Pingchen A Fan

6809104, Oct 26, 2004

Nov 6, 2002

10/289933

Xiaoqi Chen - San Mateo CA
Pingchen Fan - Fremont CA
Juan Jaen - Burlingame CA
Leping Li - Burlingame CA
Mike Lizarzaburu - San Bruno CA
Jeffrey Thomas Mihalic - San Francisco CA
Stephen Joseph Shuttleworth - Foster City CA

Tularik Inc. - South San Francisco CA

C07D47104

514285, 546 70

Compounds having the formula: wherein L is a bond or (C -C )alkylene, Râ is hydrogen or (C -C )alkyl, and R , R , R , R, Râ, and the subscript n are as described herein, are provided, which are useful in the treatment and/or prevention of a condition or disorder mediated by a G-protein coupled receptor. Pharmaceutical compositions and methods of using these compounds for the treatment and/or prevention of a condition or disorder mediated by a G-protein coupled receptor, such as eating disorders, obesity, anxiety disorders and mood disorders, are also provided.

6858619, Feb 22, 2005

May 3, 2002

10/138279

Xiaoqi Chen - San Mateo CA, US
Kang Dai - Albany CA, US
Pingchen Fan - Fremont CA, US
Shugui Huang - San Bruno CA, US
Leping Li - Burlingame CA, US
Jeffrey Thomas Mihalic - San Francisco CA, US

Amgen Inc. - Thousand Oaks CA

C07D471/04
A61K031/437
A61P003/04
A61P025/22

514285, 549 70

Compounds useful in the treatment and/or prevention of a condition or disorder mediated by a G-protein coupled receptor are provided that have the formula: wherein.

7045527, May 16, 2006

Sep 23, 2003

10/669606

Xiaoqi Chen - San Mateo CA, US
Kang Dai - Albany CA, US
Pingchen Fan - Fremont CA, US
Ying Fu - Menlo Park CA, US
Leping Li - Burlingame CA, US
Jeffrey T. Mihalic - San Francisco CA, US

Amgen Inc. - South San Francisco CA

A61K 31/438
C07D 401/06
C07D 401/14

514278, 546 18

Compounds, compositions and methods are provided that are useful in the treatment or prevention of conditions or disorders associated with a neuropeptide receptor. The subject methods are particularly useful in the treatment and/or prevention of endocrine, metabolic, cardiovascular, neurologic, psychiatric, gastrointestinal, genitourinary and other disorders.

7053234, May 30, 2006

Jun 25, 2004

10/877408

Leping Li - Burlingame CA, US
Xiaoqi Chen - San Mateo CA, US
Pingchen Fan - Newark CA, US
Jeffrey Thomas Mihalic - San Francisco CA, US
Serena Cutler - Palo Alto CA, US

Amgen Inc. - Thousand Oaks CA

C07C 275/28

558 8

Hydroxyamidines and related compounds are provided which are suitable as antibacterial agents.

7125885, Oct 24, 2006

Aug 26, 2004

10/928029

Xiaoqi Chen - San Mateo CA, US
Pingchen Fan - Fremont CA, US
Juan Jaen - Burlingame CA, US
Leping Li - Burlingame CA, US
Mike Lizarzaburu - San Bruno CA, US
Jeffrey Thomas Mihalic - San Francisco CA, US
Stephen Joseph Shuttleworth - Foster City CA, US

Amgen Inc. - Thousand Oaks CA

C07D 471/04
A61K 31/437

514285, 546 70

The present invention provides compounds having the formula:.

7148259, Dec 12, 2006

Feb 1, 2006

11/344111

Leping Li - Burlingame CA, US
Xiaoqi Chen - San Mateo CA, US
Pingchen Fan - Newark CA, US
Jeffrey Thomas Mihalic - San Francisco CA, US
Serena Cutler - Palo Alto CA, US

Amgen Inc. - Thousand Oaks CA

A61K 31/04

514742

Hydroxyamidines and related compounds are provided which are suitable as antibacterial agents.

7253179, Aug 7, 2007

Nov 6, 2003

10/705173

Xi Chen - Palo Alto CA, US
Xiaoqi Chen - San Mateo CA, US
Pingchen Fan - Fremont CA, US
Juan Jaen - Burlingame CA, US
Leping Li - Burlingame CA, US
Jeffrey Thomas Mihalic - San Francisco CA, US

Amgen Inc. - Thousand Oaks CA

A61K 31/4745
C07D 471/02

514285, 546 70

Compounds, compositions and methods are provided that are useful in the treatment and/or prevention of a condition or disorder mediated by a G-protein coupled receptor. In particular, the compounds of the invention are useful in the treatment and/or prevention of eating disorders, obesity, anxiety disorders and mood disorders.

7402704, Jul 22, 2008

Apr 14, 2005

11/105583

Pingchen Fan - Fremont CA, US
Hiroyuki Goto - Takatsuki, JP
Xiao He - Foster City CA, US
Makoto Kakutani - Takatsuki, JP
Marc Labelle - Chatham NJ, US
Dustin L. McMinn - Pacifica CA, US
Jay P. Powers - Pacifica CA, US
Yosup Rew - Foster City CA, US
Daqing Sun - Foster City CA, US
Xuelei Yan - Burlingame CA, US

Amgen Inc. - Thousand Oaks CA

C07C 317/14
A61K 31/255
A61K 31/275

568 28, 568 34, 558413, 514518, 514520

Aryl sulfone compounds of formula I and II are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders:.