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Ramzey J Abujarour

from San Diego, CA
Age ~51

Ramzey Abujarour Phones & Addresses

  • 13281 Deron Ave, San Diego, CA 92129
  • 2200 Waterview Pl, Richardson, TX 75080 (972) 644-2611
  • 2600 Waterview Pl, Richardson, TX 75080 (972) 644-2611
  • Solana Beach, CA

Resumes

Resumes

Ramzey Abujarour Photo 1

Director, Reprogramming And Cellular Engineering

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Location:
San Diego, CA
Industry:
Biotechnology
Work:
Fate Therapeutics Inc
Director, Reprogramming and Cellular Engineering

The Scripps Research Institute Apr 2005 - Dec 2009
Postdoctoral Research Associate

Gnf May 2006 - Dec 2007
Postdoctoral Scientist
Education:
The University of Texas at Dallas 2000 - 2005
Doctorates, Doctor of Philosophy, Biology
Westminster Business School 1996 - 1997
Master of Science, Masters, Molecular Biology
University of Jordan 1992 - 1996
Bachelors, Bachelor of Science, Biology
Skills:
Molecular Biology
Cell Culture
Stem Cells
Cell
Drug Discovery
Cell Biology
Assay Development
Life Sciences
Biotechnology
Western Blotting
High Throughput Screening
Tissue Culture
Biochemistry
In Vitro
Qpcr
Genetics
Pcr
Elisa
Molecular Cloning
Facs
Immunohistochemistry
In Vivo
Transfection
Antibodies
Rt Pcr
Lifesciences
Cancer Research
Immunology
Ramzey Abujarour Photo 2

Ramzey Abujarour

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Publications

Us Patents

Reprogramming Methods And Cell Culture Platforms

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US Patent:
20220228125, Jul 21, 2022
Filed:
Jan 19, 2022
Appl. No.:
17/579169
Inventors:
- San Diego CA, US
Peter FLYNN - San Diego CA, US
Ramzey ABUJAROUR - San Diego CA, US
Megan ROBINSON - San Diego CA, US
International Classification:
C12N 5/074
C12N 5/073
C12N 15/86
Abstract:
The invention provides compositions and methods for manufacturing pluripotent cells. In particular, the invention provides improved culture platforms for manufacturing pluripotent cells with ground state pluripotency. In various embodiments, the invention contemplates, in part, a composition comprising: (a) a Wnt pathway agonist; (b) a MEK inhibitor; and (c) a ROCK inhibitor. In certain embodiments, the composition further comprises bFGF or LIF.

Genomic Engineering Of Pluripotent Cells

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US Patent:
20210324340, Oct 21, 2021
Filed:
Apr 22, 2021
Appl. No.:
17/237897
Inventors:
- San Diego CA, US
Ramzey ABUJAROUR - San Diego CA, US
Tom Tong LEE - San Diego CA, US
Weijie LAN - San Diego CA, US
Raedun CLARKE - San Diego CA, US
Ryan BJORDAHL - San Diego CA, US
International Classification:
C12N 5/074
C12N 15/90
C12N 5/0783
A61P 35/02
C07K 16/28
A61P 35/00
C12N 5/078
C12N 15/85
A61K 35/17
C07K 14/705
C07K 14/725
C12N 9/22
C12N 15/11
Abstract:
Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites. Also provided are cell populations or clonal cell lines derived from genome-engineered iPSCs, which comprise targeted integration of one or more exogenous polynucleotides, and/or in/dels in one or more selected endogenous genes.

Cell Culture Platform For Single Cell Sorting And Enhanced Reprogramming Of Ipscs

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US Patent:
20210079359, Mar 18, 2021
Filed:
Sep 30, 2020
Appl. No.:
17/039006
Inventors:
- San Diego CA, US
Ramzey Abujarour - San Diego CA, US
Peter Flynn - San Diego CA, US
International Classification:
C12N 5/074
Abstract:
The invention provides cell culture conditions for culturing stem cells, including feeder-free conditions for generating and culturing human induced pluripotent stem cells (iPSCs). More particularly, the invention provides a culture platform that allows long-term culture of pluripotent cells in a feeder-free environment; reprogramming of cells in a feeder-free environment; single-cell dissociation of pluripotent cells; cell sorting of pluripotent cells; maintenance of an undifferentiated status; improved efficiency of reprogramming; and generation of a naïve pluripotent cell.

Genomic Engineering Of Pluripotent Cells

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US Patent:
20200095604, Mar 26, 2020
Filed:
Oct 17, 2019
Appl. No.:
16/656484
Inventors:
- San Diego CA, US
Ramzey ABUJAROUR - San Diego CA, US
Tom Tong LEE - San Diego CA, US
Weijie LAN - San Diego CA, US
Raedun CLARKE - San Diego CA, US
Ryan BJORDAHL - San Diego CA, US
International Classification:
C12N 15/85
C12N 5/078
A61P 35/00
C07K 16/28
A61P 35/02
C12N 5/0783
C12N 15/11
C12N 9/22
C07K 14/725
C07K 14/705
A61K 35/17
C12N 15/90
C12N 15/113
C12N 5/074
Abstract:
Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites. Also provided are cell populations or clonal cell lines derived from genome-engineered iPSCs, which comprise targeted integration of one or more exogenous polynucleotides, and/or in/dels in one or more selected endogenous genes.

Genomic Engineering Of Pluripotent Cells

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US Patent:
20190271005, Sep 5, 2019
Filed:
Apr 9, 2019
Appl. No.:
16/379668
Inventors:
- San Diego CA, US
Ramzey Abujarour - San Diego CA, US
Tom Tong Lee - San Diego CA, US
Weijie Lan - San Diego CA, US
Raedun Clarke - San Diego CA, US
Ryan Bjordahl - San Diego CA, US
International Classification:
C12N 15/85
A61K 35/17
C12N 5/074
C12N 9/22
C07K 14/705
C12N 15/11
C07K 14/725
C12N 15/113
C12N 15/90
Abstract:
Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites. Also provided are cell populations or clonal cell lines derived from genome-engineered iPSCs, which comprise targeted integration of one or more exogenous polynucleotides, and/or in/dels in one or more selected endogenous genes.

Platform For The Induction & Maintenance Of Ground State Pluripotency

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US Patent:
20190218520, Jul 18, 2019
Filed:
Oct 14, 2016
Appl. No.:
15/767980
Inventors:
- San Diego CA, US
Megan Robinson - San Diego CA, US
Ramzey Abujarour - San Diego CA, US
International Classification:
C12N 5/074
C12N 15/86
C12N 15/113
Abstract:
The invention provides compositions and methods for manufacturing pluripotent cells. In particular, the invention provides improved culture platforms for manufacturing pluripotent cells with ground state pluripotency.

Genomic Engineering Of Pluripotent Cells

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US Patent:
20180155717, Jun 7, 2018
Filed:
Nov 20, 2017
Appl. No.:
15/818649
Inventors:
- San Diego CA, US
Ramzey Abujarour - San Diego CA, US
Tom Tong Lee - San Diego CA, US
Weijie Lan - San Diego CA, US
Raedun Clarke - San Diego CA, US
Ryan Bjordahl - San Diego CA, US
International Classification:
C12N 15/11
A61K 35/17
C12N 5/074
C07K 14/705
C07K 14/725
C12N 9/22
C12N 15/85
Abstract:
Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites. Also provided are cell populations or clonal cell lines derived from genome-engineered iPSCs, which comprise targeted integration of one or more exogenous polynucleotides, and/or in/dels in one or more selected endogenous genes.

Cell Culture Platform For Single Cell Sorting And Enhanced Reprogramming Of Ipscs

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US Patent:
20170362569, Dec 21, 2017
Filed:
Jun 30, 2017
Appl. No.:
15/639628
Inventors:
- San Diego CA, US
Ramzey Abujarour - San Diego CA, US
Peter Flynn - San Diego CA, US
International Classification:
C12N 5/074
Abstract:
The invention provides cell culture conditions for culturing stem cells, including feeder-free conditions for generating and culturing human induced pluripotent stem cells (iPSCs). More particularly, the invention provides a culture platform that allows long-term culture of pluripotent cells in a feeder-free environment; reprogramming of cells in a feeder-free environment; single-cell dissociation of pluripotent cells; cell sorting of pluripotent cells; maintenance of an undifferentiated status; improved efficiency of reprogramming; and generation of a naïve pluripotent cell.
Ramzey J Abujarour from San Diego, CA, age ~51 Get Report