Inventors:
Edwin H. Kolodny - New York NY
Srinavasa Raghavan - North Brunswick NJ
Miguel Angel Gama Sosa - New York NY
Rita De Gasperi - New York NY
Assignee:
New York University - New York NY
International Classification:
G01N 3353
G01N 33537
G01N 33543
G01N 33564
Abstract:
A method for screening for, diagnosing, monitoring or staging of multiple sclerosis, HIV infection, rheumatoid arthritis or systemic lupus erythematosus in a subject, is based on the detection of IgG antibodies against the hydroxy-fatty acid form of sulfatide in a tissue or body fluid sample of the subject. The presence of such IgG levels substantially above those in healthy controls is indicative of an increased likelihood that the subject has one of such conditions.