Search

Randy Berka Phones & Addresses

  • Woodland, CA
  • 3609 Modoc Pl, Davis, CA 95618 (530) 753-9914
  • San Mateo, CA
  • Aurora, CO
  • 3609 Modoc Pl, Davis, CA 95618 (650) 346-4696

Work

Company: Archer daniels midland company Jul 2017 Position: Research fellow

Education

Degree: Doctorates, Doctor of Philosophy School / High School: University of Colorado Anschutz Medical Campus 1979 to 1983 Specialities: Microbiology, Immunology

Skills

Genomics • Microbiology • Biotechnology • Genetics • Molecular Biology • Systems Biology • Biochemistry • Protein Chemistry • Biology • Protein Purification • Protein Expression • Bioinformatics • Science • Dna • Pcr • Chromatography • Cell Biology • Proteomics • Technology Transfer • Sequence Analysis • Purification • Dna Sequencing • Molecular Cloning • Molecular Genetics • Cell • Assay Development • Microarray Analysis • Cell Culture • Comparative Genomics • Sds Page • Metabolic Engineering • Rt Pcr • Sequencing • Lifesciences • Functional Genomics • Hplc • Recombinant Dna Technology • Immunology • Western Blotting • Elisa • Qpcr • Microscopy • Transcriptomics • Drug Discovery • Gel Electrophoresis • Biopharmaceuticals • Fluorescence • Computational Biology • Immunohistochemistry • Transfection

Emails

Industries

Research

Resumes

Resumes

Randy Berka Photo 1

Research Fellow

View page
Location:
Davis, CA
Industry:
Research
Work:
Archer Daniels Midland Company
Research Fellow

Novozymes Apr 1992 - Jun 2017
Research Fellow, Integrative Biology

Bioag Alliance 2014 - 2014
Integrative Biology

Novo Nordisk Biotech 1992 - 2000
Research Manager

Genencor, A Danisco Division 1985 - 1992
Staff Scientist
Education:
University of Colorado Anschutz Medical Campus 1979 - 1983
Doctorates, Doctor of Philosophy, Microbiology, Immunology
Drake University 1977 - 1979
Masters, Master of Arts, Biology
University of Iowa 1973 - 1977
Bachelors, Bachelor of Science, Microbiology
Skills:
Genomics
Microbiology
Biotechnology
Genetics
Molecular Biology
Systems Biology
Biochemistry
Protein Chemistry
Biology
Protein Purification
Protein Expression
Bioinformatics
Science
Dna
Pcr
Chromatography
Cell Biology
Proteomics
Technology Transfer
Sequence Analysis
Purification
Dna Sequencing
Molecular Cloning
Molecular Genetics
Cell
Assay Development
Microarray Analysis
Cell Culture
Comparative Genomics
Sds Page
Metabolic Engineering
Rt Pcr
Sequencing
Lifesciences
Functional Genomics
Hplc
Recombinant Dna Technology
Immunology
Western Blotting
Elisa
Qpcr
Microscopy
Transcriptomics
Drug Discovery
Gel Electrophoresis
Biopharmaceuticals
Fluorescence
Computational Biology
Immunohistochemistry
Transfection

Publications

Us Patents

Promoters For Expressing Genes In A Fungal Cell

View page
US Patent:
6361973, Mar 26, 2002
Filed:
Mar 22, 2000
Appl. No.:
09/534407
Inventors:
Randy M. Berka - Davis CA
Michael W. Rey - Davis CA
Kimberly Brown - Elk Grove CA
Stephen H. Brown - Davis CA
Assignee:
Novozymes Biotech, Inc. - Davis CA
International Classification:
C12P 2102
US Classification:
435 691, 536 241
Abstract:
The present invention relates to methods for producing a polypeptide, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first nucleic acid sequence encoding the polypeptide operably linked to a second nucleic acid sequence comprising a promoter foreign to the nucleic acid sequence, wherein the promoter comprises a sequence selected from the group consisting of nucleotides 1 to 3949 of SEQ ID NO:1, nucleotides 1 to 938 of SEQ ID NO:2, and nucleotides 1 to 3060 of SEQ ID NO:3, and a subsequence thereof; and mutant, hybrid, and tandem promoters thereof; and (b) isolating the polypeptide from the cultivation medium. The present invention also relates to the isolated promoter sequences and to constructs, vectors, and fungal host cells comprising the promoter sequences operably linked to nucleic acid sequences encoding polypeptides.

Heterologous Polypeptides Expressed In Filamentous Fungi, Processes For Making Same, And Vectors For Making Same

View page
US Patent:
6379928, Apr 30, 2002
Filed:
Dec 10, 1999
Appl. No.:
09/468265
Inventors:
Randy Michael Berka - San Mateo CA
Daniel Cullen - Madison WI
Gregory Lawrence Gray - South San Francisco CA
Kirk James Hayenga - Burlingame CA
Virgil Bryan Lawlis - San Mateo CA
Assignee:
Genencor International, Inc. - Palo Alto CA
International Classification:
C12P 2100
US Classification:
435 711, 435 691, 435 697, 435 698, 435183, 435205, 435223, 435225, 43525411, 4352543, 4352544, 4352546, 4352548
Abstract:
Novel vectors are disclosed for expressing and secreting heterologous polypeptides from filamentous fungi. Such vectors are used in novel processes to express and secrete such heterologous polypeptides. The vectors used for transforming a filamentous fungus to express and secrete a heterologous polypeptide include a DNA sequence encoding a heterologous polypeptide and a DNA sequence encoding a signal sequence which is functional in a secretory system in a given filamentous fungus and which is operably linked to the sequence encoding the heterologous polypeptide. Such signal sequences may be the signal sequence normally associated with the heterologous polypeptides or may be derived from other sources. The vector may also contain DNA sequences encoding a promoter sequence which is functionally recognized by the filamentous fungus and which is operably linked to the DNA sequence encoding the signal sequence. Preferably functional polyadenylation sequences are operably linked to the 3â terminus of the DNA sequence encoding the heterologous polypeptides.

Polypeptides Having Lactonohydrolase Activity And Nucleic Acids Encoding Same

View page
US Patent:
6395529, May 28, 2002
Filed:
Nov 5, 1999
Appl. No.:
09/434690
Inventors:
Randy M. Berka - Davis CA
Michael W. Rey - Davis CA
Assignee:
Novozymes Biotech, Inc. - Davis CA
International Classification:
C12N 916
US Classification:
435197, 4352523, 4353201, 435929, 536 232, 530350
Abstract:
The present invention relates to isolated polypeptides having lactonohydrolase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides. The present invention further relates to methods for preventing microbial biofilm development.

Polypeptides Having Lysophospholipase Activity And Nucleic Acids Encoding Same

View page
US Patent:
6489154, Dec 3, 2002
Filed:
Nov 10, 1999
Appl. No.:
09/437687
Inventors:
Randy M. Berka - Davis CA
Michael W. Rey - Davis CA
Tony Byun - Davis CA
Ryoko Itami - Sukagawa, JP
Noriko Tsutsumi - Ichikawa, JP
Alan Klotz - Dixon CA
Assignee:
Novozymes Biotech, Inc. - Davis CA
Novozymes Bioindustry, Ltd.
International Classification:
C12N 920
US Classification:
435198, 4352523, 4353201, 536 232, 530350
Abstract:
The present invention relates to isolated polypeptides having lysophospholipase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.

Aspartic Proteinase Deficient Filamentous Fungi

View page
US Patent:
6509171, Jan 21, 2003
Filed:
Mar 26, 1998
Appl. No.:
09/048473
Inventors:
Randy M. Berka - Davis CA
Kirk J. Hayenga - Raleigh NC
Virgil B. Lawlis - Raleigh NC
Michael Ward - San Francisco CA
Assignee:
Genencor International, Inc. - Palo Alto CA
International Classification:
C12P 2102
US Classification:
435 691, 435 694, 435 6951, 435 696, 435202, 435205, 435212
Abstract:
This invention relates to novel mutant filamentous fungi which are deficient in the gene for the corresponding aspartic proteinase. These organisms are useful production hosts in the production of heterologous polypeptides such as chymosin.

Promoters For Expressing Genes In A Fungal Cell

View page
US Patent:
6518044, Feb 11, 2003
Filed:
Oct 30, 2001
Appl. No.:
09/999201
Inventors:
Randy M. Berka - Davis CA
Michael W. Rey - Davis CA
Kimberly Brown - Elk Grove CA
Stephen H. Brown - Davis CA
Assignee:
Novozymes Biotech, Inc. - Davis CA
International Classification:
C12P 2102
US Classification:
435 691, 536 241
Abstract:
The present invention relates to methods for producing a polypeptide, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first nucleic acid sequence encoding the polypeptide operably linked to a second nucleic acid sequence comprising a promoter foreign to the nucleic acid sequence, wherein the promoter comprises a sequence selected from the group consisting of nucleotides 1 to 3949 of SEQ ID NO:1, nucleotides 1 to 938 of SEQ ID NO:2, and nucleotides 1 to 3060 of SEQ ID NO:3, and a subsequence thereof; and mutant, hybrid, and tandem promoters thereof; and (b) isolating the polypeptide from the cultivation medium. The present invention also relates to the isolated promoter sequences and to constructs, vectors, and fungal host cells comprising the promoter sequences operably linked to nucleic acid sequences encoding polypeptides.

Nucleic Acid Sequences Encoding Cell Wall-Degrading Enzymes And Use To Engineer Resistance To Fusarium And Other Pathogens

View page
US Patent:
6521435, Feb 18, 2003
Filed:
Aug 28, 2000
Appl. No.:
09/649747
Inventors:
Patricia A. Okubara - Richmond CA
Ann E. Blechl - Albany CA
Thomas M. Hohn - Chapel Hill NC
Randy M. Berka - Davis CA
Assignee:
The United States of America as represented by the Secretary of Agriculture - Washington DC
Novozymes Biotech, Inc. - Davis CA
International Classification:
C12N 900
US Classification:
435206, 435183, 435200, 4352523, 4353201, 435419, 435468, 435 691, 536 232, 800295, 800298, 8003203
Abstract:
The invention is directed to nucleic acid sequences derived from Fusarium fungal genes which encode the cell wall-degrading enzymes glucanase, endochitinase, and exochitinase; isolated polypeptides having glucanase, endochitinase or exochitinase activity; recombinant nucleic acid molecules, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides, including expression in plant cells to confer or enhance a plants resistance to Fusarium and other pathogens.

Polypeptides Having Acid Phosphatase Activity And Nucleic Acids Encoding Same

View page
US Patent:
6667169, Dec 23, 2003
Filed:
Sep 19, 2001
Appl. No.:
09/957156
Inventors:
Debbie S. Yaver - Davis CA
Randy M. Berka - Davis CA
Michael W. Rey - Davis CA
Assignee:
Novozymes Biotech, Inc. - Davis CA
International Classification:
C12N 916
US Classification:
435196, 4352523, 43525233, 43525411, 4352542, 4353201, 435325, 435 691, 435 697, 435410, 536 232, 536 234, 536 237
Abstract:
The present invention relates to isolated polypeptides having acid phosphatase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.

Isbn (Books And Publications)

Applied Mycology and Biotechnology: Genes And Genomics

View page
Author

Randy M. Berka

ISBN #

0444518088

Molecular Industrial Mycology: Systems and Applications for Filamentous Fungi

View page
Author

Randy M. Berka

ISBN #

0824783921

Randy M Berka from Woodland, CA, age ~70 Get Report