle Records

Rolf Kuestner

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Address:
24208 23 Ave W, Bothell, WA 98021
Phone:
(425) 486-8599
VIN:
JTDKB20U177547068
Make:
TOYOTA
Model:
PRIUS
Year:
2007

Resumes

Resumes

Rolf Kuestner Photo 1

Senior Associate Scientist

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Location:
Bothell, WA
Industry:
Biotechnology
Work:
Lumen Bioscience
Senior Associate Scientist
Matrix Genetics Jul 2013 - Mar 2017
Senior Associate Scientist
Institute For Systems Biology Apr 2008 - 2013
Research Associate 4
Zymogenetics Feb 1991 - Mar 2008
Scientist
T Cell Sciences 1987 - 1991
Scientist
Education:
University of Arizona 1984 - 1986
Ohio University Heritage College of Osteopathic Medicine
Montana State University - Bozeman
Master of Science, Masters, Agronomy, Molecular Biology
Skills:
Molecular Biology
Biotechnology
Cell Culture
Life Sciences
Drug Discovery
Biochemistry
Lifesciences
Protein Chemistry
Cell Biology
Elisa
Protein Expression
Assay Development
Immunology
Tissue Culture

Publications

Us Patents

Murine Zcytor17 Ligand Polypeptides

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US Patent:
7507795, Mar 24, 2009
Filed:
Dec 13, 2006
Appl. No.:
11/610126
Inventors:
Cindy A. Sprecher - Hereford AZ, US
Joseph L. Kuijper - Kenmore WA, US
Maria M. Dasovich - Seattle WA, US
Francis J. Grant - Seattle WA, US
Jane A. Gross - Seattle WA, US
Angela K. Hammond - Kirkland WA, US
Rolf E. Kuestner - Bothell WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C07K 14/52
C12N 15/63
US Classification:
530351, 435 695
Abstract:
The present invention relates to zcytor17lig polynucleotide, polypeptide and anti-zcytor17 antibody molecules. The zcytor17lig is a novel cytokine. The polypeptides may be used within methods for stimulating the immune system, and proliferation and/or development of hematopoietic cells in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

Antibodies To Murine Zcytor17 Ligand

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US Patent:
7531636, May 12, 2009
Filed:
Dec 19, 2006
Appl. No.:
11/613091
Inventors:
Cindy A. Sprecher - Hereford AZ, US
Joseph L. Kuijper - Kenmore WA, US
Maria M. Dasovich - Seattle WA, US
Francis J. Grant - Seattle WA, US
Angela K. Hammond - Kirkland WA, US
Jane A. Gross - Seattle WA, US
Rolf E. Kuestner - Bothell WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C07K 16/24
US Classification:
5303879, 5303873, 5303881
Abstract:
The present invention relates to zcytor17lig polynucleotide, polypeptide and anti-zcytor17 antibody molecules. The zcytor17lig is a novel cytokine. The polypeptides may be used within methods for stimulating the immune system, and proliferation and/or development of hematopoietic cells in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

Method Of Treating Inflammation Using Soluble Il-17Rcx4

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US Patent:
7622116, Nov 24, 2009
Filed:
Feb 9, 2007
Appl. No.:
11/673094
Inventors:
Rolf E. Kuestner - Bothell WA, US
Zeren Gao - Redmond WA, US
Steven D. Levin - Seattle WA, US
Mark W. Rixon - Issaquah WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 39/395
A61K 38/00
C07K 14/00
C07K 17/00
C12P 21/08
C07K 16/00
C07K 17/14
US Classification:
4241441, 514 12, 530350, 530388322, 5303911
Abstract:
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17F, IL-17A, or both IL-17A and IL-17F polypeptide molecules. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. IL-17RC is a common receptor for IL-17A and IL-17F. The present invention includes methods of using a soluble IL-17RC receptor, IL-17RCx4 for treating inflammation.

Murine Zcytor17 Ligand Polypeptides

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US Patent:
7740834, Jun 22, 2010
Filed:
Jan 29, 2009
Appl. No.:
12/362318
Inventors:
Cindy A. Sprecher - Hereford AZ, US
Joseph L. Kuijper - Kenmore WA, US
Maria M. Dasovich - Seattle WA, US
Francis J. Grant - Seattle WA, US
Jane A. Gross - Seattle WA, US
Angela K. Hammond - Kirkland WA, US
Rolf E Kuestner - Bothell WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C07K 14/52
C12N 15/63
C12N 5/10
A61K 38/19
US Classification:
424 851, 435 695, 4352523, 4353201, 435325, 530351
Abstract:
The present invention relates to zcytor17lig polynucleotide, polypeptide and anti-zcytor17 antibody molecules. The zcytor17lig is a novel cytokine. The polypeptides may be used within methods for stimulating the immune system, and proliferation and/or development of hematopoietic cells in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

Soluble Zcytor14, Anti-Zcytor14 Antibodies And Binding Partners And Methods Of Using In Inflammation

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US Patent:
7910540, Mar 22, 2011
Filed:
Jun 10, 2005
Appl. No.:
11/150533
Inventors:
Steven D. Levin - Seattle WA, US
Rolf E. Kuestner - Bothell WA, US
Zeren Gao - Redmond WA, US
Stephen R. Jaspers - Edmonds WA, US
Janine Bilsborough - Seattle WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 38/00
US Classification:
514 11, 4241301, 4241341, 530350, 530351
Abstract:
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17F, IL-17A, or both IL-17A and IL-17F polypeptide molecules. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. ZcytoR14 is a common receptor for IL-17A and IL-17F. The present invention includes soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners, as well as methods for antagonizing IL-17F, IL-17A or both IL-17A and IL-17F using such soluble receptors, antibodies and binding partners.

Soluble Il-17Rcx4 And Fusion Proteins Thereof

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US Patent:
8093355, Jan 10, 2012
Filed:
Oct 15, 2009
Appl. No.:
12/580112
Inventors:
Rolf E. Kuestner - Bothell WA, US
Zeren Gao - Shanghai, CN
Steven D. Levin - Seattle WA, US
Mark W. Rixon - Issaquah WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C07K 1/00
C07K 14/00
C07K 17/00
US Classification:
530350
Abstract:
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17F, IL-17A, or both IL-17A and IL-17F polypeptide molecules. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. IL-17RC is a common receptor for IL-17A and IL-17F. The present invention includes methods of using a soluble IL-17RC receptor, IL-17RCx4 for treating inflammation.

Murine Zcytor17 Ligand Polynucleotides

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US Patent:
8124378, Feb 28, 2012
Filed:
Apr 8, 2010
Appl. No.:
12/756959
Inventors:
Cindy A. Sprecher - Hereford AZ, US
Joseph L. Kuijper - Kenmore WA, US
Maria M. Dasovich - Seattle WA, US
Francis J. Grant - Seattle WA, US
Jane A. Gross - Seattle WA, US
Angela K. Hammond - Kirkland WA, US
Rolf E. Kuestner - Bothell WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C12N 5/10
C12N 15/19
C12N 15/63
C12N 15/64
US Classification:
435 695, 4352523, 4353201, 435325, 536 235
Abstract:
The present invention relates to zcytor17lig polynucleotide, polypeptide and anti-zcytor17 antibody molecules. The zcytor17lig is a novel cytokine. The polypeptides may be used within methods for stimulating the immune system, and proliferation and/or development of hematopoietic cells in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

Methods Of Treating Multiple Sclerosis (Ms) Using An Il-17A And Il-17F Antagonist

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US Patent:
8268773, Sep 18, 2012
Filed:
Jan 27, 2011
Appl. No.:
13/015304
Inventors:
Scott R. Presnell - Tacoma WA, US
Steven K. Burkhead - Hershey PA, US
Steven D. Levin - Seattle WA, US
Rolf E. Kuestner - Bothell WA, US
Zeren Gao - Redmond WA, US
Stephen R. Jaspers - Brewster NY, US
Janine Bilsborough - Seattle WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 38/00
US Classification:
514 11, 4241301, 4241341, 530350, 530351
Abstract:
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17F, IL-17A, or both IL-17A and IL-17F polypeptide molecules. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. ZcytoR14 is a common receptor for IL-17A and IL-17F. The present invention includes soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners, as well as methods for antagonizing IL-17F, IL-17A or both IL-17A and IL-17F using such soluble receptors, antibodies and binding partners.
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Rolf E Kuestner from Bothell, WA, age ~66 Get Report