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Robert A Terkeltaub

from San Diego, CA
Age ~73
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Also known as:
Robert B
Phone and address:
13211 Denara Rd, San Diego, CA 92130
Related to:
Barbara Nogal, 74Lillian Nogal
Connected to:
Brandi A Terkeurst, 44Monica Z Terkeurst, 52Bonnie K Terkhorn, 39Eugene M Terkoski, 36Michelle L Terkoski, 55Paul Terkun, 55Parker Terlaak, 39Sarah R Terlaga, 37Kenneth C Terlaje, 69Kathryn L Terlalis, 38

Robert Terkeltaub Phones & Addresses

  • 13211 Denara Rd, San Diego, CA 92130
  • 202 Village Run, Encinitas, CA 92024

Work

Company: VA Med Ctr San Diego Rhmtlgy Address: 3350 La Jolla Village Dr Suite 3221, San Diego, CA 92161 Phones: (858) 552-8585

Education

School / High School: University of California At San Diego

Languages

English

Awards

Healthgrades Honor Roll

Ranks

Certificate: Geriatric Medicine, 1992

Specialities

Geriatric Medicine • Rheumatology

Professional Records

Medicine Doctors

Robert Terkeltaub Photo 1

Dr. Robert Terkeltaub, San Diego CA - MD (Doctor of Medicine)

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Specialties:
Geriatric Medicine
Rheumatology
Address:
VA Med Ctr San Diego Rhmtlgy
3350 La Jolla Village Dr Suite 3221, San Diego, CA 92161
(858) 552-8585 (Phone)
Certifications:
Geriatric Medicine, 1992
Internal Medicine, 1981
Rheumatology, 1982
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
VA Med Ctr San Diego Rhmtlgy
3350 La Jolla Village Dr Suite 3221, San Diego, CA 92161

UCSD Medical Center - Hillcrest
200 West Arbor Drive, San Diego, CA 92103
Education:
Medical School
University of California At San Diego
Medical School
Montreal General Hospital
Robert Terkeltaub Photo 2

Robert Terkeltaub

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Specialties:
Rheumatology
Work:
VA Medical Center San Diego Rheumatology
3350 Ln Jolla Vlg Dr, San Diego, CA 92161
(858) 552-8585 (phone), (858) 552-7425 (fax)
Education:
Medical School
McGill University Faculty of Medicine, Montreal, Canada
Graduated: 1976
Procedures:
Arthrocentesis
Conditions:
Ankylosing Spondylitis (AS)
Gout
Acute Renal Failure
Carpel Tunnel Syndrome
Chronic Renal Disease
Languages:
English
Spanish
Description:
Dr. Terkeltaub graduated from the McGill University Faculty of Medicine, Montreal, Canada in 1976. He works in San Diego, CA and specializes in Rheumatology. Dr. Terkeltaub is affiliated with UCSD Medical Center and VA San Diego Healthcare System.
Robert Terkeltaub Photo 3

Robert Terkeltaub, San Diego CA

Work:
Va San Diego Healthcare System
3350 La Jolla Village Dr, San Diego, CA 92161

Business Records

Name / Title
Company / Classification
Phones & Addresses
Robert Abraham Terkeltaub
Robert Terkeltaub MD
Internist
3350 Ln Jolla Vlg Dr #111K, San Diego, CA 92161
(858) 642-3247

Publications

Us Patents

Compositions And Methods For Modulating Bone Mineral Deposition

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US Patent:
7888372, Feb 15, 2011
Filed:
Apr 28, 2003
Appl. No.:
10/426005
Inventors:
Jose Luis Millan - San Diego CA, US
Robert Terkeltaub - San Diego CA, US
Assignee:
National Institutes of Health (NIH) - Bethesda MD
The Regents of the University of California - Oakland CA
International Classification:
A01N 43/42
A01N 37/12
US Classification:
514310, 514565
Abstract:
The key function of TNAP in bone is degradation of PPi to remove this mineralization inhibitor and provide free phosphate for apatite deposition. PC-1 is a direct antagonist of TNAP function. ANK also antagonizes TNAP-dependent matrix calcification. Specifically, the activity of PC-1 inhibits initial MV apatite deposition, but ANK inhibits propagation of apatite outside the MVs. Furthermore, loss of function of the two distinct skeletal TNAP antagonists, PC-1 and ANK, ameliorates TNAP deficiency-associated osteomalacia in vivo. Conversely, the hyperossification associated with both PC-1 null mice and ANK-deficient (ank/ank) mice is ameliorated by deficiency of TNAP in vivo.

Compositions And Methods For Modulating Bone Mineral Deposition

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US Patent:
20020183276, Dec 5, 2002
Filed:
Mar 22, 2002
Appl. No.:
10/104482
Inventors:
Jose Millan - San Diego CA, US
Robert Terkeltaub - San Diego CA, US
Assignee:
Burnham Institute
International Classification:
A61K048/00
A61K031/198
A61K039/395
US Classification:
514/044000, 424/146100, 514/565000
Abstract:
The key function of TNAP in bone is degradation of PPi to remove this mineralization inhibitor and provide free phosphate for apatite deposition. PC-1 is a direct antagonist of TNAP function. ANK antagonizes TNAP-dependent matrix calcification. Specifically, the activity of PC-1 inhibits initial MV apatite deposition, but ANK inhibits propagation of apatite outside the MVs. Furthermore, loss of function of the two distinct skeletal TNAP antagonists, PC-1 and ANK, ameliorates TNAP deficiency-associated osteomalacia in vivo. Conversely, the hyperossification associated with both PC-1 null mice and ANK-deficient (ank/ank) mice is ameliorated by deficiency of TNAP in vivo.

Method For Inhibiting Articular Cartilage Matrix Calcification

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US Patent:
20040109845, Jun 10, 2004
Filed:
Sep 23, 2003
Appl. No.:
10/669540
Inventors:
Robert Terkeltaub - San Diego CA, US
International Classification:
A61K048/00
US Classification:
424/085200, 514/044000
Abstract:
Methods of inhibiting calcification in meniscal and articular cartilage of the joints are disclosed. The methods include blocking the activation and activity of transglutaminases tTGase and Factor XIIIa. Furthermore, disclosed are methods for identifying agents that affect TGase activity and/or matrix calcification.

Methods And Compositions For Diagnosing And Treating Arthritic Disorders And Regulating Bone Mass

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US Patent:
20070021496, Jan 25, 2007
Filed:
Jun 29, 2005
Appl. No.:
11/172386
Inventors:
Robert Terkeltaub - San Diego CA, US
Anne Murphy - Encinitas CA, US
James Dykens - Encinitas CA, US
Soumitra Ghosh - San Diego CA, US
Robert Davis - San Diego CA, US
Andrew Granston - San Diego CA, US
Assignee:
MIGENIX Corp. - San Diego CA
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA
International Classification:
A61K 31/365
US Classification:
514450000
Abstract:
The present invention relates to improved diagnostic methods for early detection of a risk for developing an arthritic disorder in humans, and screening assays for therapeutic agents useful in the treatment of arthritic disorders, by comparing the levels of one or more indicators of altered mitochondrial function. Indicators of altered mitochondrial function include enzymes such as mitochondrial enzymes and ATP biosynthesis factors. Other indicators of altered mitochondrial function include mitochondrial mass, mitochondrial number and mitochondrial DNA content, cellular responses to elevated intracellular calcium and to apoptogens, and free radical production. Methods of treating, and of stratifying, human patients as such methods relate to disclosed indicators of altered mitchondrial function are also provided.

Methods And Compositions For Diagnosing And Treating Arthritic Disorders And Regulating Bone Mass

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US Patent:
7005274, Feb 28, 2006
Filed:
Sep 14, 2000
Appl. No.:
09/661848
Inventors:
Robert Terkeltaub - San Diego CA, US
Anne N. Murphy - Encinitas CA, US
James A. Dykens - Encinitas CA, US
Soumitra S. Ghosh - San Diego CA, US
Robert E. Davis - San Diego CA, US
Assignee:
MIGENIX Corp. - San Diego CA
The Regents of the University of California - Oakland CA
International Classification:
C12Q 1/02
US Classification:
435 29, 435 32, 435375
Abstract:
The present invention relates to improved diagnostic methods for early detection of a risk for developing an arthritic disorder in humans, and screening assays for therapeutic agents useful in the treatment of arthritic disorders, by comparing the levels of one or more indicators of altered mitochondrial function. Indicators of altered mitochondrial function include enzymes such as mitochondrial enzymes and ATP biosynthesis factors. Other indicators of altered mitochondrial function include mitochondrial mass, mitochondrial number and mitochondrial DNA content, cellular responses to elevated intracellular calcium and to apoptogens, and free radical production. Methods of treating, and of stratifying, human patients as such methods relate to disclosed indicators of altered mitchondrial function are also provided.
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Robert A Terkeltaub from San Diego, CA, age ~73 Get Report