Robert L Webster

20070016067, Jan 18, 2007

May 19, 2006

11/436995

Robert Webster - Baltimore MD, US
Allison Okamura - Ruxton MD, US
Noah Cowan - Baltimore MD, US
Gregory Chirikjian - Towson MD, US
Kenneth Goldberg - San Francisco CA, US
Ron Alterovitz - Berkeley CA, US

THE JOHNS HOPKINS UNIVERSITY - Baltimore MD

A61B 8/14

600464000, 600562000

Disclosed is a system for percutaneously steering a surgical needle. Needle steering is accomplished by taking advantage of a deflection force imparted on the bevel tip of the needle by the tissue medium as the needle is pushed through the tissue. By controlling the translation speed and rotation angle of the bevel, a flexible needle may be steered substantially without deflecting or distorting the tissue. The control inputs (translation speed and rotation angle) are computed based on a “bicycle” non-holonomic kinematic model that is a function of mechanical properties of the tissue medium. The system may be used with image-based feedback, which may provide for feedback-based refinement of the model as the needle propagates through the tissue.

20130018303, Jan 17, 2013

Mar 9, 2012

13/416772

Robert James Webster - Baltimore MD, US
Allison M. Okamura - Towson MD, US
Noah J. Cowan - Baltimore MD, US
Russell H. Taylor - Severna Park MD, US

The Johns Hopkins University - Baltimore MD

A61M 25/092

604 9501

A method for guiding a surgical cannula having a plurality of overlapping flexible tubes includes determining a desired cannula path; selecting the plurality of flexible tubes, wherein each of the flexible tubes within the plurality has a pre-formed curvature and a flexibility; determining a final overlap configuration of the plurality of flexible tubes such that a resulting curvature of the overlap configuration substantially corresponds to the desired cannula path; and determining a plurality of intermediate overlap configurations of the plurality of flexible tubes. Each of the intermediate configurations correspond to the desired cannula path.

45527580, Nov 12, 1985

Dec 20, 1983

6/563372

Brian R. Murphy - Bethesda MD
Robert M. Chanock - Bethesda MD
Robert G. Webster - Memphis TN
Virginia S. Hinshaw - Germantown TN

St. Jude Children's Research Hospital - Memphis TN

A61K 39145

424 89

A method of producing a live attenuated vaccine useful in humans which comprises producing an influenza A reassortant virus by gene exchange between an avian influenza virus parent and a human influenza virus parent and then excluding the internal genes (that code for non-surface viral proteins) of the human influenza virus parent from the reassortant by temperature selection and excluding the surface antigen genes of the avian influenza A virus parent by antibodies.

45527571, Nov 12, 1985

Dec 20, 1983

6/563370

Brian R. Murphy - Bethesda MD
Robert M. Chanock - Bethesda MD
Robert G. Webster - Memphis TN
Virginia S. Hinshaw - Germantown TN

St. Jude Children's Research Hospital - Memphis TN

A61K 39145

424 89

A method of producing a vaccine useful in animals which comprises producing a reassortment by gene exchange from an avian influenza A virus parent and an animal influenza A virus parent and then selecting for the reassortant containing two animal surface antigen genes and six avian internal genes by temperature and antibodies.