Rodney C Schnur

RE41065, Dec 29, 2009

Feb 27, 2008

12/038530

Rodney Caughren Schnur - Noank CT, US
Lee Daniel Arnold - Mt. Sinai NY, US

Pfizer, Inc. - New York NY
OSI Pharmaceuticals, Inc. - Melville NY

C07D 239/94
C07D 239/70
A61K 31/517
A61P 17/06
A61P 35/00

5142661, 544293, 544283

The invention relates to compounds of the formula and to pharmaceutically acceptable salts thereof, wherein R, R, R, R, n and m are as defined herein. The compounds of formula I are useful in the treatment of hyperproliferative diseases, such as cancer. The invention further relates to processes of making the compounds of formula I and to methods of using such compounds in the treatment of hyperproliferative diseases.

42835399, Aug 11, 1981

Dec 18, 1979

6/104939

Rodney C. Schnur - Noank CT

Pfizer Inc. - New York NY

C07D21716
A61K 3147

546141

Novel isoquinoline acetic acids and derivatives thereof useful as aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications, especially diabetic cataracts are disclosed. Also disclosed are pharmaceutical compositions containing the novel compounds of this invention and a method of treatment of diabetic cataracts by administration of effective amounts of the novel compounds described herein.

57474982, May 5, 1998

May 28, 1996

8/653786

Rodney Caughren Schnur - Noank CT
Lee Daniel Arnold - Westborough MA

Pfizer Inc. - New York NY

A61K 31495
A61K 31505
C07D23970
C07D23994

514259

The invention relates to compounds of the formula ##STR1## and to pharmaceutically acceptable salts thereof, wherein R. sup. 1, R. sup. 2, R. sup. 3, R. sup. 4, n and m are as defined herein. The compounds of formula I are useful in the treatment of hyperproliferative diseases, such as cancer. The invention further relates to processes of making the compounds of formula I and to methods of using such compounds in the treatment of hyperproliferative diseases.

46893369, Aug 25, 1987

Oct 3, 1985

6/783982

Rodney C. Schnur - Noank CT

Pfizer Inc. - New York NY

C07D26344
A61K 3142

514376

Hypoglycemic 5-chromanyl, 2,3-dihydro-5-benzo[b]-furanyl, 5-pyridyl, 5-quinolyl, 5-pyrrolyl, 5-indolyl, 5-thiazolyl, 5-oxazolyl, 5-isothiazolyl and 5-isoxazolyl oxazolidine-2,4-diones and the pharmaceutically-acceptable salts thereof; certain 3-acylated derivatives thereof; a method of treating hyperglycemic animals therewith; and intermediates useful in the preparation of said compounds.

45658200, Jan 21, 1986

Jan 26, 1984

6/574236

Rodney C. Schnur - Noank CT

Pfizer Inc. - New York NY

A61K 3140
A61K 3147
C07D41102
C07D41304

514314

Hypoglycemic 5-chromanyl, 2,3-dihydro-5-benzo[b]-furanyl, 5-pyridyl, 5-quinolyl, 5-pyrrolyl, 5-indolyl, 5-thiazolyl, 5-oxazolyl, 5-isothiazolyl and 5-isoxazolyl oxazolidine-2,4-diones and the pharmaceutically-acceptable salts thereof; certain 3-acylated derivatives thereof; a method of treating hyperglycemic animals therewith; and intermediates useful in the preparation of said compounds.

40255557, May 24, 1977

Jul 23, 1976

5/708180

Allen R. Kraska - East Lyme CT
Rodney C. Schnur - Noank CT

Pfizer Inc. - New York NY

C07D12300

260564R

Novel [N,N-di(higher alkyl)aminomethyl]benzamidine and substituted compounds such as [N,N-di(higher alkyl)aminomethyl]-N-(2-propyl)-benzamidine and [N,N-di(higher alkyl)aminomethyl]-N-(p-hydroxyphenyl)-benzamidine and their non-toxic acid addition salts are useful for combating viral infections in vertebrate animals.

47539569, Jun 28, 1988

May 28, 1987

7/055498

Rodney C. Schnur - Noank CT

Pfizer Inc. - New York NY

A61K 3142
A61K 31425
C07D26334
C07D27732

514365

Hypoglycemic 5-chromanyl, 2,3-dihydro-5-benzo[b]-furanyl, 5-pyridyl, 5-quinolyl, 5-pyrrolyl, 5-indolyl, 5-thiazolyl, 5-oxazolyl, 5-isothiazolyl and 5-isoxazolyl oxazolidine-2,4-diones and the pharmaceutically-acceptable salts thereof; certain 3-acylated derivatives thereof; a method of treating hyperglycemic animals therewith; and intermediates useful in the preparation of said compounds.

46224068, Nov 11, 1986

Sep 17, 1985

6/777109

Rodney C. Schnur - Noank CT

Pfizer Inc. - New York NY

C07F 702
C07F 710

549 4

Hypoglycemic 5-furyl and 5-thienyl derivatives of oxazolidine-2,4-dione and the pharmaceutically-acceptable salts thereof; certain 3-acylated derivatives thereof; and intermediates useful in the preparation of said compounds.