Raymond G Lovey

6403564, Jun 11, 2002

Oct 14, 1999

09/417884

Ashit K. Ganguly - Upper Montclair NJ
Jinping McCormick - Edison NJ
Raymond G. Lovey - West Caldwell NJ
Frank Bennett - Piscataway NJ
Anil K. Saksena - Upper Montclair NJ
Viyyoor M. Girijavallabhan - Parsippany NJ

Schering Corporation - Kenilworth NJ

A01N 4304

514 43, 514 2, 514383, 514894, 530351, 424 854, 424 857, 5482668

A method for treating a patient having chronic hepatitis C infection to eradicate detectable HCV-RNA involving a combination therapy using a therapeutically effective amount of ribavirin derivative of formula I and a therapeutically effective amount of interferon-alpha for a time period of from 20 up to 80 weeks.

6673775, Jan 6, 2004

Apr 18, 2001

09/837609

Ashit K. Ganguly - Upper Montclair NJ
Jinping McCormick - Edison NJ
Raymond G. Lovey - West Caldwell NJ
Frank Bennett - Piscataway NJ
Anil K. Saksena - Upper Montclair NJ
Viyyoor M. Girijavallabhan - Parsippany NJ

Schering Corporation - Kenilworth NJ

A01N 4304

514 43, 514 2, 514 21, 514894, 429 857, 429 854, 530351

Ribavirin derivatives represented by formula I wherein at least one of R , R or R is a straight or branched chain polyalkylene oxide polymer conjugate, and pharmaceutical compositions containing them as well as their use to treat patients having susceptible viral infections, alone and in combination with a therapeutically effective amount of interferon-alpha are disclosed.

6800434, Oct 5, 2004

Jul 19, 2001

09/909062

Anil K. Saksena - Upper Montclair NJ
Viyyoor Moopil Girijavallabhan - Parsippany NJ
Raymond G. Lovey - West Caldwell NJ
Edwin Jao - Warren NJ
Frank Bennett - Piscataway NJ
Jinping L. McCormick - Edison NJ
Haiyan Wang - Cranbury NJ
Russell E. Pike - Stanhope NJ
Stephane L. Bogen - Somerset NJ
Yi-Tsung Liu - Morris Township NJ
Ashok Arasappan - Bridgewater NJ
Tejal Parekh - Mountain View CA
Patrick A. Pinto - Morris Plains NJ
F. George Njoroge - Warren NJ
Ashit K. Ganguly - Upper Montclair NJ
Terence K. Brunck - Santa Fe NM
Scott Jeffrey Kemp - San Diego CA
Odile Esther Levy - San Diego CA
Marguerita Lim-Wilby - La Jolla CA

Schering Corporation - Kenilworth NJ
Dendreon Corporation - Seattle WA

A61K 3800

435 5, 435 6, 435 23, 514 9, 514 17, 514 18, 514160, 424 854, 530324, 530325, 530326, 530327, 530328, 530329

The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such peptides as well as methods of using them to treat disorders associated with the HCV protease.

6894072, May 17, 2005

Jan 21, 2003

10/348094

Ashok Arasappan - Bridgewater NJ, US
Frank Bennett - Cranford NJ, US
Stephane L. Bogen - Somerset NJ, US
Kevin X. Chen - Edison NJ, US
Edwin Jao - Warren NJ, US
Yi-Tsung Liu - Morris Township NJ, US
Raymond G. Lovey - West Caldwell NJ, US
Vincent S. Madison - Mountain Lakes NJ, US
Latha G. Nair - Edison NJ, US
F. George Njoroge - Warren NJ, US
Anil K. Saksena - Upper Montclair NJ, US
Mousumi Sannigrahi - Summit NJ, US
Srikanth Venkatraman - Woodbrige NJ, US
Viyyoor M. Girijavallabhan - Parsippany NJ, US

Schering Corporation - Kenilworth NJ

A61K031/403
C07D209/02
C07D403/12

514422, 548465, 548469, 548537, 548950, 546192, 544359, 514423

The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

6911428, Jun 28, 2005

Dec 10, 2001

10/013071

Zhaoning Zhu - East Windsor NJ, US
Srikanth Venkatraman - Woodbridge NJ, US
F. George Njoroge - Warren NJ, US
Ashok Arasappan - Bridgewater NJ, US
Bruce A. Malcolm - Westfield NJ, US
Viyyoor M. Girijavallabhan - Parsippany NJ, US
Raymond G. Lovey - West Caldwell NJ, US
Kevin X. Chen - Iselin NJ, US

Schering Corporation - Kenilworth NJ

A61K038/17
A61K031/33
C07K007/64

514 9, 530317, 540455, 514183

The present invention is directed to certain diaryl amide compounds as NS3-Serine protease inhibitors of hepatitis C virus. A particularly preferred compound is of the formula:.

6924270, Aug 2, 2005

Apr 18, 2001

09/837491

Ashit K. Ganguly - Upper Montclair NJ, US
Jinping Mc Cormick - Edison NJ, US
Raymond G. Lovey - West Caldwell NJ, US
Frank Bennett - Piscataway NJ, US
Anil K. Saksena - Upper Montclair NJ, US
Viyyoor M. Girijavallabhan - Parsippany NJ, US

Schering Corporation - Kenilworth NJ

A01N043/04
A61K031/70

514 43, 424 857, 424 854, 530351, 514 2, 514 21, 514894, 536 286, 536 287

Ribavirin derivatives represented by the formula II, pharmaceutical compositions containing them as well as methods of using the ribavirin derivatives represented by the formula II for the treatment of susceptible viral infections, for example, chronic hepatitis C infections administrating, the ribavirin derivatives being represented by formula II are disclosed.

7012066, Mar 14, 2006

Jul 19, 2001

09/908955

Anil K. Saksena - Upper Montclair NJ, US
Viyyoor Moopil Girijavallabhan - Parsippany NJ, US
Raymond G. Lovey - West Caldwell NJ, US
Edwin Jao - Warren NJ, US
Frank Bennett - Piscataway NJ, US
Jinping L. Mc Cormick - Edison NJ, US
Haiyan Wang - Cranbury NJ, US
Russell E. Pike - Stanhope NJ, US
Stephane L. Bogen - Somerset NJ, US
Tin-Yau Chan - Edison NJ, US
Yi-Tsung Liu - Morris Township NJ, US
Zhaoning Zhu - East Windsor NJ, US
F. George Njoroge - Warren NJ, US
Ashok Arasappan - Bridgewater NJ, US
Tejal Parekh - Mountain View CA, US
Ashit K. Ganguly - Upper Montclair NJ, US
Kevin X. Chen - Iselin NJ, US
Srikanth Venkatraman - Fords NJ, US
Henry A. Vaccaro - South Plainfield NJ, US
Patrick A. Pinto - Morris Plains NJ, US
Bama Santhanam - Bridgewater NJ, US
Scott Jeffrey Kemp - San Diego CA, US
Odile Esther Levy - San Diego CA, US
Marguerita Lim-Wilby - La Jolla CA, US
Susan Y. Tamura - Santa Fe NM, US
Wanli Wu - Edison NJ, US
Siska Hendrata - Edison NJ, US
Yuhua Huang - Scotch Plains NJ, US

Schering Corporation - Kenilworth NJ
Dendreon Corporation - Seattle WA

A61K 38/07
A61K 38/06
C07K 5/08
C07K 5/10

514 18, 530330, 530331

The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

7115578, Oct 3, 2006

Jul 6, 2004

10/885374

Ashit K. Ganguly - Upper Montclair NJ, US
Jinping McCormick - Edison NJ, US
Raymond G. Lovey - West Caldwell NJ, US
Frank Bennett - Cranford NJ, US
Anil K. Saksena - Upper Montclair NJ, US
Viyyoor M. Girijavallabhan - Parsippany NJ, US

Schering Corporation - Kenilworth NJ

A01N 43/04
A61K 31/70

514 43, 514 2, 514 21, 514894, 424 857, 424 854, 530351

Ribavirin derivatives represented by the formula V, pharmaceutical compositions containing them as well as the use of the ribavirin derivatives represented by the formula V for the preparation of a medicament for the treatment of susceptible viral infections, for example, chronic hepatitis C infections administrating, the ribavirin derivatives being represented by formula V.