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Robert A Chrusciel

from Portage, MI
Age ~66
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Also known as:
Rob A Chrusciel, Bob A Chrusciel, Robert L
Phone and address:
519 Cherryview Dr, Kalamazoo, MI 49024
(269) 324-4345
Related to:
James E Parks, 85Nicki ChruscielFrank ChruscielSamuel Chrusciel, 36Nicole Chrusciel, 34
Connected to:
Adam T Chrusciel, 40David R Chrusciel, 56Laura A Chrusciel, 39Marc Chrusch, 70Melinda C Chruscial, 54Taylor E Chrusciel, 32Brenda J Chrustawka, 33Jocelyn S Chruszczak, 66Kelli Chrusz, 42Mark E Chrusz, 72

Robert Chrusciel Phones & Addresses

  • 519 Cherryview Dr, Portage, MI 49024 (269) 324-4345
  • 11949 Breezemont Dr, Maryland Heights, MO 63043
  • Barrington, IL
  • Libertyville, IL
  • Wauconda, IL
  • 519 Cherryview Dr, Portage, MI 49024 (616) 529-8845

Education

Degree: Graduate or professional degree

Emails

r***[email protected]

Resumes

Resumes

Robert Chrusciel Photo 1

Distinguished Scientist

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Location:
Kalamazoo, MI
Industry:
Pharmaceuticals
Work:
Kalexsyn since 2004
Senior Scientist
Upjohn 1993 - 2003
Research Scientist
Searle 1992 - 1993
Senior Research Investigator
Monsanto Corporate Research 1991 - 1992
Post Doctoral Research Associate
Universtity of Illinois at Chicago 1989 - 1991
Post Doctoral Research Associate
Education:
University of Illinois at Chicago 1981 - 1988
PhD, medicinal chemistry Purdue University 1976 - 1981
bs, Pharmacy
Skills:
Medicinal Chemistry
Drug Design
Drug Discovery
Organic Synthesis
Synthetic Organic Chemistry
Chromatography
Chemistry
Pharmaceutical Industry
Organic Chemistry
Life Sciences
High Performance Liquid Chromatography
Parallel Synthesis
Drug Development
Liquid Chromatography Mass Spectrometry
Robert Chrusciel Photo 2

Reiki Specialist

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Work:

Reiki Specialist
Robert Chrusciel Photo 3

Robert Chrusciel

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Robert Chrusciel Photo 4

Robert Chrusciel

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Publications

Us Patents

Inhibitors Of 41 Mediated Cell Adhesion

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US Patent:
6482849, Nov 19, 2002
Filed:
Jun 23, 1998
Appl. No.:
09/102584
Inventors:
Thomas J. Lobl - Foster City CA
Bradley R. Teegarden - San Diego CA
Alexander Polinsky - San Diego CA
Gilbert M. Rishton - Thousand Oaks CA
Masafumi Yamagishi - Hyogo-ken, JP
Steven Tanis - Kalamazoo MI
Jed F. Fisher - Three Rivers MI
Edward W. Thomas - Kalamazoo MI
Robert A. Chrusciel - Portage MI
Assignee:
Tanabe Seiyaku Co., Ltd. - Osaka
Pharmacia Upjohn Company - Kalamazoo MI
International Classification:
A61K 3127
US Classification:
514430, 514355, 514400, 514419, 514448, 514471, 514478, 514562, 514563, 514566, 546316, 5483381, 548495, 549 69, 549493, 560 13, 560 27, 560 41, 562430, 562432
Abstract:
The present invention relates to small molecules according to the formula [I]: which are potent inhibitors of mediated adhesion to either VCAM or CS-1 and which can be used for treating or preventing adhesion mediated conditions in a mammal such as a human.

Cyclic Sulfone Containing Retroviral Protease Inhibitors

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US Patent:
6552203, Apr 22, 2003
Filed:
Oct 11, 2001
Appl. No.:
09/973991
Inventors:
Deborah E. Bertenshaw - Brentwood MO
Daniel Getman - Chesterfield MO
Robert M. Heintz - Ballwin MO
John J. Talley - St. Louis MO
Kathryn L. Reed - Raleigh NC
Robert Alan Chrusciel - Portage MI
Michael Clare - Skokie IL
Assignee:
Monsanto Company - St. Louis MO
International Classification:
C07D49500
US Classification:
549 9, 549 13, 549 28, 549 72, 514431, 514432, 514445, 514446, 514448
Abstract:
The present invention relates to cyclic sulfone moiety-containing hydroxyethylamine protease inhibitor compounds and pharmaceutical or method of use therefor, particularly as an inhibitor of HIV protease.

Inhibitors Of 41 Mediated Cell Adhesion

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US Patent:
6596752, Jul 22, 2003
Filed:
Jul 12, 2002
Appl. No.:
10/193137
Inventors:
Thomas J. Lobl - Foster City CA
Bradley R. Teegarden - San Diego CA
Alexander Polinsky - San Diego CA
Gilbert M. Rishton - Thousand Oaks CA
Masafumi Yamagishi - Hyogo-ken, JP
Steven Tanis - Kalamazoo MI
Jed F. Fisher - Three Rivers MI
Edward W. Thomas - Kalamazoo MI
Robert A. Chrusciel - Portage MI
Assignee:
Tanabe Seiyaku Co., Ltd. - Osaka
Pharmacia Upjohn Company - Kalamazoo MI
International Classification:
A61K 31415
US Classification:
514401, 5142375, 514307, 514350, 514354, 514400, 514419, 514423, 514448, 514471, 514478, 514530, 514562, 514563, 514566, 544165, 546145, 546298, 546316, 546323, 5483381, 5483761, 548495, 548537, 549 69, 549487, 549493, 566 13, 566 27, 562430, 562432
Abstract:
The present invention relates to small molecules according to the formula [I]: which are potent inhibitors of mediated adhesion to either VCAM or CS-1 and which can be used for treating or preventing adhesion mediated conditions in a mammal such as a human.

Inhibitors Of 41 Mediated Cell Adhesion

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US Patent:
6685617, Feb 3, 2004
Filed:
Mar 9, 2001
Appl. No.:
09/720088
Inventors:
James Blinn - Lawton MI
Robert Chrusciel - Portage MI
Jed Fisher - Kalamazoo MI
Steven Tanis - Kalamazoo MI
Edward Thomas - Kalamazoo MI
Thomas Lobl - Foster City CA
Bradley Teegarden - San Diego CA
Assignee:
Pharmacia Upjohn Company - Kalamazoo MI
Tanabe Seiyaku Co., Ltd. - Osaka
International Classification:
A61K 31425
US Classification:
5142275, 5142278, 514365, 514371, 544 584, 548200
Abstract:
The present invention relates to compound of formula (I), that are potent inhibitors of mediated adhesion to either VCAM or CS-1 and which could be useful for the treatment of inflammatory diseases. Specifically, the molecules of the present invention can be used for treating or preventing adhesion mediated conditions in a mammal such as a human. This method may comprise administering to a mammal or a human patient an effective amount of the compound or composition as explained in the present specification.

Statine Derivatives For The Treatment Of Alzheimer's Disease

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US Patent:
6864290, Mar 8, 2005
Filed:
Jul 10, 2002
Appl. No.:
10/192424
Inventors:
Heinrich Josef Schostarez - Portage MI, US
Robert Alan Chrusciel - Portage MI, US
Assignee:
Pharmacia & Upjohn, LLP - Kalamazoo MI
International Classification:
A61K031/165
C07C235/06
US Classification:
514617, 564152, 564153
Abstract:
The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.

Cyclic Sulfone Containing Retroviral Protease Inhibitors

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US Patent:
6875790, Apr 5, 2005
Filed:
Feb 20, 2003
Appl. No.:
10/369197
Inventors:
Deborah E. Bertenshaw - Brentwood MO, US
Daniel Getman - Chesterfield MO, US
Robert M. Heintz - Ballwin MO, US
John J. Talley - St. Louis MO, US
Kathryn L. Reed - Raleigh NC, US
Robert Alan Chrusciel - Portage MI, US
Michael Clare - Skokie IL, US
Assignee:
G. D. Searle & Co. - Skokie IL
Pharmacia Corporation (Monsanto Corporation) - St. Louis MO
International Classification:
A61K031/38
A61K031/335
C07D215/16
C07D337/00
C07D335/02
US Classification:
514431, 514432, 514445, 514446, 514448, 549 9, 549 13, 549 28, 549 72, 546156
Abstract:
The present invention relates to cyclic sulfone moiety-containing hydroxyethylamine protease inhibitor compounds and pharmaceutical or method of use therefor, particularly as an inhibitor of HIV protease.

Aminediols For The Treatment Of Alzheimer's Disease

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US Patent:
6906104, Jun 14, 2005
Filed:
Jun 13, 2002
Appl. No.:
10/171343
Inventors:
Heinrich Josef Schostarez - Portage MI, US
Robert Alan Chrusciel - Portage MI, US
Assignee:
Pharmacia & Upjohn Company - Kalamazoo MI
International Classification:
A61K031/164
A61K031/166
A61K031/133
C07D235/26
C07D235/70
US Classification:
514649, 564297, 564300, 564306, 514615, 514645
Abstract:
The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.

Aza Hydroxylated Ethyl Amine Compounds

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US Patent:
6960664, Nov 1, 2005
Filed:
May 22, 2002
Appl. No.:
10/152601
Inventors:
Heinrich Schostarez - Portage MI, US
Robert Alan Chrusciel - Portage MI, US
Rebecca S. Centko - Portage MI, US
Assignee:
Pharmacia & UpJohn Company - Kalamazoo MI
International Classification:
C07D277/20
US Classification:
548195, 548190, 548193, 548194, 548196, 548200
Abstract:
Disclosed are compounds of formula: and pharmaceutically acceptable salts and esters thereof, useful in treating and/or preventing Alzheimer's disease and other similar diseases, wherein R, R, R, Rand Rare defined herein. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
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Robert A Chrusciel from Portage, MI, age ~66 Get Report