Inventors:
- Dallas TX, US
Pia D. Vogel - Dallas TX, US
Frances K. Brewer - Waxahachie TX, US
Courtney A. Follit - Dallas TX, US
Amila K. Nanyakkara - Dallas TX, US
Alexander R. Lippert - Dallas TX, US
Maha Ali Aljowni - Tabuk, SA
International Classification:
A61K 31/5025
A61K 31/353
A61K 31/4196
A61K 31/4525
A61K 45/06
A61K 31/352
Abstract:
The present disclosure provides a method of treating a subject that is resistant to one or more drugs by identifying a subject having one or more drug resistant cells; administering to the subject a pharmaceutically effective amount of an inhibitor compound, and contacting one or more drug resistant cells with the inhibitor compound to reduce the export of the inhibitor compound from the one or more drug resistant tumor cells and to block the transport of drug(s) from the one or more drug resistant cells.