Search

Qibo Zhang Phones & Addresses

  • 607 Ivyshaw Rd, Cary, NC 27519
  • 6211 Johnston Rd, Albany, NY 12203 (518) 456-4933
  • 500 Wilke Rd, Palatine, IL 60074 (847) 222-0414
  • 212 6Th St, Coralville, IA 52241 (319) 351-2169
  • 2333 Priscilla St, Saint Paul, MN 55108 (651) 649-1475
  • Corvallis, OR
  • Wade, NC

Publications

Us Patents

Novel Macrocyclic Polyene Lactams

View page
US Patent:
20090149395, Jun 11, 2009
Filed:
Dec 10, 2008
Appl. No.:
12/331594
Inventors:
Aaron PEOPLES - Cambridge MA, US
Qibo ZHANG - Albany NY, US
Charles MOORE - Boston MA, US
Kim LEWIS - Newton MA, US
International Classification:
A61K 31/70
C07D 225/02
C12N 1/20
A61K 31/395
US Classification:
514 23, 540463, 536 187, 514183, 514459, 4352521
Abstract:
The invention relates generally to novel macrocyclic polyene lactams and their analogs, to processes for the preparation of these novel macrocyclic polyene lactams, to pharmaceutical compositions comprising the novel macrocyclic polyene lactams; and to methods of using the novel macrocyclic polyene lactams to treat or inhibit various disorders.

Novel Macrolactam Compounds

View page
US Patent:
20090156514, Jun 18, 2009
Filed:
Aug 22, 2008
Appl. No.:
12/196714
Inventors:
Aaron PEOPLES - Cambridge MA, US
Qibo ZHANG - Albany NY, US
Charles MOORE - Boston MA, US
Losee Lucy LING - Arlington MA, US
Mithra ROTHFEDER - , US
Kim Lewis - Newton MA, US
Assignee:
NovoBiotic Pharmaceuticals LLC - Cambridge MA
International Classification:
A61K 31/7052
C07H 17/02
C12N 1/20
US Classification:
514 31, 536 174, 4352521
Abstract:
The invention relates generally to novel macrolactams and their analogs, to processes for the preparation of these novel macrolactams, to pharmaceutical compositions comprising the novel macrolactams; and to methods of using the novel macrolactams to treat or inhibit various disorders.

Compounds, Reagents, And Uses Thereof

View page
US Patent:
20200231541, Jul 23, 2020
Filed:
Sep 27, 2018
Appl. No.:
16/650429
Inventors:
- Morrisville NC, US
Qibo Zhang - Cary NC, US
International Classification:
C07C 323/54
C07K 16/44
C07C 319/18
G01N 30/72
Abstract:
The present invention provides a compound of formula (I), formula (II), formula (III), (IV) or a salt thereof, compositions and methods of making the compound, methods and reagents for measuring the compound, and kits using the same. The use of a compound of formula (I), formula (II), formula (III), or formula (IV) for assessing or monitoring kidney function in a subject, determining predisposition to developing reduced kidney function, classifying a subject according to level of kidney function, and diagnosing or monitoring chronic kidney disease is also described.

Mass Spectrometry Method For Detection And Quantitation Of Metabolites

View page
US Patent:
20200166519, May 28, 2020
Filed:
May 26, 2017
Appl. No.:
16/305078
Inventors:
- Morrisville NC, US
Qibo ZHANG - Cary NC, US
Klaus Peter ADAM - Cary NC, US
International Classification:
G01N 33/68
G01N 30/72
Abstract:
A method for determining the amount of one or more analytes in a sample by mass spectrometry is described. The one or more analytes are selected from the group consisting of alpha-hydroxybutyrate (2-HB), linoleoyl LPC (LGPC), oleic acid, 3-hydroxybutyrate (3-HB), 4-methyl-2-oxopentanoate (4-MOP), pantothenate, and serine. The method includes a) subjecting the sample to an ionization source under conditions suitable to produce one or more ions detectable by mass spectrometry from each of the one or more of the analytes, wherein the analytes are not derivatized prior to ionization; b) measuring, by tandem mass spectrometry, the amount of the one or more ions from each of the one or more analytes; and c) using the measured amount of the one or more ions to determine the amount of each of the one or more analytes in the sample.

Diagnostic Methods, Therapeutic Agents And Uses Thereof

View page
US Patent:
20200110069, Apr 9, 2020
Filed:
Oct 14, 2019
Appl. No.:
16/601198
Inventors:
- Morrisville NC, US
Klaus Peter Adam - Cary NC, US
Michael V. Milburn - Cary NC, US
Jeffery E. Cobb - Chapel Hill NC, US
Anne M. Evans - Cary NC, US
Qibo Zhang - Cary NC, US
International Classification:
G01N 33/50
C07K 16/44
C07D 307/33
A61K 31/341
A61K 31/137
A61K 31/7048
A61K 31/4439
A61K 31/155
A61K 31/485
G01N 33/68
Abstract:
The present invention provides a method for diagnosing a disease or disorder selected from the group consisting of insulin resistance, a metabolic disorder, diabetes and pre-diabetes in a subject. The method comprises the step of determining the level of a compound represented by structural formula (VI):or a salt thereof. Compositions and method of making thereof are also described.

Diagnostic Methods, Therapeutic Agents And Uses Thereof

View page
US Patent:
20180031541, Feb 1, 2018
Filed:
Feb 4, 2016
Appl. No.:
15/548854
Inventors:
- Morrisville NC, US
Klaus Peter Adam - Cary NC, US
Michael V. Milburn - Cary NC, US
Jeffery E. Cobb - Chapel Hill NC, US
Anne M. Evans - Cary NC, US
Qibo Zhang - Cary NC, US
International Classification:
G01N 33/50
C07K 16/44
C07D 307/33
Abstract:
The present invention provides a method for diagnosing a disease or disorder selected from the group consisting of insulin resistance, a metabolic disorder, diabetes and pre-diabetes in a subject. The method comprises the step of determining the level of a compound represented by structural formula (VI): or a salt thereof. Compositions and method of making thereof are also described.
Qibo Zhang from Cary, NC, age ~59 Get Report