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Reyna L Favis

from Phillipsburg, NJ
Age ~59
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Also known as:
Reynaldo L Favis, Reynaldo A Favis, Reynado L Favis, Reynold A Favis, Rey A Favis, Reyna Davis, Favis Reyna
Related to:
Aubrey Eugene Davis, 86Nicole G Davis, 53Johnnie A Davis, 48Bruce DavisMarian Davis
Connected to:
Carlo Favis, 47John J Favis, 43Jose C Favis, 45Michelle L Favitta, 44Samantha A Favitta, 52Rudolph A Favocci, 70Shannon K Favole, 54Boris H Favor, 51Evonnia Favor, 53Larry J Favor, 69

Reyna Favis Phones & Addresses

  • Phillipsburg, NJ
  • Iselin, NJ
  • Forked River, NJ
  • Edison, NJ
  • Newton, NJ
  • Radford, VA
  • Middletown, CT
  • Newton, MA

Work

Company: Janssen pharmaceutical companies of johnson & johnson 2011 Position: Scientific director

Education

Degree: Ph.D. School / High School: Wesleyan University 1986 to 1993 Specialities: Biology

Industries

Pharmaceuticals

Resumes

Resumes

Reyna Favis Photo 1

Scientific Director At Janssen Pharmaceutical Companies Of Johnson & Johnson

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Position:
Scientific Director at Janssen Pharmaceutical Companies of Johnson & Johnson
Location:
Greater New York City Area
Industry:
Pharmaceuticals
Work:
Janssen Pharmaceutical Companies of Johnson & Johnson since 2011
Scientific Director
Johnson & Johnson Pharmaceutical Research & Development 2008 - 2011
Director Clinical R&D
Johnson & Johnson Pharmaceutical Research and Development 2007 - 2008
Research Fellow
Johnson & Johnson Pharmaceutical Research and Development Feb 2005 - Feb 2007
Principal Scientist
Johnson & Johnson Pharmaceutical Research & Development 2002 - 2005
Senior Scientist
Education:
Wesleyan University 1986 - 1993
Ph.D., Biology Rensselaer Polytechnic Institute 1982 - 1986
B.S., Biology

Publications

Us Patents

Method Of Designing Addressable Array Suitable For Detection Of Nucleic Acid Sequence Differences Using Ligase Detection Reaction

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US Patent:
8492085, Jul 23, 2013
Filed:
Oct 15, 2008
Appl. No.:
12/252169
Inventors:
Francis Barany - New York NY, US
Monib Zirvi - Monmouth Junction NJ, US
Norman P. Gerry - Philadelphia PA, US
Reyna Favis - Iselin NJ, US
Richard Kliman - Iselin NJ, US
Assignee:
Cornell Research Foundation, Inc. - Ithaca NY
International Classification:
C12Q 1/68
C12M 1/00
C12M 1/34
C12M 3/00
US Classification:
435 61, 4352831, 4352872
Abstract:
The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with little mismatch, where the plural capture oligonucleotide probes have melting temperatures within a narrow range. The first step of the method involves providing a first set of a plurality of tetramers of four nucleotides linked together, where (1) each tetramer within the first set differs from all other tetramers in the first set by at least two nucleotide bases, (2) no two tetramers within the first set are complementary to one another, (3) no tetramers within the first set are palindromic or dinucleotide repeats, and (4) no tetramer within the first set has one or less or three or more G or C nucleotides. Groups of 2 to 4 of the tetramers from the first set are linked together to form a collection of multimer units. From the collection of multimer units, all multimer units formed from the same tetramer and all multimer units having a melting temperature in. degree. C.

Method Of Designing Addressable Array For Detection Of Nucleic Acid Sequence Differences Using Ligase Detection Reaction

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US Patent:
20050142543, Jun 30, 2005
Filed:
Apr 4, 2001
Appl. No.:
10/257158
Inventors:
Francis Barany - New York NY, US
Monib Zirvi - Willingboro NJ, US
Norman Gerry - Boston MA, US
Reyna Favis - Iselin NJ, US
Richard Kliman - Iselin NJ, US
International Classification:
C12Q001/68
C12P019/34
US Classification:
435006000, 435091200
Abstract:
The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with little mismatch, where the plural capture oligonucleotide probes have melting temperatures within a narrow range. The first step of the method involves providing a first set of a plurality of tetramers of four nucleotides linked together, where (1) each tetramer within the set differs from all other tetramers in the set by at least two nucleotide bases, (2) no two tetramers within a set are complementary to one another, (3) no tetramers within a set are palindromic or dinucleotide repeats, and (4) no tetramer within a set has one or less or three or more G or C nucleotides. Groups of 2 to 4 of the tetramers from the first set are linked together to form a collection of multimer units. From the collection of multimer units, all multimer units formed from the same tetramer and all multimer units having a melting temperature in C. of less than 4 times the number of tetramers forming a multimer unit are removed to form a modified collection of multimer units. The modified collection of multimer units is arranged in a list in order of melting temperature. The order of the modified collection of multimer units is randomized in 2 C. increments of melting temperature.

Biomarkers For Assessing Peripheral Neuropathy Response To Cancer Treatment

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US Patent:
20100249065, Sep 30, 2010
Filed:
Mar 24, 2010
Appl. No.:
12/730587
Inventors:
Nadine Cohen - Princeton NJ, US
Reyna Favis - Phillipsburg NJ, US
Qingqin Li - Flemington NJ, US
Deborah Ricci - Ringoes NJ, US
Yu Sun - Belle Mead NJ, US
Helgi van de Velde - Retie, BE
International Classification:
A61K 31/69
A61P 35/00
C12Q 1/68
US Classification:
514 64, 435 6
Abstract:
The present invention provides methods for identifying patients at increased risk of developing an adverse neurological event in response to a cancer treatment. Methods also include modifying the treatment regimen of said patent dependent on the presence or absence of biomarkers in the patient.

Detection Of Human Umbilical Cord Tissue Derived Cells

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US Patent:
20130190201, Jul 25, 2013
Filed:
Dec 20, 2012
Appl. No.:
13/722849
Inventors:
Advanced Technologies and Regenerative Medicine, LLC - Raynham MA, US
Reyna L. Favis - Phillipsburg NJ, US
Xiang Yao - San Diego CA, US
Yu Sun - Belle Mead NJ, US
Anthony J. Kihm - Princeton NJ, US
Stefanie Rassnick - Fort Washington PA, US
Assignee:
Advanced Technologies and Regenerative Medicine, LLC - Raynham MA
International Classification:
C12Q 1/68
G01N 33/68
US Classification:
506 9, 435 721, 435 612
Abstract:
The invention relates to methods for detecting allogeneic therapeutic cells (such as human umbilical cord tissue-derived cells (hUTC)) in blood. The methods includes the steps of identifying one or more one or more markers positive for allogeneic therapeutic cells (e.g. hUTC) and one or more markers positive for human peripheral blood mononuclear cells (PBMC); providing a blood sample from a patient that has been treated with allogeneic therapeutic cells (e.g. hUTC), analyzing the sample using an assay method to detect one or more markers positive for PBMC and one or more markers positive for allogeneic therapeutic cells (e.g. hUTC); and distinguishing between the PBMC and one or more markers positive for allogeneic therapeutic cells (e.g. hUTC). In one embodiment, the cells are hUTC and the markers positive of hUTC include CD10 and/or CD13 and the one or more markers positive for PBMC includes CD45.

Method Of Designing Addressable Array Suitable For Detection Of Nucleic Acid Sequence Differences Using Ligase Detection Reaction

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US Patent:
20130345072, Dec 26, 2013
Filed:
Jul 22, 2013
Appl. No.:
13/947777
Inventors:
Monib Zirvi - Monmouth Junction NJ, US
Norman P. Gerry - Philadelphia PA, US
Reyna Favis - Iselin NJ, US
Richard Kliman - Iselin NJ, US
Assignee:
Cornell Research Foundation, Inc. - Ithaca NY
International Classification:
C12Q 1/68
US Classification:
506 3
Abstract:
The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with little mismatch, where the plural capture oligonucleotide probes have melting temperatures within a narrow range. The first step of the method involves providing a first set of a plurality of tetramers of four nucleotides linked together, where (1) each tetramer within the set differs from all other tetramers in the set by at least two nucleotide bases, (2) no two tetramers within a set are complementary to one another, (3) no tetramers within a set are palindromic or dinucleotide repeats, and (4) no tetramer within a set has one or less or three or more G or C nucleotides. Groups of 2 to 4 of the tetramers from the first set are linked together to form a collection of multimer units. From the collection of multimer units, all multimer units formed from the same tetramer and all multimer units having a melting temperature in C. of less than 4 times the number of tetramers forming a multimer unit are removed to form a modified collection of multimer units. The modified collection of multimer units is arranged in a list in order of melting temperature. The order of the modified collection of multimer units is randomized in 2 C. increments of melting temperature. Alternating multimer units in the list are then divided into first and second subcollections, each arranged in order of melting temperature. After the order of the second subcollection is inverted, the first collection is linked in order to the inverted second collection to form a collection of double multimer units. From the collection of double multimer units, those units (1) having a melting temperature in C. less than 11 times the number of tetramers and more than 15 times the number of tetramers, (2) double multimer units with the same 3 tetramers linked together, and (3) double multimer units with the same 4 tetramers linked together with or without interruption are removed, to form a modified collection of double multimer units. The modified collection of double multimers can be immobilized on a support and used to capture, by hybridization, the products of a ligation detection reaction. As a result, the output of a ligation detection reaction, which is useful in detecting single-base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences, can be formatted on a support.

Method Of Designing Addressable Array Suitable For Detection Of Nucleic Acid Sequence Differences Using Ligase Detection Reaction

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US Patent:
20180002744, Jan 4, 2018
Filed:
Jul 7, 2017
Appl. No.:
15/644273
Inventors:
- Ithaca NY, US
Monib ZIRVI - Monmouth Junction NJ, US
Norman P. GERRY - Philadelphia PA, US
Reyna FAVIS - Iselin NJ, US
Richard KLIMAN - Iselin NJ, US
International Classification:
C12Q 1/68
Abstract:
The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with little mismatch, where the plural capture oligonucleotide probes have melting temperatures within a narrow range. The present invention further relates to an oligonucleotide array comprising of a support with the plurality of oligonucleotide probes immobilized on the support, a method of using the support to detect single-base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences, and a kit for such detection, which includes the support on which the oligonucleotides have been immobilized.

Detection Of Human Umbilical Cord Tissue-Derived Cells

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US Patent:
20170335409, Nov 23, 2017
Filed:
Mar 31, 2017
Appl. No.:
15/476460
Inventors:
- Raynham MA, US
Reyna L. Favis - Phillipsburg NJ, US
Xiang Yao - San Diego CA, US
Yu Sun - Belle Mead NJ, US
Anthony J. Kihm - Princeton NJ, US
Stefanie Rassnick - Fort Washington PA, US
Assignee:
DEPUY SYNTHES PRODUCTS, INC. - Raynham MA
International Classification:
C12Q 1/68
G01N 33/569
G01N 33/68
Abstract:
The invention relates to methods for detecting allogeneic therapeutic cells (such as human umbilical cord tissue-derived cells (hUTC)) in blood. The methods includes the steps of identifying one or more one or more markers positive for allogeneic therapeutic cells (e.g. hUTC) and one or more markers positive for human peripheral blood mononuclear cells (PBMC); providing a blood sample from a patient that has been treated with allogeneic therapeutic cells (e.g. hUTC), analyzing the sample using an assay method to detect one or more markers positive for PBMC and one or more markers positive for allogeneic therapeutic cells (e.g. hUTC); and distinguishing between the PBMC and one or more markers positive for allogeneic therapeutic cells (e.g. hUTC). In one embodiment, the cells are hUTC and the markers positive of hUTC include CD10 and/or CD13 and the one or more markers positive for PBMC includes CD45.

Method Of Designing Addressable Array Suitable For Detection Of Nucleic Acid Sequence Differences Using Ligase Detection Reaction

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US Patent:
20160215329, Jul 28, 2016
Filed:
Apr 12, 2016
Appl. No.:
15/096446
Inventors:
- Ithaca NY, US
Monib ZIRVI - Monmouth Junction NJ, US
Norman P. GERRY - Philadelphia PA, US
Reyna FAVIS - Iselin NJ, US
Richard KLIMAN - Iselin NJ, US
International Classification:
C12Q 1/68
Abstract:
The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with little mismatch, where the plural capture oligonucleotide probes have melting temperatures within a narrow range. The present invention further relates to an oligonucleotide array comprising of a support with the plurality of oligonucleotide probes immobilized on the support, a method of using the support to detect single-base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences, and a kit for such detection, which includes the support on which the oligonucleotides have been immobilized.
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Reyna L Favis from Phillipsburg, NJ, age ~59 Get Report