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Rainer K Brachmann

from Truckee, CA
Age ~63
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Also known as:
Rainer Karl Brachmann, Rainer Carrie Brachmann, Rainer Carrie Brachman, Rainer K Brachman, Brachmann Rainer
Related to:
Carrie B Brachmann, 59William C Baker, 85Thad W Baker, 54Linda L Baker, 82Esme Brachmann, 27
Connected to:
Thomas A Brachmann, 66Tina Brachman, 50Cora B Bracho, 64Edward J Brachocki, 68Evanan R Bracho, 55Felipe R Bracho, 54Gabriela C Bracho, 30Joel C Bracho, 49Marcelo L Bracho, 63Marcos J Bracho, 48

Rainer Brachmann Phones & Addresses

  • Truckee, CA
  • Fullerton, CA
  • 716 Concord Way, Burlingame, CA 94010 (650) 931-4300
  • 2965 Alpine Way, Laguna Beach, CA 92651
  • 7322 Cornell Ave, Saint Louis, MO 63130
  • University City, MO
  • Baltimore, MD
  • Silver Spring, MD
  • San Mateo, CA
  • Orange, CA
  • 716 Concord Way, Burlingame, CA 94010

Work

Company: UC Irvine Health Address: 101 The City Drive South, Orange, CA 92868

Education

School / High School: Ludwig-Maximilians-Universitaet Munchen, Fachbereich Medizin 1987

Languages

English

Awards

Healthgrades Honor Roll

Ranks

Certificate: Internal Medicine, 1993

Specialities

Oncology • Medical Oncology

Professional Records

Medicine Doctors

Rainer Brachmann Photo 1

Dr. Rainer Brachmann, Orange CA - MD (Doctor of Medicine)

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Specialties:
Oncology
Medical Oncology
Address:
101 The City Dr S, Orange, CA 92868
Certifications:
Internal Medicine, 1993
Medical Oncology, 1995
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
101 The City Dr S, Orange, CA 92868

UC Irvine Health
101 The City Drive South, Orange, CA 92868
Education:
Medical School
Ludwig-Maximilians-Universitaet Munchen, Fachbereich Medizin
Graduated: 1987
Rainer Brachmann Photo 2

Rainer Karl Brachmann, Orange CA

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Specialties:
Medical Oncology
Hematology & Oncology
Work:
Uci Medical Center
101 The City Dr S, Orange, CA 92868
Education:
Ludwig-Maximilians-Universitaet Munchen (1987)
Rainer Brachmann Photo 3

Rainer Brachmann, Orange CA

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Specialties:
Internist
Address:
101 The City Dr S, Orange, CA 92868
Education:
Doctor of Medicine
Board certifications:
American Board of Internal Medicine Sub-certificate in Oncology (Internal Medicine)

Business Records

Name / Title
Company / Classification
Phones & Addresses
Rainer Karl Brachmann
Rainer Brachmann MD
Internist
101 The City Dr S, Orange, CA 92868
(714) 456-8978

Publications

Us Patents

Global Suppressors Of P53 Mutations

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US Patent:
20050065332, Mar 24, 2005
Filed:
Jan 15, 2003
Appl. No.:
10/500155
Inventors:
Rainer Brachmann - Laguna Beach CA, US
Assignee:
Washington University - St. Louis MO
International Classification:
C07H021/04
C12N009/02
US Classification:
536023200, 435069100, 435189000, 435320100, 435325000
Abstract:
The transcription factor and tumor suppressor protein p53 is inactivated in many human cancers. Approximately forty percent of cancers carry large amounts of mutated full-length p53 protein with one of over 900 reported single amino acid changes in the p53 core domain that recognizes p53 DNA binding sites. The ability to restore function to these inactive p53 proteins would dramatically improve cancer therapy. We show that this goal is achievable. Using genetic strategies and p53 assays in the yeast and mammalian cells, we identify suppressor mutations that, in the context of the some protein, restore function to some of the most common p53 cancer mutants tested. Crystallographic studies of this general suppressor motif eludicate the structural basis of restoring integrity to the p53 core domain and lead to small compounds that stabilize p53 cancer mutants.

Maintenance Therapy Of A Parp Inhibitor In Treating Gastric Cancer

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US Patent:
20210205323, Jul 8, 2021
Filed:
May 31, 2019
Appl. No.:
17/058812
Inventors:
- Camana Bay, Grand Cayman, KY
Rainer K. BRACHMANN - Emeryville CA, US
Yuting ZHANG - Emeryville CA, US
Mitch RAPONI - Emeryville CA, US
Heinrich FARIN - Cambridge MA, US
Lai WANG - Beijing, CN
Hexiang WANG - Beijing, CN
International Classification:
A61K 31/551
A61K 33/243
A61K 31/555
A61P 35/00
Abstract:
Disclosed herein is a method for maintenance therapy of a PARP inhibitor in treating a subject with gastric cancer (GC) comprising administering to the subject a therapeutic or maintenance effective amount of a PARP inhibitor, wherein the subject had previously received chemotherapy.
Control profile
Rainer K Brachmann from Truckee, CA, age ~63 Get Report