Search

Richard Charles Guenther

from Leesburg, FL
Age ~76
Get Report
Also known as:
Richard C Guenther, Richard L Guenther, Chuck Guenther, Charles Richard Guenther, Charles R Guenther, Richard Guenther See, Charles Guenther See
Phone and address:
22137 Draw Bridge Dr, Leesburg, FL 34748
Related to:
Robert Mccoy, 40Alexander R Yockey, 53David J Baker, 66Cassandra L Birtles, 54Ronnell D Baker, 69David A Baker, 48Jesse W Baker, 39Lynn C Hire, 39Andrew Yockey, 50Diana L Baker, 71Christina A Yockey, 76Steve Baker, 70Dianna L Baker, 74Francis A KalenaTyann GuentherAnne K Guenther, 62Brian D Baker, 63Retta M Kalena, 95
Connected to:
Amy K Guenther, 49Ben Guenther, 45Brendon M Guenther, 41Brittany A Guenther, 41Cheryl L Guenther, 65Cindy L Guenther, 50Clarence D Guenther, 67Corey L Guenther, 48Darla A Guenther, 75Daryl S Guenther, 73

Richard Guenther Phones & Addresses

  • 22137 Draw Bridge Dr, Leesburg, FL 34748
  • Chapel Hill, NC
  • Traverse City, MI
  • Clermont, FL
  • Maple City, MI
  • Waynesville, NC

Resumes

Resumes

Richard Guenther Photo 1

Richard Guenther

View page
Location:
United States

Business Records

Name / Title
Company / Classification
Phones & Addresses
Richard Howard Guenther
DESAPI AIR SERVICES, INC
Richard Guenther
PARADIGM AIRE INC

Publications

Wikipedia

Richard W. Guenther

View page

Richard William Guenther (November 30, 1845 April 5, 1913) was a Prussian- born 19th century politician and pharmacist in Wisconsin. Born in Potsdam ...

Richard Guenther House

View page

Richard Guenther House in Oshkosh, Wisconsin is a house built in 1888. It ...

Us Patents

Compositions And Methods For The Identification Of Inhibitors Of Protein Synthesis

View page
US Patent:
8232378, Jul 31, 2012
Filed:
Aug 24, 2009
Appl. No.:
12/546648
Inventors:
Richard H. Guenther - Cary NC, US
Winnell H. Newman - Cary NC, US
Samuel P. Yenne - Raleigh NC, US
Dan Mitchell - Raleigh NC, US
Andrzej Malkiewicz - Lodz, PL
Assignee:
Trana Discovery, Inc. - Cary NC
International Classification:
C07H 21/02
C07H 21/04
C12N 15/11
US Classification:
536 231
Abstract:
Compositions and methods for identifying inhibitors of RNA-target molecule interactions are provided as well as identifying inhibitors that block the role of tRNA in protein synthesis. The methods involve forming a mixture comprising a tRNA fragment molecule containing a modified nucleotide, a target molecule capable of binding to the tRNA fragment, and a test compound. The mixture is incubated under conditions that allow binding of the tRNA and the target molecule in the absence of the test compound. Assays can then be performed that detect whether or not the test compound inhibits the binding of the tRNA molecule and the target molecule. High throughput assays are also provided.

Compositions And Methods For The Identification Of Inhibitors Of Protein Synthesis

View page
US Patent:
8431341, Apr 30, 2013
Filed:
Jun 28, 2010
Appl. No.:
12/825114
Inventors:
Richard H. Guenther - Cary NC, US
Winnell H. Newman - Cary NC, US
Samuel P. Yenne - Raleigh NC, US
Dan Mitchell - Raleigh NC, US
Andrzej Malkiewicz - Lodz, PL
Assignee:
Trana Discovery, Inc. - Cary NC
International Classification:
C12Q 1/68
US Classification:
435 61
Abstract:
Compositions and methods for identifying inhibitors of RNA-target molecule interactions are provided as well as identifying inhibitors that block the role of tRNA in protein synthesis. The methods involve forming a mixture comprising a tRNA fragment molecule containing a modified nucleotide, a target molecule capable of binding to the tRNA fragment, and a test compound. The mixture is incubated under conditions that allow binding of the tRNA and the target molecule in the absence of the test compound. Assays can then be performed that detect whether or not the test compound inhibits the binding of the tRNA molecule and the target molecule. High throughput assays are also provided.

Biodegradable Non-Woven Fabric Having Plant Virus Encapsulated Actives For Drug Delivery

View page
US Patent:
8535727, Sep 17, 2013
Filed:
Feb 25, 2010
Appl. No.:
13/203017
Inventors:
Behnam Pourdeyhimi - Cary NC, US
Steve A. Lommel - Cary NC, US
Sara Honarbakhsh - Cincinnati OH, US
Ruben Carbonell - Raleigh NC, US
Richard H. Guenther - Cary NC, US
Assignee:
North Carolina State University - Raleigh NC
International Classification:
A61K 9/50
US Classification:
424501, 977773, 977802, 977805, 977906
Abstract:
A biodegradable delivery system for actives such as pharmaceutical drugs. The delivery system includes actives infused into the capsid of a purified plant virus. The loaded capsids are embedding in electrospun biodegradable polymer fibers, forming a nonwoven fabric.

Compositions And Methods For The Identification Of Inhibitors Of Protein Synthesis

View page
US Patent:
20080199870, Aug 21, 2008
Filed:
Nov 21, 2007
Appl. No.:
11/943924
Inventors:
Richard H. GUENTHER - Cary NC, US
Winnell H. Newman - Cary NC, US
Samuel P. Yenne - Cary NC, US
Dan Mitchell - Raleigh NC, US
Andrzej Malkiewicz - Lodz, PL
International Classification:
C12Q 1/68
C40B 40/06
C07H 21/04
US Classification:
435 6, 506 16, 536 221
Abstract:
Compositions and methods for identifying inhibitors of RNA-target molecule interactions are provided as well as identifying inhibitors that block the role of tRNA in protein synthesis. The methods involve forming a mixture comprising a tRNA fragment molecule containing a modified nucleotide, a target molecule capable of binding to the tRNA fragment, and a test compound. The mixture is incubated under conditions that allow binding of the tRNA and the target molecule in the absence of the test compound. Assays can then be performed that detect whether or not the test compound inhibits the binding of the tRNA molecule and the target molecule. High throughput assays are also provided.

Compositions And Methods For The Identification Of Inhibitors Of Retroviral Infection

View page
US Patent:
20100291032, Nov 18, 2010
Filed:
Sep 12, 2008
Appl. No.:
12/677819
Inventors:
Richard H. Guenther - Cary NC, US
Assignee:
TRANA DISCOVERY - Cary NC
International Classification:
A61K 38/21
C07H 21/02
A61K 31/7088
A61K 31/7105
C12Q 1/68
G01N 33/566
A61K 39/395
A61P 31/14
A61P 31/18
US Classification:
424 854, 536 231, 514 44 A, 514 44 R, 435 6, 436501, 4241311
Abstract:
Methods of identifying inhibitors of retroviral propagation, tRNA used in the methods, and kits, including the tRNA, which can be used in the methods, are disclosed. Methods of treating or preventing retroviral infections by administering an effective amount of the inhibitors, and pharmaceutical compositions including the inhibitors, are also disclosed. The methods involve forming a mixture comprising a linear sequence of a tRNA anticodon stem loop fragment that is not capable of forming a stem-loop, a target nucleic acid molecule capable of binding to the tRNA anticodon stem loop fragment, and a test compound. The mixture is incubated under conditions that allow binding of the tRNA anticodon stem loop fragment and the target nucleic acid molecule in the absence of the test compound. Assays can then be performed that detect whether or not the test compound inhibits the binding of the tRNA anticodon stem loop fragment and the target nucleic acid molecule.

Screening Methods For Identifying Specific Staphylococcus Aureus Inhibitors

View page
US Patent:
20110229920, Sep 22, 2011
Filed:
Sep 24, 2009
Appl. No.:
13/121381
Inventors:
Richard H. Guenther - Cary NC, US
Samuel P. Yenne - Raleigh NC, US
Assignee:
TRANA DISCOVERY, INC. - Cary NC
International Classification:
C12Q 1/42
C07H 21/02
C12N 9/00
C12N 9/08
C12N 9/16
C07H 21/00
G01N 33/48
C12Q 1/28
US Classification:
435 21, 536 231, 435183, 435192, 435196, 536 254, 436 94, 435 28
Abstract:
Methods of inhibiting propagation, and screening for compounds that inhibit propagation, are described. A method of inhibiting propagation comprises inhibiting ribosomal binding of a specific tRNA in the by an amount sufficient to inhibit protein expression. A method of screening for compounds useful for inhibiting propagation comprises contacting a specific tRNA to a ribosome that binds that tRNA in the presence of the test compound, and then determining whether the compound inhibits the binding of that tRNA.

Viral Nanoparticle Cell-Targeted Delivery Platform

View page
US Patent:
20120039799, Feb 16, 2012
Filed:
May 22, 2008
Appl. No.:
12/601736
Inventors:
Stefan Franzen - Apex NC, US
Richard Guenther - Cary NC, US
Steven A. Lommel - Cary NC, US
LiNa Loo - Monroe NJ, US
International Classification:
A61K 9/00
A61K 31/704
A61P 35/00
A61K 51/00
US Classification:
424 117, 424400, 514 34
Abstract:
This invention is a process for the manufacture of a plant viral capsid to be used for the targeted delivery of therapeutics to diseased cells. The process uses a plant virus as the starting material. The choice of the plant virus overcomes a problem in the manufacture of a uniform starting material. The final product has an advantage over other plant virus-based delivery systems in that the plant virus selected has a natural structure that is resistant to breakdown during the delivery process. This system takes advantage of the reversible divalent cation switch that this capsid employs to assemble and disassemble.

Antiviral Compounds And Methods Of Use Thereof

View page
US Patent:
20130071353, Mar 21, 2013
Filed:
Mar 14, 2011
Appl. No.:
13/634464
Inventors:
Richard H. Guenther - Cary NC, US
Jerzy R. Szewczyk - Chapel Hill NC, US
Assignee:
TRANA DISCOVERY, INC - Cary NC
International Classification:
A61K 48/00
A61K 31/5375
A61K 31/137
A61K 31/7088
A61K 39/395
A61K 31/437
A61K 31/517
A61K 31/4439
A61K 31/357
A61K 31/136
A61K 38/21
A61K 31/167
A61K 31/4245
A61K 31/451
A61K 31/40
A61K 31/515
A61K 31/4743
A61K 31/426
A61K 39/21
A61K 31/473
A61K 31/4745
A61K 38/19
US Classification:
424 854, 5142662, 514290, 514342, 514466, 514658, 514655, 514616, 514364, 514319, 514429, 5142395, 514270, 514291, 514369, 514285, 4241311, 514 44 A, 514 44 R
Abstract:
Inhibitors of retroviral propagation, methods of treatment and prevention of retroviral infections using the inhibitors, and pharmaceutical compositions including the inhibitors, are disclosed.
Control profile
Richard Charles Guenther from Leesburg, FL, age ~76 Get Report