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Philip D Laible

from Downers Grove, IL
Age ~57

Philip Laible Phones & Addresses

  • 727 Millbrook Dr, Downers Grove, IL 60516
  • 117 Yale Ave, Villa Park, IL 60181 (630) 279-1418
  • Lemont, IL
  • Dryden, NY
  • Urbana, IL
  • Newfield, NY
  • 117 N Yale Ave, Villa Park, IL 60181 (630) 336-2027

Work

Position: Food Preparation and Serving Related Occupations

Publications

Us Patents

Biomimetic Materials For Protein Storage And Transport

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US Patent:
8168746, May 1, 2012
Filed:
Apr 18, 2008
Appl. No.:
12/148518
Inventors:
Millicent A. Firestone - Elmhurst IL, US
Philip D. Laible - Villa Park IL, US
Assignee:
UChicago Argonne, LLC - Chicago IL
International Classification:
C07K 14/00
US Classification:
530300, 514 2
Abstract:
The invention provides a method for the insertion of protein in storage vehicles and the recovery of the proteins from the vehicles, the method comprising supplying isolated protein; mixing the isolated protein with a fluid so as to form a mixture, the fluid comprising saturated phospholipids, lipopolymers, and a surfactant; cycling the mixture between a first temperature and a second temperature; maintaining the mixture as a solid for an indefinite period of time; diluting the mixture in detergent buffer so as to disrupt the composition of the mixture, and diluting to disrupt the fluid in its low viscosity state for removal of the guest molecules by, for example, dialysis, filtering or chromatography dialyzing/filtering the emulsified solid.

Amphiphiles For Protein Solubilization And Stabilization

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US Patent:
8263754, Sep 11, 2012
Filed:
Apr 8, 2009
Appl. No.:
12/420701
Inventors:
Samuel Helmer Gellman - Madison WI, US
Pil Seok Chae - Madison WI, US
Philip D. Laible - Villa Park IL, US
Marc J. Wander - Downers Grove IL, US
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
UChicago Argonne, LLC - Chicago IL
International Classification:
C07H 15/00
A61K 31/7028
US Classification:
536 179, 536 172, 536 41, 514 25, 530409
Abstract:
The invention provides amphiphiles for manipulating membrane proteins. The amphiphiles can feature carbohydrate-derived hydrophilic groups and branchpoints in the hydrophilic moiety and/or in a lipophilic moiety. Such amphiphiles are useful as detergents for solubilization and stabilization of membrane proteins, including photosynthetic protein superassemblies obtained from bacterial membranes.

Cell-Free System For Synthesizing Membrane Proteins Cell Free Method For Synthesizing Membrane Proteins

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US Patent:
8455231, Jun 4, 2013
Filed:
Feb 8, 2010
Appl. No.:
12/702167
Inventors:
Philip D. Laible - Villa Park IL, US
Deborah K. Hanson - Villa Park IL, US
Assignee:
Uchicago Argonne, LLC - Chicago IL
International Classification:
C12N 9/10
US Classification:
435193, 4351737, 4353071
Abstract:
The invention provides an in vitro method for producing proteins, membrane proteins, membrane-associated proteins, and soluble proteins that interact with membrane-associated proteins for assembly into an oligomeric complex or that require association with a membrane for proper folding. The method comprises, supplying intracytoplasmic membranes from organisms; modifying protein composition of intracytoplasmic membranes from organism by modifying DNA to delete genes encoding functions of the organism not associated with the formation of the intracytoplasmic membranes; generating appropriate DNA or RNA templates that encode the target protein; and mixing the intracytoplasmic membranes with the template and a transcription/translation-competent cellular extract to cause simultaneous production of the membrane proteins and encapsulation of the membrane proteins within the intracytoplasmic membranes.

Methods And Constructs For Expression Of Foreign Proteins In Photosynthetic Organisms

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US Patent:
20020102655, Aug 1, 2002
Filed:
Feb 1, 2001
Appl. No.:
09/775345
Inventors:
Philip Laible - Villa Park IL, US
Deborah Hanson - Downers Grove IL, US
International Classification:
C12P021/04
C07H021/04
US Classification:
435/069700, 435/320100, 536/023500
Abstract:
A method for expressing and purifying foreign proteins in photosynthetic organisms comprising the simultaneous expression of both the heterologous protein and a means for compartmentalizing or sequestering of the protein.

Versatile Vectors For Expression Of Foreign Proteins In Photosynthetic Bacteria

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US Patent:
20070092943, Apr 26, 2007
Filed:
Sep 28, 2006
Appl. No.:
11/536331
Inventors:
Philip Laible - Villa Park IL, US
Deborah Hanson - Villa Park IL, US
Assignee:
THE UNIVERSITY OF CHICAGO - Chicago IL
International Classification:
C12P 21/06
C07H 21/04
C12N 15/74
C12N 1/21
C07K 14/195
US Classification:
435069100, 435252300, 435471000, 530350000, 536023700
Abstract:
Methods for expressing and purifying foreign (heterologous) proteins in photosynthetic organisms employ expression of both heterologous membrane proteins and a means for compartmentalizing or sequestering of the protein.

Engineered Photosynthetic Bacteria, Method Of Manufacture Of Biofuels

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US Patent:
20110302830, Dec 15, 2011
Filed:
Jun 13, 2011
Appl. No.:
13/159340
Inventors:
Philip D. Laible - Villa Park IL, US
Seth W. Snyder - Lincolnwood IL, US
Assignee:
UCHICAGO ARGONNE, LLC - Chicago IL
International Classification:
C10L 1/182
C10L 1/16
C12P 7/04
C12P 1/00
C12P 5/00
US Classification:
44451, 435 41, 435166, 435157, 585 14
Abstract:
The invention provides for a novel type of biofuel; a method for cleaving anchors from photosynthetic organisms; and a method for producing biofuels using photosynthetic organisms, the method comprising identifying photosynthesis co-factors and their anchors in the organisms; modifying the organisms to increase production of the anchors; accumulating biomass of the organisms in growth media; and harvesting the anchors.

Transformable Rhodobacter Strains, Method For Producing Transformable Rhodobacter Strains

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US Patent:
20140080176, Mar 20, 2014
Filed:
Sep 14, 2012
Appl. No.:
13/619406
Inventors:
Philip D. Laible - Villa Park IL, US
Deborah K. Hanson - Villa Park IL, US
Assignee:
UCHICAGO ARGONNE, LLC - Chicago IL
International Classification:
C12N 1/21
C12P 21/00
C12P 1/04
C12N 15/74
C12M 1/42
US Classification:
435 691, 4352523, 435471, 4352852, 435170
Abstract:
The invention provides an organism for expressing foreign DNA, the organism engineered to accept standard DNA carriers. The genome of the organism codes for intracytoplasmic membranes and features an interruption in at least one of the genes coding for restriction enzymes. Further provided is a system for producing biological materials comprising: selecting a vehicle to carry DNA which codes for the biological materials; determining sites on the vehicle's DNA sequence susceptible to restriction enzyme cleavage; choosing an organism to accept the vehicle based on that organism not acting upon at least one of said vehicle's sites; engineering said vehicle to contain said DNA; thereby creating a synthetic vector; and causing the synthetic vector to enter the organism so as cause expression of said DNA.

Surfactant-Templated Synthesis Of Nanostructured Xerogel Adsorbent Platforms

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US Patent:
20200197900, Jun 25, 2020
Filed:
Dec 20, 2018
Appl. No.:
16/228593
Inventors:
- Chicago IL, US
Philip D. Laible - Downers Grove IL, US
Mackenzie Elizabeth Meyer - Ann Arbor MI, US
Christopher R. Povinelli - Milwaukee WI, US
Killian L. Tracey - Geneva IL, US
Daniel Yoav Arenas - Chicago IL, US
Assignee:
UCHICAGO ARGONNE, LLC - Chicago IL
International Classification:
B01J 20/10
C01B 33/16
B01J 20/28
B01J 20/24
B01J 20/22
B01J 20/30
B01J 20/32
C09K 3/32
Abstract:
A process for separations and recovery from mixtures via specific adsorption using high-surface area, flexible silica-based nanostructured gel adsorbents and articles of manufacture relating to same.
Philip D Laible from Downers Grove, IL, age ~57 Get Report