Search

Richard D Swerdlow

from Rockville, MD
Age ~76
Get Report
Also known as:
Dick D Swerdlow, Rick D Swerdlow, Ronald Swerdlow, Richard W
Related to:
Elizabeth Swerdlow, 42Lee M SwerdlowBonnie M Swerdlow, 75Andrew L Swerdlow, 40Leonore M Swerdlow
Connected to:
Amy G Swerdlow, 102Anne Swerdloff, 72Carl N Swerdloff, 84Carter A Swerdlow, 53David F Swerdlow, 56Gina N Swerdloff, 46Jonathan Swerdlow, 73Marilyn Swerdlow, 78Mimi U Swerdlow, 72Robert A Swerdlow, 70

Richard Swerdlow Phones & Addresses

  • Rockville, MD
  • Silver Spring, MD
  • 207 Thaxton St, Gaithersburg, MD 20878 (301) 869-6242
  • West Chester, PA
  • 11424 Dorchester Ln, Rockville, MD 20852

Publications

Us Patents

Method Using Keyhole Limpet Hemocyanin Composition With Enhanced Immunogenic Activity

View page
US Patent:
58559191, Jan 5, 1999
Filed:
Mar 26, 1997
Appl. No.:
8/837498
Inventors:
Ray F. Ebert - Derwood MD
Richard D. Swerdlow - Silver Spring MD
Assignee:
PerImmune Holdings, Inc. - Rockville MD
International Classification:
A61K 3556
US Classification:
424547
Abstract:
The present intention is directed to a stabilized keyhole limpet hemocyanin (KLH) composition in which (i) its intact non-degraded subunit is approximately 400,000 in molecular weight based on SDS-PAGE analysis; and (ii) are contained at least about 50% didecameric or higher KLH multimers, based on sedimentation-equilibrium and/or sedimentation-velocity ultracentrifugation analyses. The KLH composition is stabilized at 4. degree. C. by dissolving and storing it in an isotonic buffer preferably containing calcium and magnesium. It is critical that the KLH not have been frozen or lyophilized during its preparation or storage. The KLH composition demonstrates enhanced immunogenic activity, particularly enhanced anti-tumor activity, which is reduced if the KLH is frozen or lyophilized. The KLH composition of the present invention exhibits enhanced anti-tumor activity in a murine bladder tumor model and thereby represents a new and useful anti-tumor immunotherapeutic agent.

Method For Treating Bladder Cancer With A Keyhole Limpet Hemocyanin Composition Having Enhanced Anti-Tumor Activity

View page
US Patent:
59814764, Nov 9, 1999
Filed:
Jan 20, 1998
Appl. No.:
9/009121
Inventors:
Ray F. Ebert - Derwood MD
Richard D. Swerdlow - Silver Spring MD
Assignee:
Perimmune Holdings, Inc. - Rockville MD
International Classification:
A61K 3816
US Classification:
514 8
Abstract:
The present invention is directed to a stabilized keyhole limpet hemocyanin (KLH) composition in which (i) its intact non-degraded subunit is approximately 400,000 in molecular weight based on SDS-PAGE analysis; and (ii) are contained at least about 50% didecameric or higher KLH multimers, based on sedimentation-equilibrium and/or sedimentation-velocity ultracentrifugation analyses. The KLH composition is stabilized at 4. degree. C. by dissolving and storing it in an isotonic buffer preferably containing calcium and magnesium. It is critical that the KLH not have been frozen or lyophilized during its preparation or storage. The KLH composition demonstrates enhanced immunogenic activity, particularly enhanced anti-tumor activity, which is reduced if the KLH is frozen or lyophilized. The KLH composition of the present invention exhibits enhanced anti-tumor activity in a murine bladder tumor model and thereby represents a new and useful anti-tumor immunotherapeutic agent.

Dacs Network Architecture

View page
US Patent:
59955040, Nov 30, 1999
Filed:
Jul 21, 1997
Appl. No.:
8/897457
Inventors:
Richard Swerdlow - Vienna VA
Assignee:
Lucent Technologies, Inc. - Murray Hill NJ
International Classification:
H04L 1250
H04J 302
H04J 304
US Classification:
370360
Abstract:
A method of controlling multiplexers and cross-connects on a telecommunications network to interconnect DS0 and/or wideband circuits is developed for a test range where a large number of circuits, perhaps several hundred. have to be reassigned every fifteen minutes. However, the method is sufficiently general to work for a variety of telecommunications networks. The method of the invention controls the OC-3 multiplexers and the cross-connects to connect a DS0 or DS1 from any feeder site on the range to a DS0 or DS1 at any other feeder site. In addition to the interconnection of DS0 and DS1 signals, the method includes the control needed to set up conference circuits, where many full duplex circuits (such as two-way voice circuits) are connected together; other one-to-many connections, and simplex circuits where a connection is one-way.

Method Of Treating Bladder Cancer With A Keyhole Limpet Hemocyanin Composition With Enhanced Anti-Tumor Activity

View page
US Patent:
54079128, Apr 18, 1995
Filed:
Apr 19, 1993
Appl. No.:
8/050697
Inventors:
Ray F. Ebert - Derwood MD
Richard D. Swerdlow - Silver Spring MD
Assignee:
Akzo, N.V. - Arnhem
International Classification:
A61K 3710
US Classification:
514 8
Abstract:
The present invention is directed to a stabilized keyhole limpet hemocyanin (KLH) composition in which (i) its intact non-degraded subunit is approximately 400,000 in molecular weight based on SDS-PAGE analysis; and (ii) are contained at least about 50% didecameric or higher KLH multimers, based on sedimentation-equilibrium and/or sedimentation-velocity ultracentrifugation analyses. The KLH composition is stabilized at 4. degree. C. by dissolving and storing it in an isotonic buffer preferably containing calcium and magnesium. It is critical that the KLH not have been frozen or lyophilized during its preparation or storage. The KLH composition demonstrates enhanced immunogenic activity, particularly enhanced anti-tumor activity, which is reduced if the KLH is frozen or lyophilized. The KLH composition of the present invention exhibits enhanced anti-tumor activity in a murine bladder tumor model and thereby represents a new and useful anti-tumor immunotherapeutic agent.
Control profile
Richard D Swerdlow from Rockville, MD, age ~76 Get Report