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Roberta Pelanda

from Denver, CO
Age ~60
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Also known as:
Roberta P Torres, Elnada P Robertoa
Phone and address:
2245 Birch St, Denver, CO 80207
(720) 941-5776
Related to:
Raul C TurresMaria Beatriz Torres, 62Suzanne E Torres, 72Silvia N Porres, 68Nelly Y Torres, 96
Connected to:
Chad M Pelander, 45Laura E Pelanek, 45Jonathan M Pelanne, 40Jennifer A Pelant, 55Luke R Pelant, 29Robert Pelar, 46Galini E Pelarinos, 33Chaz A Pelas, 33Glen X Pelas, 48Nanci M Pelati, 59

Roberta Pelanda Phones & Addresses

  • 2245 Birch St, Denver, CO 80207 (720) 941-5776
  • Seattle, WA
  • 2245 Birch St, Denver, CO 80207

Work

Company: National jewish health Position: Associate professor

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Università Degli Studi Di Milano 1988 to 1992 Specialities: Molecular Biology, Philosophy

Skills

Cell Biology • Molecular Biology • Biochemistry • Science • Cell • Immunology

Emails

r***[email protected]

Industries

Hospital & Health Care

Resumes

Resumes

Roberta Pelanda Photo 1

Professor

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Location:
Denver, CO
Industry:
Hospital & Health Care
Work:
National Jewish Health
Associate Professor
Education:
Università Degli Studi Di Milano 1988 - 1992
Doctorates, Doctor of Philosophy, Molecular Biology, Philosophy Università Degli Studi Di Milano 1984 - 1988
Masters, Bachelors, Genetics
Skills:
Cell Biology
Molecular Biology
Biochemistry
Science
Cell
Immunology

Publications

Us Patents

Pulmonary Disease Treatment And Diagnosis Based On Arhgef1

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US Patent:
20130289121, Oct 31, 2013
Filed:
Jan 13, 2012
Appl. No.:
13/979410
Inventors:
Raul M. Torres - Denver CO, US
John Hartney - Arvada CO, US
Roberta Pelanda - Denver CO, US
Assignee:
The Regents of the University of Colorado, a body corporate - Denver CO
International Classification:
A61K 31/192
C12Q 1/68
G01N 33/577
US Classification:
514570, 435 612, 436501, 435 611
Abstract:
Treatment and diagnostic methods are provided for pulmonary disease, including chronic obstructive pulmonary disease, Arhgef1, a leukocyte signaling molecule, functions normally to suppress integrin-mediated MMP production by alveolar macrophages. MMP9 production by fibronectin-stimulated monocytes and macrophages depends on autocrine thromboxane receptor signaling and this signaling pathway is attenuated by Arhgef1. Expression of ARHGEF1 by human peripheral blood monocytes varies between individuals and inversely correlates with fibronectin-mediated MMP9 production. Arhgef1 levels can function as a predictor for a pulmonary disease candidate and a thromboxane receptor antagonist can treat a pulmonary disease condition resulting from low Arhgef1 levels.

Pro-Inflammatory Mediators In Diagnosis And Treatment Of Pulmonary Disease

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US Patent:
20150051259, Feb 19, 2015
Filed:
Apr 9, 2013
Appl. No.:
14/391484
Inventors:
- Boulder CO, US
- Denver CO, US
Roberta Pelanda - Denver CO, US
International Classification:
C12Q 1/68
US Classification:
514411, 435 612, 435 792, 514419, 514559, 514562
Abstract:
Treatment and diagnostic methods are provided for pulmonary disease, including chronic obstructive pulmonary disease. Various pro-inflammatory mediators are elevated in a model of COPD that can be used predict the presence of COPD and/or subtypes of COPD in human patients. Profiles of these mediators can also predict the responsiveness of some patients to certain therapies, including thromboxane receptor antagonist treatment. Methods are provided for diagnosing a subject as a pulmonary disease candidate that include determining leukocyte expression in the subject of at least one pro-inflammatory mediator and identifying the subject as a pulmonary disease candidate when leukocyte expression in the subject of the pro-inflammatory mediator is increased compared to leukocyte expression of the pro-inflammatory mediator in a healthy individual. The pulmonary disease candidate can also be treated by administering a therapeutically effective amount of a thromboxane receptor antagonist.
Control profile
Roberta Pelanda from Denver, CO, age ~60 Get Report