Ping Ping Jiang from San Diego, CA, age 32

Professional Records

Medicine Doctors

Ping Ping Jiang

View page

Specialties:

Internal Medicine
Cardiovascular Disease
Interventional Cardiology
Cardiology

Education:

Yale University (1990)

Publications

Us Patents

Real Time Measurement Of Cellular Responses

View page

US Patent:

6905831, Jun 14, 2005

Filed:

Aug 18, 2003

Appl. No.:

10/643785

Inventors:

Ping Jiang - San Diego CA, US
Mingxu Xu - La Jolla CA, US
Meng Yang - San Diego CA, US

Assignee:

Anticancer, Inc. - San Diego CA

International Classification:

C12Q001/68

US Classification:

435 6, 435455, 435366

Abstract:

Living cells can be stably modified to emit different colors from the cytoplasm and nucleus, thus permitting analysis of the status of said cells and the effect of agents on said cells either by visual or instrumentally-aided observation. These observations may be made, if desired, in real time. In addition, rates of proliferation and drug sensitivities can be determined in vitro in real time by the use of cells modified to express a single fluorescent protein and observing fluorescence intensity as a function of time.

Expression Profiling Based On Histocultures

View page

US Patent:

7252941, Aug 7, 2007

Filed:

Nov 12, 2003

Appl. No.:

10/712781

Inventors:

Ping Jiang - San Diego CA, US
Mingxu Xu - La Jolla CA, US
Yuying Tan - San Diego CA, US

Assignee:

AntiCancer, Inc. - San Diego CA

International Classification:

C12Q 1/68

US Classification:

435 6, 435 9151, 435378

Abstract:

Methods of obtaining faithful expression libraries from tissue samples comprise extraction of RNA from intact tissue cultured in three-dimensional sponge-gel based histocultures.

Immunocompromised Rodents As Dual Color Tumor Models

View page

US Patent:

8148600, Apr 3, 2012

Filed:

Feb 9, 2004

Appl. No.:

10/775554

Inventors:

Meng Yang - San Diego CA, US
Eligio Reynoso - San Diego CA, US
Mingxu Xu - San Diego CA, US
Ping Jiang - San Diego CA, US

Assignee:

Anticancer, Inc. - San Diego CA

International Classification:

A01K 67/027
A01K 67/02

US Classification:

800 18, 800 13, 800 22

Abstract:

Immunocompromised rodents that have been modified to express a fluorescent protein in substantially all tissues are described. These rodents are useful as models for gene expression, tumor progression and angiogenesis. Also provided are model systems where heterologous tissues fluorescing in a first color are transplanted into hosts that have been modified to fluoresce in substantially all tissues with a second color.

Fluorescent Proteins

View page

US Patent:

20020132318, Sep 19, 2002

Filed:

Jan 29, 2002

Appl. No.:

10/060857

Inventors:

Ming Zhao - San Diego CA, US
Mingxu Xu - La Jolla CA, US
Ping Jiang - San Diego CA, US
Meng Yang - San Diego CA, US

International Classification:

C12N009/00
C07H021/04
C07K014/435
C12N005/06
C12P021/02

US Classification:

435/183000, 435/069100, 435/320100, 435/325000, 530/350000, 536/023200

Abstract:

Improved forms of fluorescent protein with high fluorescence and low toxicity are disclosed.

System For Monitoring Bacterial Tumor Treatment

View page

US Patent:

20030161788, Aug 28, 2003

Filed:

Dec 31, 2002

Appl. No.:

10/335056

Inventors:

Ming Zhao - San Diego CA, US
Xiao-Ming Li - San Diego CA, US
Meng Yang - San Diego CA, US
Mingxu Xu - La Jolla CA, US
Ping Jiang - San Diego CA, US
Lingna Li - San Diego CA, US

International Classification:

A61K048/00
A61K049/00

US Classification:

424/009600, 424/093210

Abstract:

A method to follow the progress of tumor treatment in subjects utilizes bacteria that have been modified to express a fluorescent protein. The method can also monitor expression of genes associated with the bacteria that produce therapeutic agents during the course of treatment, optionally against a background of fluorescence generated by the tumor itself. The method permits visualization of the progress of treatment in live subjects so that treatments can be modified according to their efficacy.

Fluorescence Guided Cell Capture

View page

US Patent:

20040224370, Nov 11, 2004

Filed:

Nov 12, 2003

Appl. No.:

10/712782

Inventors:

Ping Jiang - San Diego CA, US
Meng Yang - San Diego CA, US
Mingxu Xu - La Jolla CA, US

International Classification:

C12Q001/68
G01N033/574
C07K014/435

US Classification:

435/007230, 435/325000, 530/350000

Abstract:

Methods of recovering desired living cells contained in a tissue sample are based on separation based on fluorescence of a fluorescent protein produced by the desired cells.

Angiogensis Models Using Nestin-Expressing Stem Cells To Image Nascent Blood Vessels

View page

US Patent:

20050170330, Aug 4, 2005

Filed:

Oct 28, 2004

Appl. No.:

10/977219

Inventors:

Yasuyuki Amoh - San Diego CA, US
Lingna Li - San Diego CA, US
Meng Yang - San Diego CA, US
Ping Jiang - San Diego CA, US

Assignee:

AntiCancer, Inc. - San Diego CA

International Classification:

C12Q001/00
A01K067/027

US Classification:

435004000, 435325000, 800019000

Abstract:

The disclosed invention relates to the observation that nestin expression is a marker for endothelial cell proliferation. Nestin expression is particularly useful as a marker for angiogenesis, particularly for tumor-related angiogenesis. Specifically, nestin serves as an excellent endothelium marker for brain tumors such as gliomas, hemangioblastomas, Schwannomas, medulloblastomas, and meningiomas. Accordingly, the disclosed invention relates to the use of this marker as a basis to model angiogenic activity.