US Patent:
20200231541, Jul 23, 2020
Inventors:
- Morrisville NC, US
Qibo Zhang - Cary NC, US
International Classification:
C07C 323/54
C07K 16/44
C07C 319/18
G01N 30/72
Abstract:
The present invention provides a compound of formula (I), formula (II), formula (III), (IV) or a salt thereof, compositions and methods of making the compound, methods and reagents for measuring the compound, and kits using the same. The use of a compound of formula (I), formula (II), formula (III), or formula (IV) for assessing or monitoring kidney function in a subject, determining predisposition to developing reduced kidney function, classifying a subject according to level of kidney function, and diagnosing or monitoring chronic kidney disease is also described.